{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T01:31:47Z","timestamp":1791595907133,"version":"4.3.4"},"reference-count":41,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,3]],"date-time":"2025-02-03T00:00:00Z","timestamp":1738540800000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100008363","name":"Kr\u00e6ftens Bek\u00e6mpelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008363","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Sexual dysfunction after colorectal and anal cancer is common but rarely identified and treated, although effective treatment options do exist. Therefore, we recently established nurse\u2010led clinics for the treatment of sexual dysfunction after pelvic organ cancer at two Danish university hospitals. The aim of this paper is to present patients' clinical characteristics, the treatments offered and improvements in sexual function recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>In this cohort study, colorectal and anal cancer patients were referred to the clinics at any time point after their cancer treatment. Specialized treating nurses identified and registered organic sexual disorders and psychological concerns at the first visit, and initiated treatments. Treatments were algorithm\u2010based and rooted in a biopsychosocial approach. Patient\u2010reported outcome measures were completed at baseline and 3\u2009months after discharge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 127 referred patients, 78% were men. The mean age was 60.6\u2009years (SD 10.4\u2009years) and the women were a mean 7.3\u2009years younger than the men (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). Eighty per cent were rectal cancer patients. The most prevalent disorder was erectile dysfunction in men (95%) and dyspareunia in women (71%). Psychological concerns were registered in 53% of men and 54% of women. Pharmacological treatments, mainly phosphodiesterase\u20105 inhibitors, were prescribed to 87% of men, and local oestrogens were prescribed to 54% of women. Instructions in the use of sexual aids were given to 22% of men and 42% of women. Furthermore, sexual counselling\/therapy was offered to 44% of men and 92% of women to address sexuality related psychological problems. Three months after discharge, a clinically relevant improvement of \u22651 point was found in 68% of patients in at least one of three single items measuring \u2018Meaningful sex life\u2019, \u2018Sexual needs met\u2019 and \u2018Overall rating of sex life\u2019 on a five\u2010point Likert\u2010scale.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>At nurse\u2010led clinics, specialized nurses can effectively identify and treat sexual problems in patients with sexual dysfunction following colorectal\/anal cancer. Organic dysfunctions were prevalent, and psychological problems characterized most patients. This highlights that treatment needs to be multidisciplinary and that patients benefit from specialized care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/codi.70018","type":"journal-article","created":{"date-parts":[[2025,2,3]],"date-time":"2025-02-03T22:54:56Z","timestamp":1738623296000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Sexual dysfunction after colorectal and anal cancer\u2014treatment in nurse\u2010led sexological clinics"],"prefix":"10.1111","volume":"27","author":[{"given":"Anette H\u00f8jer","family":"Mikkelsen","sequence":"first","affiliation":[{"name":"Sexological Center Aalborg University Hospital  Aalborg Denmark"},{"name":"Danish Cancer Society, National Research Center for Survivorship and Late Adverse Effects Following Pelvic Organ Cancer Aarhus and Aalborg University Hospitals  Aarhus &amp; Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Thy\u00f8","sequence":"additional","affiliation":[{"name":"Danish Cancer Society, National Research Center for Survivorship and Late Adverse Effects Following Pelvic Organ Cancer Aarhus and Aalborg University Hospitals  Aarhus &amp; 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Aalborg Denmark"},{"name":"Sexology Research Center, Department of Clinical Medicine Aalborg University  Gistrup Denmark"},{"name":"Clinical Nursing Research Center Aalborg University Hospital  Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Christensen","sequence":"additional","affiliation":[{"name":"Danish Cancer Society, National Research Center for Survivorship and Late Adverse Effects Following Pelvic Organ Cancer Aarhus and Aalborg University Hospitals  Aarhus &amp; Aalborg Denmark"},{"name":"Department of Surgery Aarhus University Hospital  Aarhus Denmark"},{"name":"Department of Clinical Medicine Aarhus University  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina","family":"Schwennesen","sequence":"additional","affiliation":[{"name":"Danish Cancer Society, National Research Center for Survivorship and Late Adverse Effects Following Pelvic Organ Cancer Aarhus and Aalborg University Hospitals  Aarhus &amp; 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