{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T08:00:21Z","timestamp":1774598421475,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:00:00Z","timestamp":1771459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:00:00Z","timestamp":1771459200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Physio Funct Imaging"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Reliable tools for objective response assessment are essential in pleural mesothelioma treated with immunotherapy. We report on a 75\u2010year\u2010old man with sarcomatoid pleural mesothelioma who received a reduced nivolumab dose after developing a hypersensitivity reaction during the first infusion. CT, [\n                    <jats:sup>18<\/jats:sup>\n                    F]FDG PET\/CT and [\n                    <jats:sup>68<\/jats:sup>\n                    Ga]Ga\u2010Fibroblast activation protein inhibitor\u201046 (FAPI) PET\/CT were performed before and after treatment. Despite the reduced dose, the patient experienced clear clinical benefit, and follow\u2010up imaging demonstrated substantial morphological and metabolic improvement across all imaging modalities. This case offers an unique opportunity to directly compare response assessment across three complimentary imaging modalities.\n                  <\/jats:p>","DOI":"10.1111\/cpf.70053","type":"journal-article","created":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T07:24:58Z","timestamp":1771572298000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["FDG and FAPI PET\u2013based response evaluation to reduced\u2010dose nivolumab in pleural mesothelioma: A case report"],"prefix":"10.1111","volume":"46","author":[{"given":"Morten","family":"Bentestuen","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine and Clinical Cancer Research Centre Aalborg University Hospital Aalborg Denmark"},{"name":"Department of Clinical Medicine Aalborg University Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne H.","family":"Thostrup","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine and Clinical Cancer Research Centre Aalborg University Hospital Aalborg Denmark"},{"name":"Department of Clinical Medicine Aalborg University Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weronika M.","family":"Szejniuk","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine Aalborg University Aalborg Denmark"},{"name":"Department of Oncology and Clinical Cancer Research Centre Aalborg University Hospital Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zsuzsanna","family":"Takacs\u2010Szabo","sequence":"additional","affiliation":[{"name":"Department of Radiology Aalborg University Hospital Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thor L.","family":"Rasmussen","sequence":"additional","affiliation":[{"name":"Department of Respiratory Disease Aalborg University Hospital Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9089-288X","authenticated-orcid":false,"given":"Helle D.","family":"Zacho","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine and Clinical Cancer Research Centre Aalborg University Hospital Aalborg Denmark"},{"name":"Department of Clinical Medicine Aalborg University Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,19]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)32714-8"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13164194"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/oemed-2018-105392"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MNM.0000000000001702"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.75.1644"},{"key":"e_1_2_6_7_1","unstructured":"IASLC. (2024) \u2018International Association for the Study of Lung Cancer Staging Cards 9th Edition\u2019.https:\/\/www.iaslc.org\/research-education\/publications-resources-guidelines\/staging-cards-thoracic-oncology-9th-edition"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.124.267473"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.28594"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(24)00119-X"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2021.11.005"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1703481"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semnuclmed.2022.04.008"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.2340\/1651-226X.2024.34802"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-024-06853-0"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-022-05842-5"}],"container-title":["Clinical Physiology and Functional Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cpf.70053","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cpf.70053","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cpf.70053","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T07:31:27Z","timestamp":1774596687000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cpf.70053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,19]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1111\/cpf.70053"],"URL":"https:\/\/doi.org\/10.1111\/cpf.70053","archive":["Portico"],"relation":{},"ISSN":["1475-0961","1475-097X"],"issn-type":[{"value":"1475-0961","type":"print"},{"value":"1475-097X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,19]]},"assertion":[{"value":"2026-01-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70053"}}