{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T06:07:10Z","timestamp":1791526030206,"version":"4.3.4"},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,11,7]],"date-time":"2013-11-07T00:00:00Z","timestamp":1383782400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008749","name":"American College of Sports Medicine","doi-asserted-by":"crossref","award":["ACSM 2012-03468"],"award-info":[{"award-number":["ACSM 2012-03468"]}],"id":[{"id":"10.13039\/100008749","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Physio Funct Imaging"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Blood flow restriction (<jats:styled-content style=\"fixed-case\">BFR<\/jats:styled-content>) exercise may be an alternative form of resistance training; however, a side of effect of <jats:styled-content style=\"fixed-case\">BFR<\/jats:styled-content> resistance exercise is acute muscle pain. Typically, <jats:styled-content style=\"fixed-case\">BFR<\/jats:styled-content> exercise studies restrict blood flow with a cuff continuously during the exercise bout, including rest periods. However, others have used intermittent <jats:styled-content style=\"fixed-case\">BFR<\/jats:styled-content> where the cuff is inflated only during sets. We performed two studies to compare intermittent and continuous <jats:styled-content style=\"fixed-case\">BFR<\/jats:styled-content> exercise. In study one, eleven subjects randomly proceeded through three treatments of unilateral leg extensions to failure: (i) continuous <jats:styled-content style=\"fixed-case\">BFR<\/jats:styled-content>, (ii) intermittent <jats:styled-content style=\"fixed-case\">BFR<\/jats:styled-content> and (iii) control (exercise without <jats:styled-content style=\"fixed-case\">BFR<\/jats:styled-content>). Pain measurements were taken immediately after each set. In study two, subjects (<jats:italic>n\u00a0<\/jats:italic>=\u00a032) underwent a 5\u2010week resistance training programme after random assignment to one of the three conditions. Lean mass and strength were assessed at baseline and after training. Continuous <jats:styled-content style=\"fixed-case\">BFR<\/jats:styled-content> resulted in significantly greater pain than intermittent <jats:styled-content style=\"fixed-case\">BFR<\/jats:styled-content> or control. Both <jats:styled-content style=\"fixed-case\">BFR<\/jats:styled-content> conditions resulted in significantly fewer repetitions to failure than control. This suggests that an acute bout of intermittent <jats:styled-content style=\"fixed-case\">BFR<\/jats:styled-content> exercise may produce as much muscle fatigue as an acute bout of continuous <jats:styled-content style=\"fixed-case\">BFR<\/jats:styled-content> exercise, but with less pain. With training, maximal knee extension (<jats:italic>P\u00a0<\/jats:italic>=\u00a00\u00b7033) and maximum knee flexion (<jats:italic>P\u00a0<\/jats:italic>=\u00a00\u00b7007) strength increased among all groups. There were no significant differences between groups in strength or lean mass. These results suggest that short\u2010term low\u2010load resistance training increases muscle strength to a similar extent as low\u2010load resistance training without <jats:styled-content style=\"fixed-case\">BFR<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/cpf.12100","type":"journal-article","created":{"date-parts":[[2014,4,18]],"date-time":"2014-04-18T11:05:11Z","timestamp":1397819111000},"page":"356-363","source":"Crossref","is-referenced-by-count":70,"title":["Perceptual effects and efficacy of intermittent or continuous blood flow restriction resistance training"],"prefix":"10.1111","volume":"34","author":[{"given":"P. J.","family":"Fitschen","sequence":"first","affiliation":[{"name":"Division of Nutritional Sciences University of Illinois Urbana IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. M.","family":"Kistler","sequence":"additional","affiliation":[{"name":"Department of Kinesiology and Community Health University of Illinois Urbana IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. H.","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Kinesiology and Community Health University of Illinois Urbana IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. R.","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Kinesiology and Community Health University of Illinois Urbana IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. T.","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Kinesiology and Community Health University of Illinois Urbana IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. J.","family":"Walsh","sequence":"additional","affiliation":[{"name":"Department of Kinesiology and Community Health University of Illinois Urbana IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. R.","family":"Wilund","sequence":"additional","affiliation":[{"name":"Division of Nutritional Sciences University of Illinois Urbana IL USA"},{"name":"Department of Kinesiology and Community Health University of Illinois Urbana IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,11,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3806\/ijktr.1.6"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0b013e3181915670"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0012033"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1249\/01.MSS.0000074458.71025.71"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0838.2010.01100.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-199708000-00004"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/02640414.2010.485647"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01266.2009"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0838.2010.01260.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-989405"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1268472"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-011-2266-8"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/17461391.2010.551420"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2011.07.029"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2011.10.014"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1249\/mss.0b013e31815c6d7e"},{"key":"e_1_2_7_18_1","first-page":"918","article-title":"Determining the magnitude of treatment effects in strength training research through the use of the effect size","volume":"18","author":"Rhea MR","year":"2004","journal-title":"J Strength Cond Res"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00429076"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsams.2007.09.009"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00149.2012"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.2000.88.6.2097"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.2000.88.1.61"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-001-0561-5"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.2170\/jjphysiol.54.585"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0b013e31827ddb1f"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1519\/R-16884.1"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1519\/JSC.0b013e3181bc1c2a"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-097X.2010.00949.x"}],"container-title":["Clinical Physiology and Functional Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcpf.12100","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cpf.12100","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T10:44:07Z","timestamp":1696329847000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cpf.12100"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,7]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["10.1111\/cpf.12100"],"URL":"https:\/\/doi.org\/10.1111\/cpf.12100","archive":["Portico"],"relation":{},"ISSN":["1475-0961","1475-097X"],"issn-type":[{"value":"1475-0961","type":"print"},{"value":"1475-097X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,7]]}}}