{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T20:39:47Z","timestamp":1793651987568,"version":"4.5.1"},"reference-count":44,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T00:00:00Z","timestamp":1739232000000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The aim of this work was to evaluate whether the therapeutic quality of exercise prehabilitation programmes is associated with their effectiveness to preoperatively improve aerobic fitness and reduce postoperative complications and length of hospital stay in patients scheduled for colorectal surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Three electronic databases (PubMed, Embase and CINAHL) were systematically searched (up to October 2023) for randomized controlled trials that investigated the effects of prehabilitation before colorectal resection. Methodological quality and therapeutic quality were assessed using, respectively, the Cochrane Risk of Bias 2 tool and the i\u2010CONTENT tool. Studies were divided into four subgroups based on the estimated risk of bias and risk of ineffectiveness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Fourteen studies were included, comprising 986 patients. Meta\u2010analysis showed that, in general, prehabilitation improved preoperative aerobic fitness but did not improve postoperative outcomes. No differences were found between the four subgroups; however, only one study (7%) had a low risk of bias in combination with a low risk of ineffectiveness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The fact that only one study had a low risk of bias in combination with a low risk of ineffectiveness precluded us from establishing an association between therapeutic quality and the effectiveness of prehabilitation on postoperative outcomes. The quality of future prehabilitation research with exercise interventions should be improved by using an assessment tool during the design phase of prehabilitation programmes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/codi.70023","type":"journal-article","created":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T23:34:51Z","timestamp":1739316891000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Evaluating the therapeutic quality of prehabilitation programmes in patients scheduled for colorectal surgery: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0489-0716","authenticated-orcid":false,"given":"Evy E. J.","family":"Jetten","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery VieCuri Medical Centre  Venlo The Netherlands"},{"name":"Department of Clinical Epidemiology VieCuri Medical Centre  Venlo The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruud F. W.","family":"Franssen","sequence":"additional","affiliation":[{"name":"Department of Clinical Physical Therapy VieCuri Medical Centre  Venlo The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa J. J.","family":"Voorn","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Care and Public Health Research Institute Maastricht University  Maastricht The Netherlands"},{"name":"Adelante Rehabilitation Centre  Venlo The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Falz","sequence":"additional","affiliation":[{"name":"Institute of Sport Medicine and Prevention University Leipzig  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Busse","sequence":"additional","affiliation":[{"name":"Institute of Sport Medicine and Prevention University Leipzig  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1948-9788","authenticated-orcid":false,"given":"Bart C.","family":"Bongers","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Movement Sciences, Institute of Nutrition and Translational Research in Metabolism (NUTRIM) Maastricht University  Maastricht The Netherlands"},{"name":"Department of Surgery, Institute of Nutrition and Translational Research in Metabolism (NUTRIM) Maastricht University  Maastricht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryska L. 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