{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T15:05:00Z","timestamp":1779289500801,"version":"3.51.4"},"reference-count":10,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,11,23]],"date-time":"2025-11-23T00:00:00Z","timestamp":1763856000000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2025,11]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Racial\/ethnic disparities were reported to impact the phenotype of inflammatory bowel disease and its treatment. The impact of race\/ethnicity on ileal pouch anal anastomosis (IPAA's) outcomes is unknown. Our aim was to investigate whether it impacts IPAA's outcomes.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A prospectively maintained IPAA database(1983\u20132022) was searched to identify patients with IPAA who had race\/ethnicity data available regardless of diagnosis. The cohort was divided into 2 groups: Whites and Non\u2010Whites. We analysed patients' demographics, postoperative complications, Kaplan\u2013Meier pouch survival, function (stool number, seepage), quality of life (QoL) scores, social, dietary and sexual restrictions.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 4954 patients were included, with 4674 whites and 280 non\u2010whites. Non\u2010Whites consisted of Black (123, 44%), Asians (23, 8.2%) and Hispanics (134, 48%). The groups were comparable in terms of age, gender and pathological diagnosis (\n p<\/jats:italic>\n \u2009=\u20090.16). The rate of long\u2010term anastomotic leaks, pelvic sepsis and strictures was not significantly different between groups. There was a higher rate of pouchitis in White (29%) vs. Non\u2010White (18%) (\n p<\/jats:italic>\n \u2009<\u20090.001); fistula [White (8%) vs. Non\u2010White (4.5%) (\n p<\/jats:italic>\n \u2009=\u20090.04)] and postoperative obstruction [White (13%) vs. Non\u2010White (9%) (\n p<\/jats:italic>\n \u2009=\u20090.04)]. The Kaplan\u2013Meier pouch retention was similar (97% at 5\u2009years, 96% at 10\u2009years and 95% at 15\u2009years) in White and Non\u2010White patients. The average QoL scores were comparable between Non\u2010White (7.7\u2009\u00b1\u20092.5) and White (7.9\u2009\u00b1\u20092.4) (\n p<\/jats:italic>\n \u2009=\u20090.34). Non\u2010Whites had more social restrictions (25%) vs. Whites (15%) (\n p<\/jats:italic>\n \u2009=\u20090.04).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n In a large IPAA cohort, more White patients had pouchitis compared to Non\u2010White patients. Social restrictions were more prevalent in Non\u2010White patients compared to those in White patients over the long term. More research is needed to understand how race\/ethnicity impacts the IPAA outcomes.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/codi.70316","type":"journal-article","created":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T04:41:03Z","timestamp":1763959263000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Does ethnicity impact the long\u2010term outcome after restorative proctocolectomy with ileal pouch anal anastomosis?"],"prefix":"10.1111","volume":"27","author":[{"given":"Olga","family":"Lavryk","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery Cleveland Clinic Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arielle","family":"Kanters","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Cleveland Clinic Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hermann","family":"Kessler","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Cleveland Clinic Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2549-9042","authenticated-orcid":false,"given":"Stefan D.","family":"Holubar","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Cleveland Clinic Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8632-6065","authenticated-orcid":false,"given":"David","family":"Liska","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Cleveland Clinic Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott R.","family":"Steele","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Cleveland Clinic Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tracy L.","family":"Hull","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Cleveland Clinic Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,23]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/crocol\/otab016"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000030216"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102036.2009.04054.x"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3180335bb3"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izac124"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21431"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463\u20101318.2008.01727.x"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2019.06.030"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/crocol\/otad072"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2022.09.024"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.70316","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T04:55:21Z","timestamp":1764046521000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/codi.70316"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1111\/codi.70316"],"URL":"https:\/\/doi.org\/10.1111\/codi.70316","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"2025-01-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70316"}}