{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T23:38:27Z","timestamp":1789256307220,"version":"build-2803163510"},"reference-count":44,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T00:00:00Z","timestamp":1754352000000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100015738","name":"Mary och Georg C. Ehrnrooths Stiftelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015738","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003125","name":"Suomen Kulttuurirahasto","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003125","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010711","name":"Sy\u00f6p\u00e4s\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010711","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>An increasing number of elective colon cancer surgeries are performed on older patients. Frail patients are at a higher risk of postoperative adverse events and early mortality. This prospective, multicentre, observational study aimed to analyse preoperative screening tools and the long\u2010term survival of older patients having elective colon cancer surgery. The focus was on patients who survived more than 3\u2009months postoperatively, excluding the effect of early postoperative mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients aged \u226580\u2009years with electively operated stage I\u2010III colon cancer were recruited. Prospectively collected data included comorbidities, functional and frailty status, postoperative outcomesand long\u2010term survival. Univariate and multivariable Cox regression analyses were conducted to determine factors associated with long\u2010term survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 227 surgical patients were included. Survival rates at 1 and 3\u2009years were 94% and 74% for all patients and 86% and 57% for patients with Clinical Frailty Scale (CFS) 5\u20139, respectively. In multivariable regression analysis, CFS 5\u20139 (HR 3.16, 95% CI 1.31\u20137.63,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.011) and tumour stage III (HR 2.50, 1.16\u20135.39,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.020) were the patient\u2010related variables affecting survival among those surviving over 3\u2009months postoperatively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Preoperative frailty assessed by CFS predicts long\u2010term survival in older patients after curative colon cancer surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/codi.70190","type":"journal-article","created":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T04:48:32Z","timestamp":1754455712000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Clinical Frailty Scale predicts overall survival after colon cancer surgery in people aged 80\u2009years and older: A prospective multicentre observational study"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1910-2640","authenticated-orcid":false,"given":"Susanna","family":"Niemel\u00e4inen","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Alimentary Tract Surgery Tampere University Hospital  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marja","family":"Hy\u00f6ty","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Alimentary Tract Surgery Tampere University Hospital  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anu","family":"Ehrlich","sequence":"additional","affiliation":[{"name":"Department of Abdominal Surgery Helsinki University Hospital  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esa","family":"J\u00e4msen","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Helsinki University  Helsinki Finland"},{"name":"Department of Geriatrics Helsinki University Hospital  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selja","family":"Koskensalo","sequence":"additional","affiliation":[{"name":"Department of Abdominal Surgery Helsinki University Hospital  Helsinki Finland"},{"name":"Faculty of Medicine Helsinki University  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyrki","family":"K\u00f6ssi","sequence":"additional","affiliation":[{"name":"Department of Surgery P\u00e4ij\u00e4t\u2010H\u00e4me Central Hospital  Lahti Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarja","family":"Pinta","sequence":"additional","affiliation":[{"name":"Sein\u00e4joki Central Hospital  Sein\u00e4joki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna","family":"Vihervaara","sequence":"additional","affiliation":[{"name":"Division of Digestive Surgery and Urology Turku University Hospital  Turku Finland"},{"name":"Faculty of Medicine Turku University  Turku Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heini","family":"Huhtala","sequence":"additional","affiliation":[{"name":"Faculty of Social Sciences Tampere University  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,5]]},"reference":[{"key":"e_1_2_12_2_1","unstructured":"Statistics Finland. 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