{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T13:27:45Z","timestamp":1773408465618,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,5,28]],"date-time":"2013-05-28T00:00:00Z","timestamp":1369699200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Physio Funct Imaging"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Previous studies reported the relationship between significant blood pressure difference (\u0394<jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>) and early atherosclerotic markers. Although it is known that body temperature is associated with <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> and blood flow, as measured on Korotkoff sound graph (<jats:styled-content style=\"fixed-case\">KSG<\/jats:styled-content>), as well as heart rate and sympathetic nerve activity, it remains unclear whether moderate fever (\u226537\u00b75\u00b0C) can be caused by significant \u0394<jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>. \u0394<jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> was calculated by subtracting the <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> of the left arm from that of the right arm. The aim of our study was to investigate whether an association exists among \u0394<jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>, body temperature, hypertension and <jats:styled-content style=\"fixed-case\">KSG<\/jats:styled-content> area ratio in 1802 new outpatients examined in a seated position in routine clinical practice. Our study documented that absolute systolic blood pressure difference (|\u0394<jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content>|) \u2265\u00a010\u00a0mmHg (observed in 14\u00b76% of the patients) was associated with a significantly higher heart rate, moderate fever, tachycardia and hypertension. In multivariate analysis, the odds ratios (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>s) of |\u0394<jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content>|\u00a0\u2265\u00a010\u00a0mmHg showed significant associated markers of body temperature and hypertension, while the <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>s of <jats:styled-content style=\"fixed-case\">KSG<\/jats:styled-content> area ratio\u00a0\u2265\u00a0170% showed significant associated markers of sex, age, body temperature, hypertension, diabetes mellitus, prior vascular event and smoking. In conclusion, our study of new outpatients in the department of primary care demonstrated that |\u0394<jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content>|\u00a0\u2265\u00a010\u00a0mmHg and <jats:styled-content style=\"fixed-case\">KSG<\/jats:styled-content> area ratio\u00a0\u2265\u00a0170% were associated with moderate fever and hypertension. Furthermore, our study suggests that the association of moderate fever with |\u0394<jats:styled-content style=\"fixed-case\">SBP<\/jats:styled-content>|\u00a0\u2265\u00a010\u00a0mmHg and <jats:styled-content style=\"fixed-case\">KSG<\/jats:styled-content> area ratio\u00a0\u2265\u00a0170% is physiologic as well as pathologic.<\/jats:p>","DOI":"10.1111\/cpf.12050","type":"journal-article","created":{"date-parts":[[2013,5,28]],"date-time":"2013-05-28T06:33:03Z","timestamp":1369722783000},"page":"441-449","source":"Crossref","is-referenced-by-count":3,"title":["A study of the association with blood pressure difference causing body temperature \u226537\u00b75\u00b0C and hypertension in department of primary care"],"prefix":"10.1111","volume":"33","author":[{"given":"Maeda","family":"Shinji","sequence":"first","affiliation":[{"name":"Department of Biostatistics School of Public Health The University of Tokyo Tokyo Japan"},{"name":"Department of General Medicine Harasanshin Hospital Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,5,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2008.11.009"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.hjh.0000170376.23461.f7"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(97)00059-0"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jhh.1001224"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jhh.1002093"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/fampra\/cmm035"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)61710-8"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.167.4.388"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1291\/hypres.28.1"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.84.3.385"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.4085\/1062-6050-47.2.184"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2004.0262b.x"},{"key":"e_1_2_8_14_1","first-page":"3","article-title":"The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2009)","volume":"32","author":"Japanese Society of Hypertension Committee","year":"2009","journal-title":"Hypertens Res"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/00140130903067805"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/10641963.2011.618198"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.4097\/kjae.2010.58.1.91"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200412000-00009"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7004"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200206000-00019"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00498.2011"},{"key":"e_1_2_8_22_1","first-page":"9","article-title":"Utility of Korotkoff sound graph area ratio to be objectively assessed by pulse diagnosis \u201cstrength of a pulse\u201d in physical findings of oriental medicine","volume":"18","author":"Maeda S","year":"2012","journal-title":"J Jpn Mibyou Syst Assoc"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/1753944707087409"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000097770.66965.2A"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2011.04.009"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/28.6.537"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1197\/aemj.9.4.342"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000154900.76284.F6"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2008.01756.x"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1995.06010058.x"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800810208"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2010.204461"},{"key":"e_1_2_8_33_1","unstructured":"TomitaM inventor.Apparatus for detecting and displaying blood circulatory information. 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