{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T09:08:42Z","timestamp":1779872922973,"version":"3.53.1"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T00:00:00Z","timestamp":1777161600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T00:00:00Z","timestamp":1777161600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82170354"],"award-info":[{"award-number":["82170354"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Physio Funct Imaging"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The primary objective of this study was to examine the association between the skeletal muscle mass\u2010to\u2010visceral fat area ratio (SVR) and cardiovascular disease (CVD) prevalence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study employed data from the 2011\u20132018 National Health and Nutrition Examination Survey (NHANES) to derive the SVR using dual\u2010energy X\u2010ray absorptiometry (DXA) measurements. CVD status was ascertained using self\u2010reported physician\u2010diagnosed medical history. Subsequent multivariable logistic regression analyses were performed to examine the relationship between SVR and CVD prevalence. Restricted cubic spline regression was utilized to examine underlying non\u2010linear associations between the SVR and CVD risk. Stratified subgroup analyses were ultimately performed to assess the robustness of the findings. Sensitivity analyses were conducted with additional adjustment for total body fat percentage, and sex\u2010stratified restricted cubic spline analyses were also conducted to explore potential differences in nonlinear associations between men and women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      This study included 9383 participants, among whom 348 were diagnosed with CVD. Multivariable logistic regression models demonstrated a statistically significant inverse relationship between SVR and CVD prevalence (OR\u2009=\u20090.093; 95% CI: 0.016\u20130.542;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.011). The association persisted after adjustment for total body fat percentage. RCS analysis revealed a non\u2010linear association between the SVR and CVD risk. Moreover, subgroup analyses confirmed that the protective effect of SVR remained consistent across various baseline characteristics.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The findings indicate that lower SVR correlates with an elevated risk of CVD, and this association has been robustly demonstrated across multiple studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cpf.70065","type":"journal-article","created":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T05:13:22Z","timestamp":1777266802000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association between appendicular skeletal muscle mass\u2010to\u2010visceral fat area ratio and cardiovascular disease: A cross\u2010sectional study"],"prefix":"10.1111","volume":"46","author":[{"given":"Zehao","family":"Feng","sequence":"first","affiliation":[{"name":"Department of Cardiology &amp; Hongqiao International Institute of Medicine Tongren Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhoufeng","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Oncology Tongren Hospital, Shanghai Jiao Tong University School of Medicine Shanghai City China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaixuan","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Cardiology &amp; Hongqiao International Institute of Medicine Tongren Hospital, Shanghai Jiao Tong University School of Medicine Shanghai 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