{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T07:46:13Z","timestamp":1778744773987,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,1,24]],"date-time":"2018-01-24T00:00:00Z","timestamp":1516752000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Sheffield Vascular Institute"},{"name":"Sheffield Thoracic Institute"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Physio Funct Imaging"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Lower extremity peripheral arterial disease (<jats:styled-content style=\"fixed-case\">PAD<\/jats:styled-content>) is a chronic condition most commonly presenting with intermittent claudication (<jats:styled-content style=\"fixed-case\">IC<\/jats:styled-content>). Intermittent claudication limits walking ability and may negatively affect health\u2010related quality of life. Treadmill assessment of maximal walking distance (<jats:styled-content style=\"fixed-case\">MWD<\/jats:styled-content>) is the gold standard to assess <jats:styled-content style=\"fixed-case\">PAD<\/jats:styled-content> symptom severity. Despite being a well\u2010established and reproducible tool, it may be inappropriate (due to frailty or fear) for some patients and only describes maximal abilities for a single walk test. Global positioning systems (<jats:styled-content style=\"fixed-case\">GPS<\/jats:styled-content>) have been proposed as reliable and reproducible tool to measure total, mean and maximal walking distances in patients with <jats:styled-content style=\"fixed-case\">PAD<\/jats:styled-content>, in the community setting. Using <jats:styled-content style=\"fixed-case\">GPS<\/jats:styled-content>, our study attempted to explore what happens to the walking ability of patients with <jats:styled-content style=\"fixed-case\">IC<\/jats:styled-content> following no intervention under \u2018real\u2010life\u2019 conditions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design and methods<\/jats:title><jats:p>Using the GlobalSat <jats:styled-content style=\"fixed-case\">DG<\/jats:styled-content>100 <jats:styled-content style=\"fixed-case\">GPS<\/jats:styled-content>, forty\u2010three patients (69\u00a0\u00b1\u00a09\u00a0years; nine female; no invasive interventions or rehabilitation) undertook two 60\u2010min walking assessments, 6\u00a0months apart. Assessments took place in community spaces that had even terrain, no tall trees or buildings and were free from motorized vehicles. Global positioning systems\u2010measured maximum walking distance was the main study outcome measure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Over the 6\u2010month period, patients demonstrated significantly shorter <jats:styled-content style=\"fixed-case\">GPS<\/jats:styled-content>\u2010measured, mean (552\u00a0m versus 334\u00a0m; <jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b702) and maximum (714\u00a0m versus 545\u00a0m; <jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b704) walking distances, stopping also more frequently (nine versus five times; <jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b703).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Given the reported symptom progression, we advocate early intervention (e.g. exercise interventions) combined with frequent patient monitoring in attempts to maintain or improve walking ability.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cpf.12501","type":"journal-article","created":{"date-parts":[[2018,1,25]],"date-time":"2018-01-25T03:12:00Z","timestamp":1516849920000},"page":"889-894","source":"Crossref","is-referenced-by-count":5,"title":["Real\u2010life adaptations in walking patterns in patients with established peripheral arterial disease assessed using a global positioning system in the community: a cohort study"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8864-4403","authenticated-orcid":false,"given":"Markos","family":"Klonizakis","sequence":"first","affiliation":[{"name":"Centre for Sport and Exercise Science Sheffield Hallam University Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen M.","family":"Bianchi","sequence":"additional","affiliation":[{"name":"Academic Directorate of Respiratory Medicine Sheffield Teaching Hospitals Foundation Trust Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Gernigon","sequence":"additional","affiliation":[{"name":"EuroMov Univ. Montpellier Montpellier France"},{"name":"CIAMS Univ. Paris Sud Universit\u00e9 Paris\u2010Saclay Orsay Cedex France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Abraham","sequence":"additional","affiliation":[{"name":"D\u00e9partement de physiologie et explorations fonctionnelles CHU d'Angers Angers France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shah","family":"Nawaz","sequence":"additional","affiliation":[{"name":"Sheffield Vascular Institute Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,1,24]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"1722","article-title":"Systematic review of home\u2010based exercise programmes for individuals with intermittent claudication","volume":"58","author":"Al\u2010Jundi W","year":"2013","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1062-0303(97)90049-2"},{"key":"e_1_2_8_4_1","unstructured":"BeldonP.Practice development How to\u2026Ten top tips for Doppler ABPI (in Wound International Journal(2011).http:\/\/www.wintjournal.com\/media\/journals\/_\/522\/files\/018-021-wint-42.pdfAccessed: October 2017."},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X10362604"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.1998.1394"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61249-0"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2015.07.009"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000000838"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.593442"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2014.04.019"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph110807961"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.3233\/CH-141907"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2009.10.120"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2015.08.002"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2010.03208.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.12.034"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2007.10.052"},{"key":"e_1_2_8_19_1","unstructured":"NICE guidelines.Peripheral arterial disease: diagnosis and management.London.2012https:\/\/www.nice.org.uk\/guidance\/cg147\/ifp\/chapter\/treating-intermittent-claudication. 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