{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T22:39:45Z","timestamp":1772491185195,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T00:00:00Z","timestamp":1621900800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Physio Funct Imaging"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The forced oscillation technique (FOT) provides detailed information about the mechanics of the respiratory system, while requiring minimal co\u2010operation by the patient. FOT may be abnormal in subjects with normal spirometry and appears to be more closely related to airway symptoms. It is, therefore, attractive in epidemiological studies, where a large number of different examinations are made in each subjects in a short period of time. Current technical standards recommend the mean of three consecutive measurements to be used, but there is limited information regarding within\u2010session variability of FOT measurements.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The purpose of this study was to examine the within\u2010session variability in FOT measurements in a large, population\u2010based sample.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed three consecutive FOT measurements in 700 subjects using the impulse oscillometry system. The first measurement was compared to the mean of three measurements for resistance at 5 and 20\u00a0Hz (R5 and R20, respectively), R5\u2010R20, reactance at 5\u00a0Hz (X5) and resonant frequency (f<jats:sub>res<\/jats:sub>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The differences between the first and the mean of three measurements (median, interquartile range) were minimal, for example 0.002, \u22120.008 to 0.014\u00a0kPa L<jats:sup>\u22121<\/jats:sup>\u00a0s for R5 and \u22120.001, \u22120.008 to 0.005\u00a0kPa L<jats:sup>\u22121<\/jats:sup>\u00a0s for X5. Findings were numerically similar for men and women as well as for subjects with and without airflow obstruction at spirometry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We conclude that, whereas in clinical situations, three FOT measurements are to be preferred, a single measurement may suffice in epidemiological studies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cpf.12706","type":"journal-article","created":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T14:44:07Z","timestamp":1619707447000},"page":"401-407","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Within\u2010session reproducibility of forced oscillometry"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2448-9931","authenticated-orcid":false,"given":"Per","family":"Wollmer","sequence":"first","affiliation":[{"name":"Clinical Physiology and Nuclear Medicine Unit Department of Translational Medicine Lund University Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ellen","family":"Tufvesson","sequence":"additional","affiliation":[{"name":"Respiratory Medicine and Allergology Department of Clinical Sciences Lund Lund University Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9","family":"Wennersten","sequence":"additional","affiliation":[{"name":"Family Medicine and Community Medicine Department of Clinical Sciences Malm\u00f6 Lund University Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulf","family":"Malmqvist","sequence":"additional","affiliation":[{"name":"Division of Clinical Chemistry and Pharmacology Department of Laboratory Medicine Lund University Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunnar","family":"Engstr\u00f6m","sequence":"additional","affiliation":[{"name":"Cardiovascular Research \u2013 Epidemiology Department 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Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulf","family":"Nihl\u00e9n","sequence":"additional","affiliation":[{"name":"Respiratory Medicine and Allergology Department of Clinical Sciences Lund Lund University Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,5,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)90837-8"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2019.06.035"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00160-2019"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1956.8.6.587"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2012.04.010"},{"issue":"1","key":"e_1_2_7_7_1","first-page":"56","article-title":"Variability of forced oscillation (Siemens Siregnost FD 5) measurements of total respiratory resistance in 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