{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T12:44:13Z","timestamp":1777293853923,"version":"3.51.4"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,1,9]],"date-time":"2013-01-09T00:00:00Z","timestamp":1357689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Physio Funct Imaging"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Whereas ventricular filling has been extensively studied and debated, atrial filling is less well characterized. Therefore, the aim of this study was to quantify atrial filling secured during ventricular diastole and systole, and to investigate whether atrial filling depends on heart rate (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>) and total heart volume (<jats:styled-content style=\"fixed-case\">THV<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty\u2010two athletes (16 women) and 32 normal subjects (16 women) underwent cardiac magnetic resonance imaging. Cardiac volumes and atrioventricular plane displacement (<jats:styled-content style=\"fixed-case\">AVPD<\/jats:styled-content>) were determined. Longitudinal and radial contribution to stroke volume was calculated using planimetry and used to determine diastolic and systolic atrial filling.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Atrial filling during ventricular diastole was 29\u00a0\u00b1\u00a010% of the total stroke volume, and during ventricular systole atrial filling was 68\u00a0\u00b1\u00a08% of the total stroke volume. There were no differences between groups of different <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> (<jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b770 and <jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b741 for diastolic and systolic filling, respectively) or <jats:styled-content style=\"fixed-case\">THV<\/jats:styled-content> (<jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b744 and <jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b746 for diastolic and systolic filling, respectively). Systolic atrial filling was strongly correlated to longitudinal ventricular pumping (R\u00a0=\u00a00\u00b776, <jats:italic>P<\/jats:italic>&lt;0\u00b7001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study demonstrated that in healthy humans at rest, approximately 30% of the total stroke volume enters the atria during ventricular diastole and approximately 70% during systole, independent of heart rate (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>) or heart size. The atria are filled through suction driven by ventricular longitudinal contraction which aspirates blood from the pulmonary and caval veins. As 70% of the atrial filling occurs during ventricular emptying, the heart volume remains relatively constant over the cardiac cycle, which minimizes pulling on surrounding tissues and therefore optimizes energy expenditure.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cpf.12020","type":"journal-article","created":{"date-parts":[[2013,1,9]],"date-time":"2013-01-09T18:35:27Z","timestamp":1357756527000},"page":"233-240","source":"Crossref","is-referenced-by-count":42,"title":["Atrial aspiration from pulmonary and caval veins is caused by ventricular contraction and secures 70% of the total stroke volume independent of resting heart rate and heart size"],"prefix":"10.1111","volume":"33","author":[{"given":"K.","family":"Steding\u2010Ehrenborg","sequence":"first","affiliation":[{"name":"Department of Clinical Physiology Lund University Sk\u00e5ne University Hospital Lund Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Carlsson","sequence":"additional","affiliation":[{"name":"Department of Clinical Physiology Lund University Sk\u00e5ne University Hospital Lund Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Stephensen","sequence":"additional","affiliation":[{"name":"Department of Clinical Physiology Lund University Sk\u00e5ne University Hospital Lund Lund Sweden"},{"name":"Department of Paediatric Cardiology Sk\u00e5ne University Hospital Lund Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Arheden","sequence":"additional","affiliation":[{"name":"Department of Clinical Physiology Lund University Sk\u00e5ne University Hospital Lund Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,1,9]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00354-9"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.184461"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/10976640009148691"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00249.2003"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00969.2003"},{"key":"e_1_2_10_7_1","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1152\/ajplegacy.1954.176.3.423","article-title":"Cardiac variations in venous return studied with a new bristle flowmeter","volume":"176","author":"Brecher GA","year":"1954","journal-title":"Am J Physiol"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.6.5.554"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2281.2001.00356.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01125.2003"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01376.2006"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01148.2006"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00942.2011"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-14-51"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.07.116"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00404.2004"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.78.3.661"},{"key":"e_1_2_10_18_1","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1152\/physrev.1955.35.1.143","article-title":"Volume changes of the left ventricle during blood pooling and exercise in the intact animal; 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