{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T07:14:14Z","timestamp":1696317254356},"reference-count":39,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,12,2]],"date-time":"2015-12-02T00:00:00Z","timestamp":1449014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Physio Funct Imaging"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Computed tomography (<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>) is a novel method for assessment of myocardial perfusion and has not yet been compared to rubidium\u201082 positron emission tomography (<jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>). We aimed to compare <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> measured semi\u2010quantitative myocardial perfusion with absolute quantified myocardial perfusion using <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content> and to detect stenotic territories in patients with severe coronary artery disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Eighteen patients with stenosis narrowing coronary arteries \u226570% demonstrated on invasive coronary angiography underwent rest and adenosine stress imaging obtained by 320\u2010multidetector <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> scanner and <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content> 64\u2010slice scanner. <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> measured myocardial attenuation density (<jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>) and perfusion index (<jats:styled-content style=\"fixed-case\">PI<\/jats:styled-content>) were correlated to absolute <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content> myocardial perfusion values.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Rest <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>, rest and stress <jats:styled-content style=\"fixed-case\">PI<\/jats:styled-content> did not correlate to <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content> findings (<jats:italic>r<\/jats:italic>\u00a0=\u00a00\u00b7412, <jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b7113; <jats:italic>r<\/jats:italic>\u00a0=\u00a00\u00b7300, <jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b7259; and <jats:italic>r<\/jats:italic>\u00a0=\u00a00\u00b7508, <jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b7064, respectively). However, there was a significant correlation between stress <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content> and stress <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content> values (<jats:italic>r<\/jats:italic>\u00a0=\u00a00\u00b7670, <jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b7009) and between stress and rest differences for <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PI<\/jats:styled-content>\u00a0with <jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content> differences (<jats:italic>r<\/jats:italic>\u00a0=\u00a00\u00b7620, <jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b7006; and <jats:italic>r<\/jats:italic>\u00a0=\u00a00\u00b7639, <jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b7004, respectively). Furthermore, significant differences were observed between remote and\u00a0stenotic territories for rest and stress <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content> (48\u00a0\u00b1\u00a014<jats:styled-content style=\"fixed-case\">HU<\/jats:styled-content> and 37\u00a0\u00b1\u00a016<jats:styled-content style=\"fixed-case\">HU<\/jats:styled-content>,<jats:italic> P<\/jats:italic>\u00a0=\u00a00\u00b7002; 76\u00a0\u00b1\u00a019<jats:styled-content style=\"fixed-case\">HU<\/jats:styled-content> and 58\u00a0\u00b1\u00a013<jats:styled-content style=\"fixed-case\">HU<\/jats:styled-content>,<jats:italic> P<\/jats:italic>&lt;0\u00b7001, respectively), <jats:styled-content style=\"fixed-case\">PI<\/jats:styled-content> (9\u00b76\u00a0\u00b1\u00a02\u00b79 and\u00a07\u00b75\u00a0\u00b1\u00a03\u00b71,\u00a0<jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b7002; 21\u00b76\u00a0\u00b1\u00a04\u00b71 and 16\u00b79\u00a0\u00b1\u00a03\u00b79, <jats:italic>P<\/jats:italic>&lt;0\u00b7001, respectively) and\u00a0<jats:styled-content style=\"fixed-case\">PET<\/jats:styled-content>\u00a0(0\u00b796\u00a0\u00b1\u00a00\u00b737\u00a0ml\u00a0g<jats:sup>\u22121<\/jats:sup>\u00a0min<jats:sup>\u22121<\/jats:sup> and 0\u00b786\u00a0\u00b1\u00a00\u00b726\u00a0ml\u00a0g<jats:sup>\u22121<\/jats:sup>\u00a0min<jats:sup>\u22121<\/jats:sup>, <jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b7036;\u00a02\u00b707\u00a0\u00b1\u00a00\u00b776\u00a0ml\u00a0g<jats:sup>\u22121<\/jats:sup>\u00a0min<jats:sup>\u22121<\/jats:sup> and 1\u00b761\u00a0\u00b1\u00a00\u00b776\u00a0ml\u00a0g<jats:sup>\u22121<\/jats:sup>\u00a0min<jats:sup>\u22121<\/jats:sup>, <jats:italic>P<\/jats:italic>\u00a0= 0\u00b7006, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Semi\u2010quantitative <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> parameters may be useful in the detection of myocardium subtended by stenotic coronary arteries.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cpf.12322","type":"journal-article","created":{"date-parts":[[2015,12,2]],"date-time":"2015-12-02T07:53:28Z","timestamp":1449042808000},"page":"481-488","source":"Crossref","is-referenced-by-count":4,"title":["Semi\u2010quantitative myocardial perfusion measured by computed tomography in patients with refractory angina: a head\u2010to\u2010head comparison with quantitative rubidium\u201082 positron emission tomography as reference"],"prefix":"10.1111","volume":"37","author":[{"given":"Abbas Ali","family":"Qayyum","sequence":"first","affiliation":[{"name":"Department of Cardiology &amp; Cardiac Catheterization Laboratory 2014 The Heart Centre Rigshospitalet University Hospital of Copenhagen and Faculty of Health Sciences Copenhagen University Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f8rgen Tobias","family":"K\u00fchl","sequence":"additional","affiliation":[{"name":"Department of Cardiology &amp; Cardiac Catheterization Laboratory 2014 The Heart Centre Rigshospitalet University Hospital of Copenhagen and Faculty of Health Sciences Copenhagen University Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Kjaer","sequence":"additional","affiliation":[{"name":"Department of Clinical Physiology, Nuclear Medicine &amp; PET Rigshospitalet University Hospital of Copenhagen and Faculty of Health Sciences Copenhagen University Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Hasbak","sequence":"additional","affiliation":[{"name":"Department of Clinical Physiology, Nuclear Medicine &amp; PET Rigshospitalet University Hospital of Copenhagen and Faculty of Health Sciences Copenhagen University Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus Fuglsang","family":"Kofoed","sequence":"additional","affiliation":[{"name":"Department of Cardiology &amp; Cardiac Catheterization Laboratory 2014 The Heart Centre Rigshospitalet University Hospital of Copenhagen and Faculty of Health Sciences Copenhagen University Copenhagen Denmark"},{"name":"Department of Radiology Diagnostic Center Rigshospitalet University Hospital of Copenhagen and Faculty of Health Sciences Copenhagen University Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Kastrup","sequence":"additional","affiliation":[{"name":"Department of Cardiology &amp; Cardiac Catheterization Laboratory 2014 The Heart Centre Rigshospitalet University Hospital of Copenhagen and Faculty of Health Sciences Copenhagen University Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,12,2]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nuclcard.2005.12.004"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/hc0402.102975"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2011.04.015"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2009.04.009"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.09.043"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12350-009-9170-1"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21306"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.04.014"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.111.969303"},{"key":"e_1_2_8_11_1","first-page":"1899","article-title":"A prospective comparison of rubidium\u201082 PET and thallium\u2010201 SPECT myocardial perfusion imaging utilizing a single dipyridamole stress in the diagnosis of coronary artery disease","volume":"31","author":"Go RT","year":"1990","journal-title":"J Nucl Med"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)61335-4"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11604-012-0159-3"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.12.040"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.652016"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.10091399"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.06.066"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.06.020"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-008-0972-1"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-007-0478-2"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/2012.jama.11274"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht296"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.050427"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-010-9676-2"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-013-2788-z"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2014.12.017"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.2217\/rme.12.17"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-013-0234-6"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht488"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-008-1022-x"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs022"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.549170"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.10.3346"},{"key":"e_1_2_8_34_1","first-page":"1602","article-title":"Myocardial viability assessment by PET: (82)Rb defect washout does not predict the results of metabolic\u2010perfusion mismatch","volume":"46","author":"Stankewicz MA","year":"2005","journal-title":"J Nucl Med"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2010.07.011"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199406233302503"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.872358"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)02961-3"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.06.025"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.01.065"}],"container-title":["Clinical Physiology and Functional Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcpf.12322","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcpf.12322","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cpf.12322","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T15:19:52Z","timestamp":1696259992000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cpf.12322"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,2]]},"references-count":39,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["10.1111\/cpf.12322"],"URL":"https:\/\/doi.org\/10.1111\/cpf.12322","archive":["Portico"],"relation":{},"ISSN":["1475-0961","1475-097X"],"issn-type":[{"value":"1475-0961","type":"print"},{"value":"1475-097X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,2]]}}}