{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T22:25:34Z","timestamp":1793744734711,"version":"4.6.1"},"reference-count":162,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T00:00:00Z","timestamp":1704844800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82030067"],"award-info":[{"award-number":["82030067"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82161160342"],"award-info":[{"award-number":["82161160342"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82172397"],"award-info":[{"award-number":["82172397"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82250710174"],"award-info":[{"award-number":["82250710174"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cell Proliferation"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Osteoarthritis (OA) is the most prevalent disorder of synovial joint affecting multiple joints. In the past decade, we have witnessed conceptual switch of OA pathogenesis from a \u2018wear and tear\u2019 disease to a disease affecting entire joint. Extensive studies have been conducted to understand the underlying mechanisms of OA using genetic mouse models and ex vivo joint tissues derived from individuals with OA. These studies revealed that multiple signalling pathways are involved in OA development, including the canonical Wnt\/\u03b2\u2010catenin signalling and its interaction with other signalling pathways, such as transforming growth factor \u03b2 (TGF\u2010\u03b2), bone morphogenic protein (BMP), Indian Hedgehog (Ihh), nuclear factor \u03baB (NF\u2010\u03baB), fibroblast growth factor (FGF), and Notch. The identification of signalling interaction and underlying mechanisms are currently underway and the specific molecule(s) and key signalling pathway(s) playing a decisive role in OA development need to be evaluated. This review will focus on recent progresses in understanding of the critical role of Wnt\/\u03b2\u2010catenin signalling in OA pathogenesis and interaction of \u03b2\u2010catenin with other pathways, such as TGF\u2010\u03b2, BMP, Notch, Ihh, NF\u2010\u03baB, and FGF. Understanding of these novel insights into the interaction of \u03b2\u2010catenin with other pathways and its integration into a complex gene regulatory network during OA development will help us identify the key signalling pathway of OA pathogenesis leading to the discovery of novel therapeutic strategies for OA intervention.<\/jats:p>","DOI":"10.1111\/cpr.13600","type":"journal-article","created":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T01:09:22Z","timestamp":1704935362000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Signalling interaction between \u03b2\u2010catenin and other signalling molecules during osteoarthritis development"],"prefix":"10.1111","volume":"57","author":[{"given":"Jing","family":"Feng","sequence":"first","affiliation":[{"name":"Department of Orthopedics, Traditional Chinese and Western Medicine Hospital of Wuhan Tongji Medical College, Huazhong University of Science and Technology  Wuhan Hubei China"},{"name":"Department of Orthopedics Wuhan No. 1 Hospital  Wuhan Hubei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Emergency Renmin Hospital, Wuhan University  Wuhan Hubei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feifei","family":"Pu","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Traditional Chinese and Western Medicine Hospital of Wuhan Tongji Medical College, Huazhong University of Science and Technology  Wuhan Hubei China"},{"name":"Department of Orthopedics Wuhan No. 1 Hospital  Wuhan Hubei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9943-8576","authenticated-orcid":false,"given":"Zhenglin","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery the First Affiliated Hospital of Chongqing Medical University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Lu","sequence":"additional","affiliation":[{"name":"Faculty of Pharmaceutical Sciences Shenzhen Institute of Advanced Technology  Shenzhen China"},{"name":"Research Center for Computer\u2010aided Drug Discovery Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William W.","family":"Lu","sequence":"additional","affiliation":[{"name":"Faculty of Pharmaceutical Sciences Shenzhen Institute of Advanced Technology  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Tong","sequence":"additional","affiliation":[{"name":"Research Center for Computer\u2010aided Drug Discovery Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1913-5760","authenticated-orcid":false,"given":"Huan","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Traditional Chinese and Western Medicine Hospital of Wuhan Tongji Medical College, Huazhong University of Science and Technology  Wuhan Hubei China"},{"name":"Department of Orthopedics Wuhan No. 1 Hospital  Wuhan Hubei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4258-3457","authenticated-orcid":false,"given":"Di","family":"Chen","sequence":"additional","affiliation":[{"name":"Faculty of Pharmaceutical Sciences Shenzhen Institute of Advanced Technology  Shenzhen China"},{"name":"Research Center for Computer\u2010aided Drug Discovery Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,10]]},"reference":[{"key":"e_1_2_17_2_1","first-page":"9","article-title":"Osteoarthritis pain","volume":"23","author":"Yu H","year":"2022","journal-title":"Int J Mol Sci"},{"key":"e_1_2_17_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41413-022-00226-9"},{"key":"e_1_2_17_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2019-216515"},{"key":"e_1_2_17_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.42089"},{"key":"e_1_2_17_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-021-01905-w"},{"key":"e_1_2_17_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01330-w"},{"key":"e_1_2_17_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph16234701"},{"key":"e_1_2_17_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2022.12.056"},{"key":"e_1_2_17_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2023.03.010"},{"key":"e_1_2_17_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/boneres.2016.44"},{"key":"e_1_2_17_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jot.2022.09.003"},{"key":"e_1_2_17_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jot.2022.11.007"},{"key":"e_1_2_17_14_1","doi-asserted-by":"publisher","DOI":"10.5435\/JAAOS-D-21-01233"},{"key":"e_1_2_17_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/08977194.2018.1548444"},{"key":"e_1_2_17_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jot.2019.11.008"},{"key":"e_1_2_17_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jot.2022.02.009"},{"key":"e_1_2_17_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/cpr.13517"},{"key":"e_1_2_17_19_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2218238120"},{"key":"e_1_2_17_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-017-0679-z"},{"key":"e_1_2_17_21_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.22.01092"},{"key":"e_1_2_17_22_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2217096120"},{"key":"e_1_2_17_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/bies.10136"},{"key":"e_1_2_17_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.3700747"},{"key":"e_1_2_17_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jot.2022.10.005"},{"key":"e_1_2_17_26_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M414275200"},{"key":"e_1_2_17_27_1","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.080901"},{"key":"e_1_2_17_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.28491"},{"key":"e_1_2_17_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41368-018-0016-z"},{"key":"e_1_2_17_30_1","doi-asserted-by":"publisher","DOI":"10.22203\/eCM.v028a15"},{"key":"e_1_2_17_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.23614"},{"key":"e_1_2_17_32_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.23000"},{"key":"e_1_2_17_33_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2018-214200"},{"key":"e_1_2_17_34_1","doi-asserted-by":"publisher","DOI":"10.1080\/21691401.2019.1593853"},{"key":"e_1_2_17_35_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-019-2041-5"},{"key":"e_1_2_17_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-022-02848-0"},{"key":"e_1_2_17_37_1","doi-asserted-by":"publisher","DOI":"10.1177\/03635465231164644"},{"key":"e_1_2_17_38_1","doi-asserted-by":"publisher","DOI":"10.18632\/aging.203707"},{"key":"e_1_2_17_39_1","article-title":"Wnt10b regulates osteogenesis of adipose\u2010derived stem cells through Wnt\/beta\u2010catenin signalling pathway in osteoporosis","author":"Huang K","year":"2023","journal-title":"Cell Prolif"},{"key":"e_1_2_17_40_1","doi-asserted-by":"publisher","DOI":"10.1086\/338450"},{"key":"e_1_2_17_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(01)00571-2"},{"key":"e_1_2_17_42_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa013444"},{"key":"e_1_2_17_43_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.3437105"},{"key":"e_1_2_17_44_1","doi-asserted-by":"publisher","DOI":"10.1086\/318811"},{"key":"e_1_2_17_45_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.39.2.91"},{"key":"e_1_2_17_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60599-1"},{"key":"e_1_2_17_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-013-2302-0"},{"key":"e_1_2_17_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2249"},{"key":"e_1_2_17_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.38799"},{"key":"e_1_2_17_50_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2023.1057154"},{"key":"e_1_2_17_51_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.607764"},{"key":"e_1_2_17_52_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-021-04886-2"},{"key":"e_1_2_17_53_1","doi-asserted-by":"publisher","DOI":"10.1177\/1759720X12437353"},{"key":"e_1_2_17_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jot.2022.10.015"},{"key":"e_1_2_17_55_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2007.075572"},{"key":"e_1_2_17_56_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2011-200970"},{"key":"e_1_2_17_57_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2012-202231"},{"key":"e_1_2_17_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/jre.13023"},{"key":"e_1_2_17_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2015.03.013"},{"key":"e_1_2_17_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.40206"},{"key":"e_1_2_17_61_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.96308"},{"key":"e_1_2_17_62_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard-2022-222773"},{"key":"e_1_2_17_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jot.2021.08.002"},{"key":"e_1_2_17_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jot.2021.06.004"},{"key":"e_1_2_17_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/boneres.2014.2"},{"key":"e_1_2_17_66_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.23946"},{"key":"e_1_2_17_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1063-4584(03)00165-1"},{"key":"e_1_2_17_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/cpr.12904"},{"key":"e_1_2_17_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/cpr.13489"},{"key":"e_1_2_17_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.38122"},{"key":"e_1_2_17_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2007.08.001"},{"key":"e_1_2_17_72_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar4133"},{"key":"e_1_2_17_73_1","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1402.082"},{"key":"e_1_2_17_74_1","doi-asserted-by":"publisher","DOI":"10.1359\/JBMR.0301239"},{"key":"e_1_2_17_75_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-31697-3"},{"key":"e_1_2_17_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2014.01.021"},{"key":"e_1_2_17_77_1","doi-asserted-by":"publisher","DOI":"10.1111\/cpr.12998"},{"key":"e_1_2_17_78_1","doi-asserted-by":"publisher","DOI":"10.1111\/cpr.13310"},{"key":"e_1_2_17_79_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.869422"},{"key":"e_1_2_17_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ocarto.2022.100240"},{"key":"e_1_2_17_81_1","doi-asserted-by":"publisher","DOI":"10.1006\/excr.1994.1033"},{"key":"e_1_2_17_82_1","doi-asserted-by":"publisher","DOI":"10.1080\/08977190802291733"},{"key":"e_1_2_17_83_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23042084"},{"key":"e_1_2_17_84_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.11248"},{"key":"e_1_2_17_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-4889(99)00100-7"},{"key":"e_1_2_17_86_1","doi-asserted-by":"publisher","DOI":"10.1080\/0897719031000148822"},{"key":"e_1_2_17_87_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.20359"},{"key":"e_1_2_17_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2015.02.007"},{"key":"e_1_2_17_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.07.038"},{"key":"e_1_2_17_90_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23094672"},{"key":"e_1_2_17_91_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0127166"},{"key":"e_1_2_17_92_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2016.199"},{"key":"e_1_2_17_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2014.02.004"},{"key":"e_1_2_17_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2012.09.029"},{"key":"e_1_2_17_95_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.22319"},{"key":"e_1_2_17_96_1","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2003.18.10.1842"},{"key":"e_1_2_17_97_1","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.090806"},{"key":"e_1_2_17_98_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.132233"},{"key":"e_1_2_17_99_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar3805"},{"key":"e_1_2_17_100_1","doi-asserted-by":"publisher","DOI":"10.1111\/febs.16815"},{"key":"e_1_2_17_101_1","doi-asserted-by":"publisher","DOI":"10.1111\/cpr.13156"},{"key":"e_1_2_17_102_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.201138"},{"key":"e_1_2_17_103_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-022-01031-6"},{"key":"e_1_2_17_104_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1207458110"},{"key":"e_1_2_17_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2015.10.015"},{"key":"e_1_2_17_106_1","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.aaa3792"},{"key":"e_1_2_17_107_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-014-2163-7"},{"key":"e_1_2_17_108_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-015-0103-4"},{"key":"e_1_2_17_109_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2016.5324"},{"key":"e_1_2_17_110_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.3530"},{"key":"e_1_2_17_111_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M508370200"},{"key":"e_1_2_17_112_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2003-0463"},{"key":"e_1_2_17_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2018.01.010"},{"key":"e_1_2_17_114_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbf.3448"},{"key":"e_1_2_17_115_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI80205"},{"key":"e_1_2_17_116_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2055"},{"key":"e_1_2_17_117_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.41250"},{"key":"e_1_2_17_118_1","doi-asserted-by":"publisher","DOI":"10.1111\/febs.16440"},{"key":"e_1_2_17_119_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar4437"},{"key":"e_1_2_17_120_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-018-0327-1"},{"key":"e_1_2_17_121_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.018044"},{"key":"e_1_2_17_122_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.50208"},{"key":"e_1_2_17_123_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.02546"},{"key":"e_1_2_17_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jot.2023.03.002"},{"key":"e_1_2_17_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2020.113447"},{"key":"e_1_2_17_126_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M104227200"},{"key":"e_1_2_17_127_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2006.02.014"},{"key":"e_1_2_17_128_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.02-06-0101"},{"key":"e_1_2_17_129_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2005.03.006"},{"key":"e_1_2_17_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2010.01.006"},{"key":"e_1_2_17_131_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M506206200"},{"key":"e_1_2_17_132_1","doi-asserted-by":"publisher","DOI":"10.1158\/1541-7786.MCR-10-0248"},{"key":"e_1_2_17_133_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.34425"},{"key":"e_1_2_17_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2023.116817"},{"key":"e_1_2_17_135_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2018-00184"},{"key":"e_1_2_17_136_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.17174"},{"key":"e_1_2_17_137_1","doi-asserted-by":"publisher","DOI":"10.4103\/CJP.CJP_11_19"},{"key":"e_1_2_17_138_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2009.00678.x"},{"key":"e_1_2_17_139_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2016.06.003"},{"key":"e_1_2_17_140_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0174969"},{"key":"e_1_2_17_141_1","doi-asserted-by":"publisher","DOI":"10.1210\/me.2009-0085"},{"key":"e_1_2_17_142_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M611129200"},{"key":"e_1_2_17_143_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2014.12.020"},{"key":"e_1_2_17_144_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.27043"},{"key":"e_1_2_17_145_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00418-018-1640-6"},{"key":"e_1_2_17_146_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10495-022-01787-0"},{"key":"e_1_2_17_147_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.22041"},{"key":"e_1_2_17_148_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-02490-w"},{"key":"e_1_2_17_149_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.3737"},{"issue":"2","key":"e_1_2_17_150_1","first-page":"168","article-title":"Molecular mechanism of Runx2\u2010dependent bone development","volume":"43","author":"Komori T","year":"2020","journal-title":"Mol Cells"},{"key":"e_1_2_17_151_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20071694"},{"key":"e_1_2_17_152_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M305472200"},{"key":"e_1_2_17_153_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.teb.2012.0527"},{"key":"e_1_2_17_154_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2016.06.007"},{"key":"e_1_2_17_155_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-25395-8"},{"key":"e_1_2_17_156_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2009.05212.x"},{"key":"e_1_2_17_157_1","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.071115"},{"key":"e_1_2_17_158_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41413-023-00253-0"},{"key":"e_1_2_17_159_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41413-018-0017-8"},{"key":"e_1_2_17_160_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-17-2157"},{"key":"e_1_2_17_161_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.1700090"},{"key":"e_1_2_17_162_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.13864"},{"key":"e_1_2_17_163_1","doi-asserted-by":"publisher","DOI":"10.1038\/s12276-020-0380-6"}],"container-title":["Cell Proliferation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cpr.13600","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T03:51:03Z","timestamp":1717559463000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cpr.13600"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,10]]},"references-count":162,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1111\/cpr.13600"],"URL":"https:\/\/doi.org\/10.1111\/cpr.13600","archive":["Portico"],"relation":{},"ISSN":["0960-7722","1365-2184"],"issn-type":[{"value":"0960-7722","type":"print"},{"value":"1365-2184","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,10]]},"assertion":[{"value":"2023-09-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13600"}}