{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:58:49Z","timestamp":1787500729217,"version":"build-2736575974"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,3,11]],"date-time":"2024-03-11T00:00:00Z","timestamp":1710115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Sacral neuromodulation (SNM) is approved for the treatment of faecal incontinence (FI) in a two\u2010stage technique. With standardized implantation, approximately 90% of patients undergo successful Stage I operation and proceed to a permanent implant (Stage II). The aim of this work was to explore the feasibility of SNM as a one\u2010stage procedure and report the 24\u2010week efficacy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>This study included patients diagnosed with idiopathic FI or FI due to an external anal sphincter defect \u2264160\u00b0 and one or more episodes of FI per week despite maximal conservative therapy. Patients were offered a one\u2010stage procedure if a motor response of the external anal sphincter was achieved in three or more poles with at least one at \u22641.5\u2009mA at lead placement. Patients were followed for 24\u2009weeks. Their evaluation included the Wexner\/St Mark's Incontinence Score, Faecal Incontinence Quality of Life score (FIQoL), a visual analogue scale (VAS) for assessing patient satisfaction and a bowel habit diary.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Seventy\u2010three patients with a median age of 60\u2009years (interquartile range 50\u201369\u2009years) completed this prospective study. Episodes of FI were significantly reduced at the 24\u2010week follow\u2010up, from 13 (8\u201323) at baseline to 2 (0\u20135) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2010value\u2009=\u20090002). A \u226550% reduction in the number of FI episodes was achieved in 92% of participants. The Wexner score improved significantly from 16 (14\u201317) at baseline to 9 (5\u201313) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2010value\u2009&lt;\u20090.001), and the St Mark's score improved significantly from 18 (16\u201320) to 11 (7\u201316) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2010value\u2009&lt;\u20090.001). All domains in the FIQoL score and VAS for patient satisfaction improved significantly following the one\u2010stage procedure.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A one\u2010stage implantation procedure is feasible in selected patients with FI, significantly improving continence, quality of life and patient satisfaction after 24\u2009weeks of follow\u2010up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/codi.16936","type":"journal-article","created":{"date-parts":[[2024,3,11]],"date-time":"2024-03-11T23:19:55Z","timestamp":1710199195000},"page":"968-973","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["One\u2010stage implant in sacral neuromodulation for faecal incontinence \u2013 short\u2010term outcome from a prospective study"],"prefix":"10.1111","volume":"26","author":[{"given":"Jakob","family":"Duelund\u2010Jakobsen","sequence":"first","affiliation":[{"name":"Pelvic Floor Unit, Department of Surgery Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steen","family":"Buntzen","sequence":"additional","affiliation":[{"name":"Pelvic Floor Unit, Department of Surgery Aarhus University Hospital  Aarhus Denmark"},{"name":"Department of Gastroenterological Surgery, National Advisory Board of Incontinence and Pelvic Floor Health of Norway University Hospital of North Norway  Tromsoe Norway"},{"name":"Department of Clinical Medicine Arctic University of North Norway  Tromsoe Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6612-3319","authenticated-orcid":false,"given":"Lilli","family":"Lundby","sequence":"additional","affiliation":[{"name":"Pelvic Floor Unit, Department of Surgery Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f8ren","family":"Laurberg","sequence":"additional","affiliation":[{"name":"Pelvic Floor Unit, Department of Surgery Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"S\u00f8rensen","sequence":"additional","affiliation":[{"name":"Department of Surgical and Medical Gastroenterology Hvidovre University Hospital  Hvidovre Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona","family":"Rydningen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery, National Advisory Board of Incontinence and Pelvic Floor Health of Norway University Hospital of North Norway  Tromsoe Norway"},{"name":"Department of Clinical Medicine Arctic University of North Norway  Tromsoe 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