{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:47:23Z","timestamp":1787014043254,"version":"build-2736575974"},"reference-count":50,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Recurrent diverticulitis after resection remains a key concern despite advances in minimally invasive surgery. These recurrences may result from incomplete resection of the diseased segment, unrecognized synchronous diverticulosis or ongoing alterations in colonic motility and microbiome composition. This systematic review and single\u2010arm meta\u2010analysis aimed to estimate long\u2010term recurrence and stoma rates following elective surgery for left\u2010sided diverticulitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Following PRISMA guidelines and PROSPERO registration, PubMed, Cochrane and Scopus databases were searched (2000\u20132025) for studies reporting recurrence after elective resection. Single\u2010arm meta\u2010analysis of proportions was performed using random\u2010effects models. Quality was assessed using the JBI Checklist, while subgroup and sensitivity analyses explored heterogeneity. A comparative meta\u2010analysis with medical treatment was not performed due to selection bias, crossover and lack of standardized non\u2010operative protocols.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty\u2010four studies (7,525 patients; mean follow\u2010up 53\u2009months) were included. Pooled recurrence rate was 6.2% (95% CI: 4.8\u20138.0%;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200980.6%), with no difference between RCTs (6.3%) and observational studies (6.1%) or complicated vs. uncomplicated disease. Stoma rate (16 studies, 6,400 patients) was 17.1% (95% CI: 8.4\u201331.9%;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200999.3%), significantly higher in complicated (31.0%) than uncomplicated (5.5%) cases (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.009) and significantly lower post\u20102020 (8.0% vs. 31.2%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003). Quality was high in 92% of studies, while sensitivity analyses confirmed robustness.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Surgical resection achieves durable control with low recurrence and stoma rates. Research priorities include standardized definitions of recurrence, assessing long\u2010term QOL and exploring microbiome influences to refine patient selection and minimize residual risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/codi.70368","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T14:11:33Z","timestamp":1768227093000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Recurrent left\u2010sided diverticulitis after surgery: A systematic review and single arm meta\u2010analysis"],"prefix":"10.1111","volume":"28","author":[{"given":"Richard","family":"Sassun","sequence":"first","affiliation":[{"name":"General Surgery Residency Program, University of Milan  Milan Italy"},{"name":"Division of General Surgery Pio XI Hospital  Desio MB Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3191-4369","authenticated-orcid":false,"given":"Francesco","family":"Brucchi","sequence":"additional","affiliation":[{"name":"Division of General Surgery Pio XI Hospital  Desio MB Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annaclara","family":"Sileo","sequence":"additional","affiliation":[{"name":"Division of General Surgery Pio XI Hospital  Desio MB Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Vignati","sequence":"additional","affiliation":[{"name":"General Surgery Residency Program, University of Milan  Milan Italy"},{"name":"Division of General Surgery Pio XI Hospital  Desio MB Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacopo","family":"Crippa","sequence":"additional","affiliation":[{"name":"Department of General Surgery Vizzolo Predabissi Hospital, ASST Melegnano e Martesana  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9021-9521","authenticated-orcid":false,"given":"Pietro","family":"Achilli","sequence":"additional","affiliation":[{"name":"Department of Mini\u2010Invasive Surgery Grande Ospedale Metropolitano Niguarda  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dario","family":"Maggioni","sequence":"additional","affiliation":[{"name":"General Surgery Residency Program, University of Milan  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonino","family":"Spinelli","sequence":"additional","affiliation":[{"name":"IRCCS Humanitas Research Hospital  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isacco","family":"Montroni","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery National Institute of Tumor  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander T.","family":"Hawkins","sequence":"additional","affiliation":[{"name":"Division of General Surgery, Section of Colon &amp; Rectal Surgery Vanderbilt University Medical Center  Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulio","family":"Mari","sequence":"additional","affiliation":[{"name":"General Surgery Residency Program, University of Milan  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,12]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.CPSURG.2020.100862"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/JAMA.2025.10234"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/S00464\u2010025\u201011754\u2010W"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/J.GASTRO.2020.09.059"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/S00384\u2010023\u201004454\u20101"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000003639"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/WJS.12065"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/S00384\u2010017\u20102766\u2010Z"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2018.12.033"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1245\/S10434\u2010025\u201018642\u20106"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.4103\/JMAS.JMAS_284_24"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.7326\/M21\u20101646"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2018.08.009"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/BMJ.N71"},{"key":"e_1_2_11_16_1","unstructured":"JBI.JBI Critical Appraisal Tools. 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