{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T09:14:40Z","timestamp":1780996480249,"version":"3.54.1"},"reference-count":23,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T00:00:00Z","timestamp":1765929600000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62275095"],"award-info":[{"award-number":["62275095"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFC2400102"],"award-info":[{"award-number":["2021YFC2400102"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017531","name":"Medical and Health Research Project of Zhejiang Province","doi-asserted-by":"publisher","award":["2025KY1274"],"award-info":[{"award-number":["2025KY1274"]}],"id":[{"id":"10.13039\/501100017531","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Anastomotic leakage (AL) is a devastating complication following anterior rectal resection. This study aimed to evaluate whether a strategy utilizing real\u2010time Laser Speckle Contrast Imaging (LSCI) for intraoperative perfusion assessment could reduce the incidence of AL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a single\u2010centre study comparing a prospective cohort undergoing LSCI\u2010guided surgery (LSCI group) with a historical cohort (retrospective group). Propensity score matching (PSM) was used to balance baseline characteristics. The LSCI system was used to objectively assess bowel perfusion and guide the selection of the proximal transection site. The primary outcome was the rate of anastomotic leakage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After PSM, 105 patients in the LSCI group were matched with 176 patients in the control group, with all baseline characteristics being comparable. The incidence of AL was significantly lower in the LSCI group compared to the control group (1.9% vs. 8.5%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Furthermore, the rate of severe postoperative infective complications requiring major intervention (percutaneous drainage or reoperation) was also significantly reduced in the LSCI group (1.9% vs. 9.6%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02). In the LSCI group, real\u2010time perfusion assessment led to an intraoperative change of the planned anastomotic site in 6 patients (5.7%), predominantly in low\u2010to\u2010middle rectal cancer cases.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The use of an LSCI\u2010guided strategy for real\u2010time intraoperative perfusion assessment may reduce the rates of both AL and severe postoperative infective complications undergoing ARR surgery. This objective, quantitative technology is a valuable tool for optimizing surgical decision\u2010making and improving patient outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/codi.70340","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T04:10:23Z","timestamp":1766031023000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Laser speckle contrast imaging for real\u2010time assessment of colonic perfusion to prevent anastomotic leakage after anterior rectal resection: A single\u2010centre prospective pilot study"],"prefix":"10.1111","volume":"27","author":[{"given":"Jiazi","family":"Yu","sequence":"first","affiliation":[{"name":"The Second Hospital of Zhejiang University  Hangzhou People's Republic of China"},{"name":"Department of Colorectal Surgery Ningbo Medical Center Lihuili Hospital  Ningbo People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Ningbo Medical Center Lihuili Hospital  Ningbo People's Republic of China"},{"name":"The Affiliated Lihuili Hospital of Ningbo University  Ningbo People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiling","family":"Du","sequence":"additional","affiliation":[{"name":"Yinzhou No. 3 Hospital  Ningbo People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Ningbo Medical Center Lihuili Hospital  Ningbo People's Republic of China"},{"name":"The Affiliated Lihuili Hospital of Ningbo University  Ningbo People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mian","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Ningbo Medical Center Lihuili Hospital  Ningbo People's Republic of China"},{"name":"The Affiliated Lihuili Hospital of Ningbo University  Ningbo People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yupeng","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Ningbo Medical Center Lihuili Hospital  Ningbo People's Republic of China"},{"name":"The Affiliated Lihuili Hospital of Ningbo University  Ningbo People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyi","family":"Yi","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Ningbo Medical Center Lihuili Hospital  Ningbo People's Republic of China"},{"name":"The Affiliated Lihuili Hospital of Ningbo University  Ningbo People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinling","family":"Lu","sequence":"additional","affiliation":[{"name":"Britton Chance Center of Biomedical Photonics, Advanced Biomedical Imaging Facility Wuhan National Laboratory for Optoelectronics\u2010Huazhong University of Science and Technology  Wuhan Hubei People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengcheng","family":"Li","sequence":"additional","affiliation":[{"name":"Britton Chance Center of Biomedical Photonics, Advanced Biomedical Imaging Facility Wuhan National Laboratory for Optoelectronics\u2010Huazhong University of Science and Technology  Wuhan Hubei People's Republic of China"},{"name":"State Key Laboratory of Digital Medical Engineering, Key Laboratory of Biomedical Engineering of Hainan Province, School of Biomedical Engineering Hainan University  Sanya People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzhan","family":"Zhang","sequence":"additional","affiliation":[{"name":"The Second Hospital of Zhejiang University  Hangzhou People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,17]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-024-10705-1"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0041-1735265"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000003478"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000002334"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-018-3954-z"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.14469"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3182a6f2fc"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjs\/znad154"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000023135"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000005907"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-021-08973-2"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-019-06730-0"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.15037"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2025.0006"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-023-10140-8"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjsopen\/zraa074"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000003098"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-022-09536-9"},{"key":"e_1_2_12_20_1","article-title":"Revised Strengthening the reporting of cohort, cross\u2010sectional and case\u2010control studies in surgery (STROCSS) guideline: an update for the age of Artificial Intelligence","volume":"10","author":"Agha RA","year":"2025","journal-title":"Premier J Sci"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2022.0051"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(24)00198-5"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.16868"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2025.02.011"}],"container-title":["Colorectal 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