{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T09:08:35Z","timestamp":1779872915314,"version":"3.53.1"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T00:00:00Z","timestamp":1779062400000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Physio Funct Imaging"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Exercise transcutaneous oximetry (Ex\u2010TcPO\n                      <jats:sub>2<\/jats:sub>\n                      ), through the minimal value of the \u201cdecrease from rest of oxygen pressure\u201d (DROPmin), identifies ischemia during exercise in patients with PAD. However, its diagnostic performance at the thigh level compared to imaging modalities, has not been evaluated. The objective of this retrospective study was to perform an external validation of Ex\u2010TcPO\u2082 results at the buttock and calf, a first validation of Ex\u2010TcPO\u2082 at the thigh level and to determine the respective diagnostic performance of the DROPmin and DROPend (the DROP at the time of exercise cessation).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We studied 192 patients complaining of intermittent claudication. We retrieved DROPmin and DROPend values from Ex\u2010TcPO\n                      <jats:sub>2<\/jats:sub>\n                      testing and the presence\/absence of an ipsilateral significant stenosis (\u2009\u2265\u200970%) at imaging.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The performance of Ex\u2010TcPO\u2082 using DROPmin values at the buttock, thigh and calf levels were respectively fair (AUC\u2009=\u20090.70; 95% CI: 0.64\u20130.76), fair (AUC\u2009=\u20090.77; 95% CI: 0.72\u20130.83) and excellent (AUC\u2009=\u20090.93; 95% CI: 0.90\u20130.96). When using DROPend, the performance of Ex\u2010TcPO\n                      <jats:sub>2<\/jats:sub>\n                      was no more significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion\/Conclusion<\/jats:title>\n                    <jats:p>This study showed that Ex\u2010TcPO\u2082 has a fair to excellent accuracy for detecting the presence of at least one artery stenosis \u226570% in the lower limb according to buttock, thigh and calf area in highly selected patients. This study also highlights the importance of using the minimal value of DROPmin rather than the DROPend.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cpf.70068","type":"journal-article","created":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T06:25:26Z","timestamp":1779171926000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Performance of exercise transcutaneous oximetry versus imaging at the buttock, thigh and calf level for the diagnosis of peripheral artery disease"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1834-1204","authenticated-orcid":false,"given":"Mari\u00e8ve","family":"Houle","sequence":"first","affiliation":[{"name":"Universit\u00e9 d\u2032Angers, Inserm, CNRS, MITOVASC, Equipe CarMe, SFR ICAT Angers France"},{"name":"Service of Sports Medicine Angers University Hospital Angers 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University Hospital Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7053-2801","authenticated-orcid":false,"given":"Pierre","family":"Abraham","sequence":"additional","affiliation":[{"name":"Universit\u00e9 d\u2032Angers, Inserm, CNRS, MITOVASC, Equipe CarMe, SFR ICAT Angers France"},{"name":"Service of Sports Medicine Angers University Hospital Angers France"},{"name":"Service of Vascular Medicine Angers University Hospital Angers 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European Society for Vascular Surgery (ESVS) 2024 Clinical Practice Guidelines on the Management of Asymptomatic Lower Limb Peripheral Arterial Disease and Intermittent Claudication 5."},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2006.12.037"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2004.52208.x"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2010.09.020"},{"issue":"6","key":"e_1_2_10_32_1","first-page":"645","article-title":"The diagnosis of ischaemic heart pain and intermittent claudication in field surveys","volume":"27","author":"Rose G.A.","year":"1962","journal-title":"Bulletin of the World Health Organization"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(19)30255-4"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-020-01597-6"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2017.00307"}],"container-title":["Clinical Physiology and Functional Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cpf.70068","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cpf.70068","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cpf.70068","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T08:49:21Z","timestamp":1779871761000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cpf.70068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":34,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1111\/cpf.70068"],"URL":"https:\/\/doi.org\/10.1111\/cpf.70068","archive":["Portico"],"relation":{},"ISSN":["1475-0961","1475-097X"],"issn-type":[{"value":"1475-0961","type":"print"},{"value":"1475-097X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"2025-08-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70068"}}