{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T00:53:57Z","timestamp":1792198437819,"version":"4.4.0"},"reference-count":37,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Follow\u2010up for colorectal cancer (CRC) necessitates regular monitoring of carcinoembryonic antigen (CEA) at the hospital. Capillary home\u2010based blood collection, including minimally invasive techniques such as lancet sampling or an automated upper arm device (TAP\u2010II), has the potential to replace a significant portion of hospital\u2010based blood sampling, thereby enhancing self\u2010reliance and quality of life. The objectives of this study were to assess the feasibility, reliability and preference for CEA blood collection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Baseline venous and capillary (by lancet and TAP\u2010II) blood samples were collected from 102 participants, including 20 CRC patients with elevated CEA levels, 60 CRC patients undergoing postoperative outpatient monitoring and 20 healthy volunteers. The second group performed capillary blood collections at home on two consecutive follow\u2010up appointments and subsequently sent them to the hospital. Satisfaction was assessed via patient reported outcome measures on pain, burden, ease of use and preference.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The Pearson's correlation test of all usable samples resulted in a linear coefficient of 0.998 (95% CI 0.997\u20130.998) for the TAP\u2010II method and 0.997 (95% CI 0.996\u20130.998) for the lancet method, both compared to venipuncture. Following the initial blood collection, 86% of the participants (<jats:italic>n<\/jats:italic>\u2009=\u2009102) favoured the TAP\u2010II, rating it as the least painful and burdensome option. After two home\u2010based blood samples, the preference for the TAP\u2010II method persisted, with 64% of the patients endorsing its use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study demonstrated the feasibility of home\u2010based capillary sampling of CEA. The TAP\u2010II blood collection is the most reliable method and is preferred by patients over venipuncture and lancet sampling.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.17085","type":"journal-article","created":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T10:50:02Z","timestamp":1719831002000},"page":"1560-1568","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Feasibility, reliability and satisfaction of (automated) capillary carcinoembryonic antigen measurements for future home\u2010based blood sampling: the prospective <scp>CASA<\/scp>\u2010I study"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4592-9409","authenticated-orcid":false,"given":"Kelly R.","family":"Voigt","sequence":"first","affiliation":[{"name":"Department of Surgical Oncology and Gastrointestinal Surgery Erasmus MC Cancer Institute  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lissa","family":"Wullaert","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology and Gastrointestinal Surgery Erasmus MC Cancer Institute  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. D.","family":"Gobardhan","sequence":"additional","affiliation":[{"name":"Department of Surgery Amphia Hospital  Breda The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. G.","family":"Doornebosch","sequence":"additional","affiliation":[{"name":"Department of Surgery IJsselland Ziekenhuis  Capelle aan den IJssel The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelis","family":"Verhoef","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology and Gastrointestinal Surgery Erasmus MC Cancer Institute  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Husson","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology and Gastrointestinal Surgery Erasmus MC Cancer Institute  Rotterdam The Netherlands"},{"name":"Department of Medical Oncology Netherlands Cancer Institute  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Ramakers","sequence":"additional","affiliation":[{"name":"Department of Clinical Chemistry Erasmus University Medical Centre  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk J.","family":"Gr\u00fcnhagen","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology and Gastrointestinal Surgery Erasmus MC Cancer Institute  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2021.12.007"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21763"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21708"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2021.07.039"},{"key":"e_1_2_14_7_1","unstructured":"TimesNL.Cancer patients' survival rate increased significantly in past decade: NL Times.2022. Available from: https:\/\/nltimes.nl\/2022\/08\/23\/cancer\u2010patients\u2010survival\u2010rate\u2010increased\u2010significantly\u2010past\u2010decade#:~:text=The%20IKNL%20compared%20the%20survival from%2051%20to%2059%20percent"},{"key":"e_1_2_14_8_1","volume-title":"Aantal diagnoses kanker stijgt komend decennium tot 156.000 per","author":"IKNL, the Netherlands","year":"2022"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgh-2022-009316"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/intqhc\/mzac069"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/nop2.1434"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.janxdis.2006.01.004"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jan.13818"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/tbm\/iby064"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijresmar.2015.05.009"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.20093"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269216318783919"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apnr.2015.05.004"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/17434440.2023.2170783"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11306-018-1395-z"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2022-002641"},{"key":"e_1_2_14_22_1","unstructured":"World Health Organization.Colorectal Cancer: World Health Organization.2023Available from:https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/colorectal\u2010cancer"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2021.12.004"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2020.06.022"},{"key":"e_1_2_14_25_1","unstructured":"(NVvH) NVvH.Follow\u2010up bij CRC\u2014Richtlijn\u2014Richtlijnendatabase.2020Available from:https:\/\/richtlijnendatabase.nl\/richtlijn\/colorectaal_carcinoom_crc"},{"key":"e_1_2_14_26_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000002864"},{"key":"e_1_2_14_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.16536"},{"key":"e_1_2_14_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)90837-8"},{"issue":"11","key":"e_1_2_14_29_1","first-page":"709","article-title":"A new biometrical procedure for testing the equality of measurements from two different analytical methods. Application of linear regression procedures for method comparison studies in clinical chemistry, part I","volume":"21","author":"Passing H","year":"1983","journal-title":"J Clin Chem Clin Biochem"},{"key":"e_1_2_14_30_1","volume-title":"How can I decide the sample size for a study of agreement between two methods of measurement?","author":"Bland JM","year":"2014"},{"key":"e_1_2_14_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/geront\/gny113"},{"key":"e_1_2_14_32_1","doi-asserted-by":"publisher","DOI":"10.2196\/44564"},{"issue":"3","key":"e_1_2_14_33_1","doi-asserted-by":"crossref","DOI":"10.1136\/bmjoq-2020-001192","article-title":"Utilisation of remote capillary blood testing in an outpatient clinic setting to improve shared decision making and patient and clinician experience: a validation and pilot study","volume":"10","author":"Lisa N","year":"2021","journal-title":"BMJ Open Qual"},{"key":"e_1_2_14_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/geroni\/igac057"},{"key":"e_1_2_14_35_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-022-08782-w"},{"key":"e_1_2_14_36_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1995.03520470045030"},{"key":"e_1_2_14_37_1","doi-asserted-by":"publisher","DOI":"10.1093\/bmb\/ldy011"},{"key":"e_1_2_14_38_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-19-1534"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.17085","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T08:42:48Z","timestamp":1724143368000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/codi.17085"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":37,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1111\/codi.17085"],"URL":"https:\/\/doi.org\/10.1111\/codi.17085","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"2024-01-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}