{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T17:27:47Z","timestamp":1780421267018,"version":"3.54.1"},"reference-count":40,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:00:00Z","timestamp":1763078400000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Acute abscess\u2010forming pilonidal sinus disease (PSD) is treated surgically, with lateral incision and drainage (I&amp;D) considered the gold standard; however, the risk of re\u2010operation is unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To evaluate re\u2010operation rates following abscess\u2010forming PSD treatment with lateral I&amp;D, and to identify factors influencing re\u2010operation rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using data from nationwide Danish databases covering 2010\u20132021, we identified patients diagnosed with abscess\u2010forming PSD undergoing lateral I&amp;D as the initial treatment for PSD. Patients were followed up until re\u2010operation, death, emigration, or the end of the study period. Stratified by sex, the risk of re\u2010operation was reported as a cumulative incidence function (CIF). To explore risks, we used Cox regression analysis to calculate crude and age\u2010adjusted hazard ratios (aHR).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 8251 (62% male) patients included, 2455 underwent re\u2010operation for PSD. The overall five\u2010year CIF was 32% for males and 33% for females. In males, the five\u2010year CIF decreased from 47% among 0\u2010 to 16\u2010year\u2010olds to 14% among 50+ year\u2010olds. In females, the corresponding numbers were 37% and 13%, respectively. A family history of PSD was found to increase re\u2010operation risk, especially among female patients (aHR: 1.64 (95% confidence interval [95% CI]: 1.39\u20131.93)). The risk increases following the second and third consecutive I&amp;D procedures to 52% and 69% in males, and to 57% and 64% in females, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>As roughly two\u2010thirds of patients do not require additional surgery, our findings do not support mandatory follow\u2010up with definitive surgery for all PSD patients undergoing I&amp;D. For certain high\u2010risk subgroups, however, subsequent definitive surgery may be appropriate.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/codi.70307","type":"journal-article","created":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T06:20:23Z","timestamp":1763187623000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Risk of re\u2010operation after incision and drainage for acute, abscess\u2010forming pilonidal sinus disease: A Danish population\u2010based cohort study"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9760-5345","authenticated-orcid":false,"given":"Ida Kaad","family":"Faurschou","sequence":"first","affiliation":[{"name":"Pilonidal Disease Center, Department of Surgery Randers Regional Hospital  Randers Denmark"},{"name":"Department of Clinical Epidemiology Aarhus University Hospital and Aarhus University  Aarhus Denmark"},{"name":"Department of Clinical Medicine Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rune","family":"Erichsen","sequence":"additional","affiliation":[{"name":"Pilonidal Disease Center, Department of Surgery Randers Regional Hospital  Randers Denmark"},{"name":"Department of Clinical Medicine Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dietrich","family":"Doll","sequence":"additional","affiliation":[{"name":"Department of Procto\u2010Surgery &amp; Pilonidal Sinus, St. Marienhospital Vechta Academic Teaching Hospital of the MHH Hannover  Vechta Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2135-433X","authenticated-orcid":false,"given":"Susanne","family":"Haas","sequence":"additional","affiliation":[{"name":"Pilonidal Disease Center, Department of Surgery Randers Regional Hospital  Randers Denmark"},{"name":"Department of Clinical Medicine Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,14]]},"reference":[{"key":"e_1_2_12_2_1","first-page":"567","article-title":"Pilonidal disease: origin from follicles of hairs and results of follicle removal as treatment","volume":"87","author":"Bascom J","year":"1980","journal-title":"Surgery"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.1992.tb07208.x"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.17227"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-020-02060-1"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjs\/znae237"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjs\/znae281"},{"key":"e_1_2_12_8_1","article-title":"Treatment of pilonidal sinuses in Denmark is not optimal","volume":"57","author":"Fabricius R","year":"2010","journal-title":"Dan Med Bull"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02554755"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.17254"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2012.08007.x"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sopen.2022.03.009"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-20143-4"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjpso.2024.100132"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.17169"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181a87607"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.70003"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-007-9031-4"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpag.2022.08.005"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000002336"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.17927"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S179083"},{"key":"e_1_2_12_23_1","unstructured":"Statistics Denmark: population figures.2024. 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