{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T22:22:07Z","timestamp":1770675727529,"version":"3.49.0"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,8,9]],"date-time":"2017-08-09T00:00:00Z","timestamp":1502236800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Physio Funct Imaging"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study was to evaluate an extended protocol of the large vessels using high\u2010frequency duplex ultrasound (<jats:styled-content style=\"fixed-case\">DUS<\/jats:styled-content>) for detection of vessel wall inflammation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010eight patients performed a <jats:styled-content style=\"fixed-case\">DUS<\/jats:styled-content> examination where arteritis could not be excluded. All <jats:styled-content style=\"fixed-case\">DUS<\/jats:styled-content> examinations were performed using <jats:styled-content style=\"fixed-case\">ACUSON<\/jats:styled-content> S2000 <jats:styled-content style=\"fixed-case\">TM<\/jats:styled-content> ultrasound system (Siemens Medical Solutions <jats:styled-content style=\"fixed-case\">USA<\/jats:styled-content>, Inc.). High\u2010frequency linear transducers were used (18L6 <jats:styled-content style=\"fixed-case\">MH<\/jats:styled-content>z, 9L4<jats:styled-content style=\"fixed-case\">MH<\/jats:styled-content>z) or curve linear for the aortic arch (6C2\u00a0MHz). Carotid, vertebral, central neck arteries (subclavian, axillary, innominate) arteries, aortic arch and femoral arteries were studied. Circumferential, homogenous wall thickening, with or without a hyperechogenic stripe lining the innermost layer, were regarded as typical signs of arteritis. Intima\u2010media thickness (<jats:styled-content style=\"fixed-case\">IMT<\/jats:styled-content>) was measured in the patients and a normal control group.<\/jats:p><jats:p>The latest clinical updated diagnosis was assessed at least 6\u00a0months after <jats:styled-content style=\"fixed-case\">DUS<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">DUS<\/jats:styled-content> findings showed normal vessels (<jats:italic>n<\/jats:italic>\u00a0=\u00a014), arteritis and atherosclerosis (<jats:italic>n<\/jats:italic>\u00a0=\u00a013), atherosclerosis (<jats:italic>n<\/jats:italic>\u00a0=\u00a015) and arteritis (<jats:italic>n<\/jats:italic>\u00a0=\u00a016). The latter group had a significant increased <jats:styled-content style=\"fixed-case\">IMT<\/jats:styled-content> in the common femoral artery and the common carotid artery (mean 1\u00b70\u00a0\u00b1\u00a0 <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content> 0\u00b73\u00a0mm versus 0\u00b76\u00a0\u00b1\u00a00\u00b72\u00a0mm in the normal group (<jats:italic>n<\/jats:italic>\u00a0=\u00a037), <jats:italic>P<\/jats:italic>&lt;0\u00b700001, 1\u00b72\u00a0\u00b1\u00a00\u00b75\u00a0mm versus 0\u00b78\u00a0\u00b1\u00a00\u00b72\u00a0mm in the normal group (<jats:italic>n<\/jats:italic>\u00a0=\u00a040), <jats:italic>P<\/jats:italic>&lt;0\u00b700001).<\/jats:p><jats:p>In the groups with sonographic signs implying arteritis (<jats:italic>n<\/jats:italic>\u00a0=\u00a029), 20 patients had a clinical diagnosis of arteritis, whereas eight patients had another main diagnosis such as malignancy\/other inflammatory or infectious disease complicated by inflammation of the vessel wall. One patient had multiple diagnoses and was not possible to classify.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>An extended ultrasound protocol for central neck and leg arteries could be of value for diagnosis of arteritis. In case of atypical vessel wall inflammation, other main diagnoses should be considered.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cpf.12450","type":"journal-article","created":{"date-parts":[[2017,8,10]],"date-time":"2017-08-10T04:38:38Z","timestamp":1502339918000},"page":"586-594","source":"Crossref","is-referenced-by-count":10,"title":["An extended high\u2010frequency ultrasound protocol for detection of vessel wall inflammation"],"prefix":"10.1111","volume":"38","author":[{"given":"H.","family":"Zachrisson","sequence":"first","affiliation":[{"name":"Department of Clinical Physiology Department of Medical and Health Sciences Link\u00f6ping University Link\u00f6ping Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Svensson","sequence":"additional","affiliation":[{"name":"Department of Clinical Physiology Department of Medical and Health Sciences Link\u00f6ping University Link\u00f6ping 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