{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T09:46:13Z","timestamp":1792057573412,"version":"4.4.0"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003793","name":"Hj\u00e4rt-Lungfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007436","name":"Familjen Erling-Perssons Stiftelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007436","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004817","name":"Lund University Medical Faculty Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004817","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Physio Funct Imaging"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Surgical mitral valve repair, including anchoring in different parts of the mitral apparatus, is the standard of care for severe mitral regurgitation. Various percutaneous approaches have been developed and are currently under development, but are struggling with durable results. This study investigates the durability of different anatomic anchoring points and anchoring types in the left ventricle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>Anchoring was tested with PTFE sutures or a 5\u2009mm helix at three locations: the head of the papillary muscle, the lateral wall of the ventricle, and the apex of the ventricle. An accelerated life test was performed with 300 cycles at 3\u2009N for each anchoring. Durability was assessed by measuring compliance (strain in mm until 3\u2009N is reached), migration (change in strain from the first to the last cycle), and the occurrence of dehiscence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The lowest numerical strain\/compliance in the first cycle was observed at the head of the papillary muscle anchoring (both surgical and helix). Migration of strain limits over 300 cycles was seen for all locations. The lowest migration was numerically for helix in the papillary muscle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PTFE in the head of the papillary muscle is standard practice in mitral valve repair and was used as a reference in the present study. The anchoring that yielded the most similar results was a helix in the papillary muscle, whereas other anchoring points showed greater compliance and\/or migration.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cpf.70099","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T08:59:41Z","timestamp":1792054781000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The durability of different anchoring points and anchoring types in the left ventricle in an ex vivo porcine model"],"prefix":"10.1111","volume":"46","author":[{"given":"Henrik","family":"Bjursten","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery Lund University, Sk\u00e5ne University Hospital Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Wierup","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sasha","family":"Koul","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Lund Cardiology, Lund University, Sk\u00e5ne University Hospital Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"G\u00f6tberg","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Lund Cardiology, Lund University, Sk\u00e5ne University Hospital Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9991-3712","authenticated-orcid":false,"given":"Magnus","family":"Dencker","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging and Physiology Sk\u00e5ne University Hospital Malm\u00f6 Sweden"},{"name":"Department of Translational Medicine Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,15]]},"reference":[{"issue":"25","key":"e_1_2_10_2_1","doi-asserted-by":"crossref","first-page":"3145","DOI":"10.1161\/01.CIR.0000134276.06719.F3","article-title":"Papillary muscles do not attach directly to the solid heart wall","volume":"109","author":"Axel L.","year":"2004","journal-title":"Circulation"},{"key":"e_1_2_10_3_1","unstructured":"Bjursten H. Kovac T. G\u00f6tberg M.&Dencker M.(2019) Negative pressure\u2010based gripping system and method. US2021 15.08.2019."},{"issue":"2","key":"e_1_2_10_4_1","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.athoracsur.2011.09.015","article-title":"Mitral valve repair with artificial chordae: a review of its history, technical details, long\u2010term results, and pathology","volume":"93","author":"Bortolotti U.","year":"2012","journal-title":"The Annals of Thoracic Surgery"},{"issue":"3","key":"e_1_2_10_5_1","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S0022-5223(19)39144-5","article-title":"Cardiac valve surgery\u2010\u2010the \u201cFrench correction\u201d","volume":"86","author":"Carpentier A.","year":"1983","journal-title":"The Journal of Thoracic and Cardiovascular Surgery"},{"issue":"8","key":"e_1_2_10_6_1","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/j.jacc.2019.06.052","article-title":"Long\u2010Term results of mitral valve repair for regurgitation due to leaflet prolapse","volume":"74","author":"David 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