{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T19:27:08Z","timestamp":1783366028656,"version":"3.54.6"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T00:00:00Z","timestamp":1760227200000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The oncological benefit of D3 lymph node dissection (D3 LND) for colon cancer in patients aged \u226590\u2009years remains unclear. This study aimed to evaluate the impact of D3 LND on outcomes in this specific, vulnerable population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>This retrospective cohort study evaluated 166 patients aged \u226590\u2009years with pathological Stages II\u2013III colon cancer undergoing non\u2010D3 or D3 LND from a multicentre database (2011\u20132022). Postoperative complications, overall survival and cancer\u2010specific survival were compared between LND groups using propensity score\u2010weighted analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      D3 LND group had significantly more females and laparoscopic procedures. Operation time was longer, and blood loss was lower in the D3 LND group. Postoperative complications and severe complications were significantly fewer, and postoperative hospital stay was shorter in the D3 LND group. The number of harvested lymph nodes and distal margin was significantly higher in the D3 group. While unadjusted analysis showed better overall survival with D3 LND (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), adjusted cancer\u2010specific survival showed no significant difference (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.10). Adjusted mortality risk was significantly higher in the non\u2010D3 group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In nonagenarian colon cancer patients, D3 LND is safe and feasible without increasing complications, but lacks survival benefit. Careful consideration is warranted, and high\u2010quality D2 LND must be consistently ensured when limited surgery is chosen.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/codi.70269","type":"journal-article","created":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T04:35:18Z","timestamp":1760330118000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["D3 lymph node dissection in colon cancer patients aged 90\u2009years and over: Is it justified? A multi\u2010institutional retrospective study"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5133-2644","authenticated-orcid":false,"given":"Fuminori","family":"Teraishi","sequence":"first","affiliation":[{"name":"Department of Surgery National Hospital Organization Fukuyama Medical Center  Hiroshima Japan"},{"name":"Department of Gastroenterological Surgery Okayama University Hospital  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoe","family":"Takanaga","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Okayama University Hospital  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Inada","sequence":"additional","affiliation":[{"name":"Department of Surgery Kochi Health Sciences Center  Kochi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiharu","family":"Mitsuhashi","sequence":"additional","affiliation":[{"name":"Center for Innovative Clinical Medicine, Medical Development Field Okayama University  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiaki","family":"Toshima","sequence":"additional","affiliation":[{"name":"Department of Surgery Kagawa Rosai Hospital  Kagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsuyoshi","family":"Ohtani","sequence":"additional","affiliation":[{"name":"Department of Surgery Saiseikai Okayama Hospital  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryosuke","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Surgery Okayama Rosai Hospital  Okayama 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