{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T10:28:52Z","timestamp":1788517732664,"version":"build-2803163510"},"reference-count":16,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T00:00:00Z","timestamp":1763337600000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Ablation of anal fistula tract using a radial laser\u2010emitting probe is a sphincter\u2010preserving technique.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The objective of investigating the safety and efficacy of laser treatment for complex anal fistula.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>This was a prospective and observational analysis of the long\u2010term outcomes of 172 patients who underwent laser ablation of the fistula tract.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Settings<\/jats:title>\n                    <jats:p>This was a multicentre, single\u2010arm study, involving 20 Spanish centres.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients<\/jats:title>\n                    <jats:p>Patients with cryptoglandular anal fistulas with an external orifice, high intersphincteric fistula or low intersphincteric fistula with faecal incontinence, transsphincteric fistula and suprasphincteric fistula.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>A probe housing a 12\u2010watt laser emitting at a wavelength of 1470\u2009nm and an energy level of 100 joule\/cm was used.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures<\/jats:title>\n                    <jats:p>Complete treatment success was defined as the closure of the external opening and the absence of fistula drainage, with closure of the fistula tract confirmed by clinical evaluation. Partial success was defined as the external opening remaining open but without drainage. Surgical complications, including continence disorders, were also assessed. Patients were evaluated at 1, 3, 6, and 12\u2009months after surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 172 patients underwent laser ablation of the fistula tract with a median age of 51 (43\u201361) years. The majority of them were men (62,8%). A total of 133 patients (77.32%) were followed up for a minimum of 12\u2009months. The number of patients with complete healing was 59 (44.3%) and partial healing was observed in seven (5.26%). Healing (clinical and radiological) was not achieved in 67 patients (50.37%). Nine reported adverse events. None of the patients experienced permanent anal incontinence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Limitations<\/jats:title>\n                    <jats:p>It is the loss to follow\u2010up of up to 20% of patients, as many patients do not tolerate waiting within a strict visit schedule.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Laser ablation of the fistula tract is a sphincter\u2010preserving procedure with an acceptable long\u2010term success rate.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/codi.70302","type":"journal-article","created":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T04:04:36Z","timestamp":1763438676000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["National observational study about the surgical treatment of anal fistula with laser (the\n                    <scp>FISTULASER<\/scp>\n                    study)"],"prefix":"10.1111","volume":"27","author":[{"given":"Fernando","family":"de la Portilla de Juan","sequence":"first","affiliation":[{"name":"Chief of Colorectal Unit, Department of General and Digestive Surgery University Hospital Virgen del Roc\u00edo, Seville University  Seville Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda L.","family":"Reyes D\u00edaz","sequence":"additional","affiliation":[{"name":"Department of General and Digestive Surgery University Hospital Virgen del Roc\u00edo  Seville Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3049-4999","authenticated-orcid":false,"given":"Ana Huidobro","family":"Piriz","sequence":"additional","affiliation":[{"name":"Department of General and Digestive Surgery Complejo Asistencial Universitario de Palencia  Palencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soledad Oliart","family":"Delgado","sequence":"additional","affiliation":[{"name":"Department of General and Digestive Hospital Central de la Cruz Roja  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa Pelaez","family":"Barrig\u00f3n","sequence":"additional","affiliation":[{"name":"Department of General and Digestive Hospital Hospital Virgen de la Concha  Zamora Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lourdes Gomez","family":"Bujedo","sequence":"additional","affiliation":[{"name":"Department of General and Digestive Surgery University Hospital Valme, Seville University  Seville Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa Calderon","family":"Duque","sequence":"additional","affiliation":[{"name":"Department of General and Digestive Hospital Nuestra Se\u00f1ora del Prado  Talavera de la Reina Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bego\u00f1a","family":"Ochoa","sequence":"additional","affiliation":[{"name":"Colorectal Unit, Department of General and Digestive Surgery Hospital de Basurto\u2010Osakidetza  Bilbao Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"FISTULASER Study Group Collaborators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,17]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-005-0055-3"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-023-01912-z"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.13330"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-020-02165-1"},{"key":"e_1_2_12_6_1","first-page":"213","article-title":"Analysis and description of disease\u2010specific quality of life in patients with anal fistula","volume":"96","author":"Ferrer\u2010M\u00e1rquez M","year":"2018","journal-title":"Cir Esp (Engl Ed)"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000067"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-021-03932-8"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-015-1282-9"},{"key":"e_1_2_12_10_1","first-page":"163","article-title":"Laser surgery of anal fistulae","volume":"29","author":"Quaresimini G","year":"2016","journal-title":"Chirurgia\u2010Italy"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-017-1599-7"},{"key":"e_1_2_12_12_1","first-page":"142","article-title":"Closure of fistula tract with FilacTM laser as a sphincter preserving method in anal fistula treatment","volume":"27","author":"D\u00f6nmez T","year":"2017","journal-title":"Turkish J Color 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