{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T11:15:42Z","timestamp":1789038942057,"version":"build-2803163510"},"reference-count":37,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T00:00:00Z","timestamp":1754524800000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100015459","name":"Danish Cancer Society Research Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015459","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Chronic pain affects approximately 30% of rectal cancer (RC) survivors, significantly impairing their quality of life (QoL). The Rectal Cancer Pain Score (RCPS) was developed to evaluate chronic pain in RC patients. While its psychometric properties have been demonstrated in cross\u2010sectional studies on long\u2010term survivors, validation in a longitudinal cohort is necessary to establish its utility throughout recovery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Patients undergoing RC surgery at three Danish hospitals were enrolled in a prospective cohort\u2010screening program for late sequelae. Patients completed the RCPS, the EQ\u20105D\u20105L questionnaire and a question regarding the impact of pain on QoL (scored from 1, \u2018Not at all\u2019 to 5 \u2018Very much\u2019) at 3\u2010, 12\u2010, 24\u2010 and 36 months post\u2010surgery. The RCPS's validity was assessed through the predictive ability of requests for pain\u2010related contact, correlations with self\u2010rated pain impact and associations with QoL. Known\u2010groups validity was evaluated by comparing pain impact and pain referrals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 729 patients (mean age 67\u2009years, 36% female) were included. Higher pain scores at 12\u2009months significantly predicted requests for future contacts regarding pain (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), supporting predictive validity. The RCPS demonstrated strong concurrent validity, correlating highly with self\u2010rated pain impact (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and there were significant differences in the request for contact between pain impact groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), confirming construct and known\u2010group validity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The RCPS is a valid tool for screening rectal cancer patients prospectively for chronic pain during the follow\u2010up period. Its integration into routine follow\u2010up programs may enable earlier identification and tailored management of chronic pain.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/codi.70198","type":"journal-article","created":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T03:59:43Z","timestamp":1754625583000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Rectal Cancer Pain Score: A prospective cohort validation study across recovery stages"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4720-0718","authenticated-orcid":false,"given":"Louise","family":"Kuhlmann","sequence":"first","affiliation":[{"name":"Mech\u2010Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital  Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrine J.","family":"Emmertsen","sequence":"additional","affiliation":[{"name":"Department of Surgery Regional Hospital Randers  Randers Denmark"},{"name":"Danish Cancer Society Centre for Research on Survivorship and Late Adverse Effects after Cancer in the Pelvic Organs  Aalborg Denmark"},{"name":"Department of Clinical Medicine Aarhus University  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6528-5639","authenticated-orcid":false,"given":"Marianne","family":"Krogsgaard","sequence":"additional","affiliation":[{"name":"Department of Surgery Center for Surgical Science, Zealand University Hospital K\u00f8ge  K\u00f8ge Denmark"},{"name":"Department of People and Technology Roskilde University  Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina A.","family":"Frederiksen","sequence":"additional","affiliation":[{"name":"Department of Surgery Center for Surgical Science, Zealand University Hospital K\u00f8ge  K\u00f8ge Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B.","family":"Lauritzen","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery Aalborg University Hospital  Aalborg Denmark"},{"name":"Department of Clinical Medicine Aalborg University  Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Christensen","sequence":"additional","affiliation":[{"name":"Danish Cancer Society Centre for Research on Survivorship and Late Adverse Effects after Cancer in the Pelvic Organs  Aalborg Denmark"},{"name":"Department of Clinical Medicine Aarhus University  Aarhus Denmark"},{"name":"Department of Surgery Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5411-4826","authenticated-orcid":false,"given":"Therese","family":"Juul","sequence":"additional","affiliation":[{"name":"Danish Cancer Society Centre for Research on Survivorship and Late Adverse Effects after Cancer in the Pelvic Organs  Aalborg Denmark"},{"name":"Department of Clinical Medicine Aarhus University  Aarhus Denmark"},{"name":"Department of Surgery Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asbj\u00f8rn M.","family":"Drewes","sequence":"additional","affiliation":[{"name":"Mech\u2010Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital  Aalborg Denmark"},{"name":"Department of Clinical Medicine Aalborg University  Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,7]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2016.05.027"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/pme.12223"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000000237"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300060517693421"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.5918"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19841201)54:2 <2635::AID-CNCR2820541407>3.0.CO;2-P"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1586\/14737167.6.5.591"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aen103"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.14436"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.16339"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.15519"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2019.103208"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-47622-9_1"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.15352"},{"key":"e_1_2_12_16_1","unstructured":"MD Anderson Cancer Center.The Brief Pain Inventory. 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