{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T13:13:21Z","timestamp":1792761201510,"version":"4.5.0"},"reference-count":42,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:00:00Z","timestamp":1741824000000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Complete mesocolic excision (CME) for colon cancer has been associated with improved oncological outcomes but requires a detailed understanding of complex mesenteric vasculature. Three\u2010dimensional (3D) reconstructed models derived from patient imaging could enhance preoperative anatomical comprehension, enabling safer, precision CME.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this two\u2010phase, blinded, crossover study, four expert CME surgeons evaluated mesenteric vascular anatomy on CT scans and 3D models. In phase 1, surgeons assessed 66 cases, while 20 were re\u2010evaluated in phase 2. The primary outcome measure was inter\u2010rater reliability by Fleiss's kappa. Secondary outcomes were intra\u2010rater reliability by Cohen's kappa and anatomical accuracy rates measured as a percentage of correct responses on a standardised questionnaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In phase 1, inter\u2010rater agreement was higher for 3D models (average kappa 0.6, moderate agreement) than for CT scans (average kappa 0.1, poor agreement). Ileocolic vein drainage and ileocolic artery trajectory showed the highest kappa values with 3D imaging (0.85 and 0.93, respectively). Accuracy was also superior with 3D across all surgeons (mean 89.7% correct) versus CT (mean 79.1% correct, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). In phase 2, intra\u2010rater reliability remained higher for 3D (average Cohen's kappa 0.61) than CT scans (Cohen's kappa 0.27).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>3D mesenteric models significantly improve inter\u2010 and intra\u2010rater reliability among CME experts over traditional CT scans while markedly enhancing anatomical comprehension accuracy about critical right\u2010sided colonic vasculature. 3D planning could facilitate CME by enabling superior preoperative visualisation of these vessels.<\/jats:p><\/jats:sec>","DOI":"10.1111\/codi.70025","type":"journal-article","created":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T06:06:40Z","timestamp":1741932400000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Inter\u2010rater and intra\u2010rater reliability of multi\u2010slice <scp>CT<\/scp> and <scp>three\u2010dimensional<\/scp> reconstructed imaging analysis of mesenteric vascular anatomy for planning and performing complete mesocolic excision"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4615-4315","authenticated-orcid":false,"given":"Jordan","family":"Fletcher","sequence":"first","affiliation":[{"name":"St Mark's Hospital and Academic Institute  Harrow Middlesex UK"},{"name":"Department of Surgery and Cancer Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillip","family":"Lung","sequence":"additional","affiliation":[{"name":"St Mark's Hospital and Academic Institute  Harrow Middlesex UK"},{"name":"Department of Surgery and Cancer Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen","family":"Van Eetvelde","sequence":"additional","affiliation":[{"name":"Department of Surgery University Hospital UZ Brussel  Jette Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6337-8447","authenticated-orcid":false,"given":"Claus Anders","family":"Bertelsen","sequence":"additional","affiliation":[{"name":"Department of Surgery Copenhagen University Hospital \u2013 North Zealand  Hiller\u00f8d Denmark"},{"name":"Department of Clinical Medicine, Faculty of Health and Medical Sciences University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4327-7360","authenticated-orcid":false,"given":"Adam","family":"Stearns","sequence":"additional","affiliation":[{"name":"Department of Surgery Norfolk and Norwich University Hospitals NHS Foundation Trust  Norwich UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristian","family":"Storli","sequence":"additional","affiliation":[{"name":"Department of Surgery, Haraldsplass Deaconess Hospital University of Bergen  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danilo","family":"Miskovic","sequence":"additional","affiliation":[{"name":"St Mark's Hospital and Academic Institute  Harrow Middlesex UK"},{"name":"Department of Surgery and Cancer Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,13]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463\u20101318.2008.01735.x"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384\u2010013\u20101818\u20102"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.13900"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/1538574417739749"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.11387"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470\u20102045(20)30685\u20109"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.15644"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010021\u201010186\u20109"},{"key":"e_1_2_13_10_1","unstructured":"Laparoscopic CME programme. 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