{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T21:00:10Z","timestamp":1740171610691,"version":"3.37.3"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,2,16]],"date-time":"2014-02-16T00:00:00Z","timestamp":1392508800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007048","name":"Mayo Foundation","doi-asserted-by":"crossref","award":["CR20"],"award-info":[{"award-number":["CR20"]}],"id":[{"id":"10.13039\/100007048","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Physio Funct Imaging"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>To evaluate the effect of positive end\u2010expiratory pressure (<jats:styled-content style=\"fixed-case\">PEEP<\/jats:styled-content>) on sound propagation through injured lungs, we injected a multifrequency broad\u2010band sound signal into the airway of eight anesthetized, intubated and mechanically ventilated pigs, while recording transmitted sound at three locations bilaterally on the chest wall. Oleic acid injections effected a severe pulmonary oedema predominately in the dependent lung regions, with an average increase in venous admixture from 19\u00a0\u00b1\u00a015 to 59\u00a0\u00b1\u00a014% (<jats:italic>P<\/jats:italic>&lt;0\u00b7001), and a reduction in dynamic respiratory system compliance from 34\u00a0\u00b1\u00a07 to 14\u00a0\u00b1\u00a04\u00a0ml\u00a0cmH<jats:sub>2<\/jats:sub>O<jats:sup>\u22121<\/jats:sup> (<jats:italic>P<\/jats:italic>&lt;0\u00b7001). A concomitant decrease in sound transit time was seen in the dependent lung regions (<jats:italic>P<\/jats:italic>&lt;0\u00b705); no statistically significant change occurred in the lateral or non\u2010dependent areas. The application of <jats:styled-content style=\"fixed-case\">PEEP<\/jats:styled-content> resulted in a decrease in venous admixture, increase in respiratory system compliance and return of the sound transit time to pre\u2010injury levels in the dependent lung regions. Our results indicate that sound transmission velocity increases in lung tissue affected by permeability\u2010type pulmonary oedema in a manner reversible during alveolar recruitment with <jats:styled-content style=\"fixed-case\">PEEP<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/cpf.12138","type":"journal-article","created":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T11:32:12Z","timestamp":1392636732000},"page":"134-141","source":"Crossref","is-referenced-by-count":4,"title":["Effect of positive end\u2010expiratory pressure on acoustic wave propagation in experimental porcine lung injury"],"prefix":"10.1111","volume":"35","author":[{"given":"Jukka","family":"R\u00e4s\u00e4nen","sequence":"first","affiliation":[{"name":"Department of Anesthesiology H. Lee Moffitt Cancer Center Tampa FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael E.","family":"Nemergut","sequence":"additional","affiliation":[{"name":"Departments of Anesthesiology and Pediatrics Mayo Foundation for Education and Research Rochester MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noam","family":"Gavriely","sequence":"additional","affiliation":[{"name":"Technion \u2013 Israel Institute of Technology Rappaport Faculty of Medicine Haifa Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,2,16]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001340050585"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00683.2004"},{"key":"e_1_2_7_4_1","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1152\/japplphysiol.00050.2002","article-title":"Sound transmission in the lungs as a function of lung volume","volume":"93","author":"Bergstresser T","year":"2003","journal-title":"J Appl Physiol"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199101000-00004"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1011491231934"},{"key":"e_1_2_7_7_1","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1152\/jappl.1989.66.1.278","article-title":"Transmission to the chest of sound introduced at the mouth","volume":"66","author":"Kraman SS","year":"1989","journal-title":"J Appl Physiol"},{"key":"e_1_2_7_8_1","doi-asserted-by":"crossref","first-page":"2472","DOI":"10.1152\/jappl.2000.89.6.2472","article-title":"Sound transmission between 50 and 600\u00a0Hz in excised pig lungs filied with air and helium","volume":"89","author":"Leung A","year":"2000","journal-title":"J Appl Physiol"},{"key":"e_1_2_7_9_1","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1152\/japplphysiol.00568.2002","article-title":"Transpulmonary speed of sound input into the supraclavicular space","volume":"94","author":"Paciej B","year":"2003","journal-title":"J Appl Physiol"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.149.1.8111603"},{"key":"e_1_2_7_11_1","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1152\/jappl.1989.66.5.2061","article-title":"Early detection of pulmonary congestion and edema in dogs by using lung sounds","volume":"66","author":"Ploysongsang Y","year":"1989","journal-title":"J Appl Physiol"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01238.2001"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-005-2745-7"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1109\/TBME.2006.875667"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00651.2013"},{"key":"e_1_2_7_16_1","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1152\/jappl.1983.54.1.304","article-title":"Sound speed in pulmonary parenchyma","volume":"54","author":"Rice D","year":"1983","journal-title":"J Appl Physiol"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199805000-00027"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-097X.2005.00652.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-011-2291-4"}],"container-title":["Clinical Physiology and Functional Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcpf.12138","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cpf.12138","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T17:54:13Z","timestamp":1696355653000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cpf.12138"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,16]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.1111\/cpf.12138"],"URL":"https:\/\/doi.org\/10.1111\/cpf.12138","archive":["Portico"],"relation":{},"ISSN":["1475-0961","1475-097X"],"issn-type":[{"type":"print","value":"1475-0961"},{"type":"electronic","value":"1475-097X"}],"subject":[],"published":{"date-parts":[[2014,2,16]]}}}