{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T05:40:49Z","timestamp":1776750049766,"version":"3.51.2"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T00:00:00Z","timestamp":1774742400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T00:00:00Z","timestamp":1774742400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Colorectal Disease"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Precision colon cancer surgery increasingly aims to tailor the extent of resection to individual tumour biology and lymphatic drainage, guided by pre\u2010operative assessment. However, at the hepatic flexure (HF), reproducible pre\u2010operative localisation remains challenging because the HF is not a discrete anatomical point but a transition zone. Misclassification at the HF is not merely semantic: given non\u2010trivial intermediate and central nodal metastasis rates in this region, inconsistent localisation may influence assumptions about regional nodal basins and the adequacy of mesenteric excision and lymphadenectomy. We propose mapping the HF as a bounded transition zone defined by two reproducible, pre\u2010operatively appreciable landmarks, rather than an ill\u2010defined \u2018turn\u2019. This pragmatic framework may better align multidisciplinary planning with true lymphovascular territory and increase the proportion of patients receiving appropriately targeted lymphovascular resection.<\/jats:p>","DOI":"10.1111\/codi.70442","type":"journal-article","created":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T03:40:54Z","timestamp":1774842054000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hepatic flexure: The end of the beginning, or the beginning of the end? Why pre\u2010operative localisation remains inconsistent"],"prefix":"10.1111","volume":"28","author":[{"given":"Krishanth","family":"Naidu","sequence":"first","affiliation":[{"name":"John Goligher Colorectal Unit St James's University Hospital  Leeds UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikolaj","family":"Kowal","sequence":"additional","affiliation":[{"name":"John Goligher Colorectal Unit St James's University Hospital  Leeds UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Diamond","sequence":"additional","affiliation":[{"name":"Department of Radiology St James's University Hospital  Leeds UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9895-9874","authenticated-orcid":false,"given":"Damian","family":"Tolan","sequence":"additional","affiliation":[{"name":"Department of Radiology St James's University Hospital  Leeds UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jim","family":"Tiernan","sequence":"additional","affiliation":[{"name":"John Goligher Colorectal Unit St James's University Hospital  Leeds UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,29]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ans.18434"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1308\/rcsann.2016.0257"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3348\/jksr.2021.0189"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1308\/003588415X14181254790527"},{"issue":"7","key":"e_1_2_7_6_1","first-page":"835","article-title":"Standardizing the definition of each colon cancer segment: Delphi consensus on clinical decision\u2010making for oncologic outcomes","volume":"68","author":"Kuzu MA","year":"2025","journal-title":"Dis Colon Rectum"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12216822"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20180538"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13304-021-01180-7"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.esmogo.2025.100231"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-023-10669-w"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanwpc.2022.100680"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/17562848231160625"},{"issue":"10","key":"e_1_2_7_14_1","article-title":"Comparative accuracy of colonoscopy, computed tomography (CT), and magnetic resonance imaging (MRI) for the preoperative localization of colorectal cancer: a prospective cohort study","volume":"17","author":"Sarafi A","year":"2025","journal-title":"Cureus"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics14192190"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1067\/j.cpsurg.2018.07.001"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13244-025-02116-0"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-023-02789-z"}],"container-title":["Colorectal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.70442","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/codi.70442","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/codi.70442","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T05:01:55Z","timestamp":1776747715000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/codi.70442"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,29]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1111\/codi.70442"],"URL":"https:\/\/doi.org\/10.1111\/codi.70442","archive":["Portico"],"relation":{},"ISSN":["1462-8910","1463-1318"],"issn-type":[{"value":"1462-8910","type":"print"},{"value":"1463-1318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,29]]},"assertion":[{"value":"2026-02-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70442"}}