{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T06:02:12Z","timestamp":1760853732259},"reference-count":70,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,11,24]],"date-time":"2013-11-24T00:00:00Z","timestamp":1385251200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Physio Funct Imaging"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Positron emission tomography (<jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>)\/computed tomography (<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>) is not suited for primary diagnostics of breast tumours and it cannot replace sentinel lymph node technique in determining metastases to the axilla. <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> has a high sensitivity and specificity regarding the detection of loco\u2010regional recurrence and metastases to mediastinal and internal mammary lymph nodes, as well as distant metastases. Whether the method can replace conventional methods, or be a supplement when this is non\u2010conclusive, remains unresolved. <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> cannot be recommended for routine follow\u2010up but is recommended in patients with suspected relapse when conventional imaging has given equivocal results. <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> can be applied to confirm isolated loco\u2010regional relapse or metastatic lesion detected by conventional imaging. <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> has a high sensitivity for detecting response to treatment, but a low specificity calls for cautions. Further investigations into the use of <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> to predict and monitor response are warranted, before this approach may find its way into a clinical setting. In the future, <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> will probably find increasing use in treatment planning and evaluation of patients with breast cancer.<\/jats:p>","DOI":"10.1111\/cpf.12106","type":"journal-article","created":{"date-parts":[[2013,11,25]],"date-time":"2013-11-25T10:49:49Z","timestamp":1385376589000},"page":"426-433","source":"Crossref","is-referenced-by-count":7,"title":["Clinical application of <sup>18<\/sup>F\u2010fluoro\u20102\u2010deoxy\u2010<scp>D<\/scp>\u2010glucose positron emission tomography\/computed tomography in breast cancer"],"prefix":"10.1111","volume":"34","author":[{"given":"M.","family":"Bernsdorf","sequence":"first","affiliation":[{"name":"Department of Oncology Copenhagen University Hospital Rigshospitalet Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Graff","sequence":"additional","affiliation":[{"name":"Department of Clinical Physiology and Nuclear Medicine Copenhagen University Hospital Hvidovre Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,11,24]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/02841851.2010.501342"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24534"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2009.11.009"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2010.07.034"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2000.18.20.3495"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mds002"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-007-0459-5"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1258\/ar.2012.110699"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25727"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1258\/ar.2012.110603"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/56324742"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002590050319"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2008.10.031"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-10-2649"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2011.08.002"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-010-1626-7"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2012.12.027"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/MNM.0b013e328341c898"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.5858\/2000-124-0966-PFIBC"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11307-005-0013-4"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.17.1496"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2011.09.002"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-010-1494-1"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdt004"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6459"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2010.04.029"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2008.02.056"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.111.093864"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.111.094045"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28020"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1258\/ar.2012.110420"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.rct.0000284394.83696.42"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10147-010-0120-3"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/93330765"},{"key":"e_1_2_5_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2010.05.021"},{"key":"e_1_2_5_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-011-1442-1"},{"key":"e_1_2_5_38_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-11-452"},{"key":"e_1_2_5_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-011-1832-4"},{"key":"e_1_2_5_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-011-1767-9"},{"key":"e_1_2_5_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-006-9159-2"},{"key":"e_1_2_5_42_1","doi-asserted-by":"publisher","DOI":"10.1097\/MNM.0b013e3283516716"},{"key":"e_1_2_5_43_1","first-page":"135","article-title":"The role of (18)F\u2010FDG PET\/CT in initial staging of patients with locally advanced breast carcinoma with an emphasis on M staging","volume":"14","author":"Mittal BR","year":"2011","journal-title":"Hell J Nucl Med"},{"key":"e_1_2_5_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-011-1981-z"},{"key":"e_1_2_5_45_1","doi-asserted-by":"publisher","DOI":"10.1258\/ar.2011.110245"},{"key":"e_1_2_5_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-010-1529-7"},{"key":"e_1_2_5_47_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2011-0089"},{"key":"e_1_2_5_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2004.03.012"},{"key":"e_1_2_5_49_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-011-2236-x"},{"key":"e_1_2_5_50_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.179.5.1791193"},{"key":"e_1_2_5_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.22362"},{"key":"e_1_2_5_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-010-0771-9"},{"key":"e_1_2_5_53_1","doi-asserted-by":"publisher","DOI":"10.3310\/hta14500"},{"key":"e_1_2_5_54_1","doi-asserted-by":"publisher","DOI":"10.1097\/RLU.0b013e31805375e0"},{"key":"e_1_2_5_55_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.38.1103"},{"key":"e_1_2_5_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22292"},{"key":"e_1_2_5_57_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-012-2077-0"},{"key":"e_1_2_5_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-011-1735-y"},{"key":"e_1_2_5_59_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-010-1588-9"},{"key":"e_1_2_5_60_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002590000448"},{"key":"e_1_2_5_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2007.10.021"},{"key":"e_1_2_5_62_1","doi-asserted-by":"publisher","DOI":"10.1186\/bcr2591"},{"key":"e_1_2_5_63_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4741.2010.00987.x"},{"key":"e_1_2_5_64_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.111.098640"},{"key":"e_1_2_5_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2005.06.029"},{"key":"e_1_2_5_66_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.12111177"},{"key":"e_1_2_5_67_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11307-009-0294-0"},{"key":"e_1_2_5_68_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/17395663"},{"key":"e_1_2_5_69_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2001.19.6.1688"},{"key":"e_1_2_5_70_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-011-1780-z"},{"key":"e_1_2_5_71_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-007-9671-z"}],"container-title":["Clinical Physiology and Functional Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcpf.12106","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cpf.12106","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T19:49:32Z","timestamp":1696362572000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cpf.12106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,24]]},"references-count":70,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["10.1111\/cpf.12106"],"URL":"https:\/\/doi.org\/10.1111\/cpf.12106","archive":["Portico"],"relation":{},"ISSN":["1475-0961","1475-097X"],"issn-type":[{"value":"1475-0961","type":"print"},{"value":"1475-097X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,24]]}}}