{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T18:02:46Z","timestamp":1780596166784,"version":"3.54.1"},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T00:00:00Z","timestamp":1493164800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007756","name":"University of Arkansas","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007756","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Physio Funct Imaging"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Consensus guidelines have attempted to standardize the measurement and interpretation of pulse wave velocity (<jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content>); however, guidelines have not addressed whether hydration status affects <jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content>. Moreover, multiple studies have utilized heat stress to reduce arterial stiffness which may lead to dehydration. This study utilized two experiments to investigate the effects of dehydration on <jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content> at rest and during passive heat stress. In experiment 1, subjects (<jats:italic>n\u00a0<\/jats:italic>=\u00a019) completed two trials, one in which they arrived euhydrated and one dehydrated (1\u00b72[1\u00b70]% body mass loss). In experiment 2, subjects (<jats:italic>n\u00a0<\/jats:italic>=\u00a011) began two trials euhydrated and in one trial did not receive water during heat stress, thus becoming dehydrated (1\u00b76[0\u00b76]% body mass loss); the other trial subjects remained euhydrated. Using Doppler ultrasound, carotid\u2010to\u2010femoral (central) and carotid\u2010to\u2010radial (peripheral) <jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content>s were measured. <jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content> was obtained at a normothermic baseline, and at a 0\u00b75\u00b0C and 1\u00b0C elevation in rectal temperature (via passive heating). In experiment 1, baseline central <jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content> was significantly higher when euhydrated compared to dehydrated (628[95] versus 572[91] cm\u00a0s<jats:sup>\u22121<\/jats:sup>, respectively; <jats:italic>P<\/jats:italic>&lt;0\u00b705), but peripheral <jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content> was unaffected (861[117] versus 825[149] cm\u00a0s<jats:sup>\u22121<\/jats:sup>; <jats:italic>P&gt;<\/jats:italic>0\u00b705). However, starting euhydrated and becoming dehydrated during heating in experiment 2 did not affect <jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content> measures (<jats:italic>P<\/jats:italic>&gt;0\u00b705), and independent of hydration status peripheral <jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content> was reduced when rectal temperature was elevated 0\u00b75\u00b0C (\u221274[45] cm\u00a0s<jats:sup>\u22121<\/jats:sup>; <jats:italic>P<\/jats:italic>&lt;0\u00b705) and 1\u00b70\u00b0C (\u221270[48] cm\u00a0s<jats:sup>\u22121<\/jats:sup>; <jats:italic>P<\/jats:italic>&lt;0\u00b705). Overall, these data suggest that hydration status affects measurements of central <jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content> in normothermic, resting conditions. Therefore, future guidelines should suggest that investigators ensure adequate hydration status prior to measures of <jats:styled-content style=\"fixed-case\">PWV<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/cpf.12436","type":"journal-article","created":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T11:05:46Z","timestamp":1493204746000},"page":"447-454","source":"Crossref","is-referenced-by-count":7,"title":["Hydration status influences the measurement of arterial stiffness"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4541-6283","authenticated-orcid":false,"given":"Aaron R.","family":"Caldwell","sequence":"first","affiliation":[{"name":"Human Performance Laboratory College of Education and Health Professionals University of Arkansas Fayetteville AR USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew A.","family":"Tucker","sequence":"additional","affiliation":[{"name":"Human Performance Laboratory College of 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