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Currently, there are still no effective treatments to repair nerve lesions that do not have side effects. Stem cell\u2013based therapies, especially those using dental stem cells, bring new hope to neural diseases. Dental stem cells, derived from the neural crest, have many characteristics that are similar to neural cells, indicating that they can be an ideal source of cells for neural regeneration and repair. This review summarizes the neural traits of all the dental cell types, including DPSCs, PDLCs, DFCs, APSCs and their potential applications in nervous system diseases. We have summed up the advantages of dental stem cells in neural repair, such as their neurotrophic and neuroprotective traits, easy harvest and low rejective reaction rate, among others. Taken together, dental stem cells are an ideal cell source for neural tissue regeneration and repair.<\/jats:p>","DOI":"10.1111\/cpr.12572","type":"journal-article","created":{"date-parts":[[2019,2,4]],"date-time":"2019-02-04T07:29:54Z","timestamp":1549265394000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":58,"title":["Advances of tooth\u2010derived stem cells in neural diseases treatments and nerve tissue regeneration"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8128-7637","authenticated-orcid":false,"given":"Dianri","family":"Wang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Oral Disease, West China Hospital of Stomatology Sichuan University Chengdu China"},{"name":"Department of Oral and Maxillofacial Surgery, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology Sichuan University Chengdu China"},{"name":"National 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