{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:43:31Z","timestamp":1792716211098,"version":"4.5.0"},"reference-count":157,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T00:00:00Z","timestamp":1733184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2020MC083"],"award-info":[{"award-number":["ZR2020MC083"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2021MH350"],"award-info":[{"award-number":["ZR2021MH350"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32070859"],"award-info":[{"award-number":["32070859"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008118","name":"Shandong Academy of Sciences","doi-asserted-by":"publisher","award":["2022JBZ02\u221206"],"award-info":[{"award-number":["2022JBZ02\u221206"]}],"id":[{"id":"10.13039\/501100008118","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008118","name":"Shandong Academy of Sciences","doi-asserted-by":"publisher","award":["2024ZDZX14"],"award-info":[{"award-number":["2024ZDZX14"]}],"id":[{"id":"10.13039\/501100008118","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cell Proliferation"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Osteoarthritis (OA) is a chronic, degenerative joint disease primarily characterised by damage to the articular cartilage, synovitis and persistent pain, and has become one of the most common diseases worldwide. In OA cartilage, various forms of cell death have been identified, including apoptosis, necroptosis and autophagic cell death. Ever\u2010growing observations indicate that ferroptosis, a newly\u2010discovered iron\u2010dependent form of regulated cell death, is detrimental to OA occurrence and progression. In this review, we first analyse the pathogenetic mechanisms of OA by which iron overload, inflammatory response and mechanical stress contribute to ferroptosis. We then discuss how ferroptosis exacerbates OA progression, focusing on its impact on chondrocyte viability, synoviocyte populations and extracellular matrix integrity. Finally, we highlight several potential therapeutic strategies targeting ferroptosis that could be explored for the treatment of OA.<\/jats:p>","DOI":"10.1111\/cpr.13779","type":"journal-article","created":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T05:40:46Z","timestamp":1733204446000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Ferroptosis in Osteoarthritis: Towards Novel Therapeutic Strategy"],"prefix":"10.1111","volume":"58","author":[{"given":"Yiming","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Genetics and Cell Biology, School of Basic Medicine Qingdao University  Qingdao China"},{"name":"Department of Reproductive Medicine The\u00a0Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Hematology Rizhao People's Hospital  Rizhao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiane","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Genetics and Cell Biology, School of Basic Medicine Qingdao University  Qingdao China"},{"name":"Department of Reproductive Medicine The\u00a0Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of\u00a0Hematology The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kehan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Genetics and Cell Biology, School of Basic Medicine Qingdao University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Genetics and Cell Biology, School of Basic Medicine Qingdao University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufeng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Genetics and Cell Biology, School of Basic Medicine Qingdao University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daijie","family":"Wang","sequence":"additional","affiliation":[{"name":"International Joint Laboratory of Medicinal Food R&amp;D and Health Products Creation\/Biological Engineering Technology Innovation Center of Shandong Province Heze Branch of Qilu University of Technology (Shandong Academy of Sciences)  Heze China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6215-9127","authenticated-orcid":false,"given":"Xiao","family":"Hu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Basic and Translational Research on Immune\u2010Mediated Skin Diseases; Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4471-5983","authenticated-orcid":false,"given":"Zheng","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Genetics and Cell Biology, School of Basic Medicine Qingdao University  Qingdao China"},{"name":"Department of Reproductive Medicine The\u00a0Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,12,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)32230-3"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.1980"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu10081030"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsa.2016.05.009"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2021.12.012"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2023.115707"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-023-03476-6"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.03.042"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2019.224899"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.4922793"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.13-240564"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0162-0134(87)85001-8"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2017.07.015"},{"issue":"5","key":"e_1_2_10_15_1","first-page":"1895","article-title":"The Role of Iron Homeostasis and Iron\u2010Mediated ROS in Cancer","volume":"11","author":"Ying J. F.","year":"2021","journal-title":"American Journal of Cancer Research"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/360438"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2023.1112751"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2011.4391"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-21841-w"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1707-0"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2020.10.011"},{"issue":"5","key":"e_1_2_10_22_1","first-page":"591","article-title":"Tetrahydrobioterin (BH4) Pathway: From Metabolism to Neuropsychiatry","volume":"19","author":"Fanet H.","year":"2021","journal-title":"Current Neuropharmacology"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2020.00110"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2024.1290234"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.896494"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.2010.02429.x"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-physiol-022522-102832"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(14)70117-6"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2017.00077"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2021.12.257"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu14081674"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1385\/BTER:106:2:123"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.2174\/1874312901409010065"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41420-023-01613-9"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.39707"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-201303020-00005"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2019.07.018"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jare.2022.01.004"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells11213430"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-20-0617"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.02523"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/561459"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cytogfr.2018.10.002"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.5312\/wjo.v6.i1.95"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S203094"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jot.2020.09.006"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V87.6.2525.bloodjournal8762525"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2023.03.008"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2020.9504"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature13148"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2022.992044"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2022.103847"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.01378"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1177\/19476035221142011"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2024.103255"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2024.103143"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.113517"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-209757"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1705-2"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2022.12.006"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/ddr.21412"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0069362"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm-21-6942"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1168799"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2020.111199"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1111\/cpr.13134"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2153"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2146"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/24.4.488"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2014.06.021"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41422-023-00848-6"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-020-0461-8"},{"key":"e_1_2_10_73_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu10040471"},{"key":"e_1_2_10_74_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24010449"},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2019.101107"},{"key":"e_1_2_10_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2021.02.564"},{"key":"e_1_2_10_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.01.007"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2016.08.011"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12071480"},{"key":"e_1_2_10_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2023.110159"},{"key":"e_1_2_10_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2022.110148"},{"issue":"12","key":"e_1_2_10_82_1","first-page":"5775","article-title":"Astaxanthin Prevents Osteoarthritis by Blocking Rspo2\u2010Mediated Wnt\/\u03b2\u2010Catenin Signaling in Chondrocytes and Abolishing Rspo2\u2010Related Inflammatory Factors in Macrophages","volume":"15","author":"Zhu C.","year":"2023","journal-title":"Aging (Albany NY)"},{"key":"e_1_2_10_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2010.05.012"},{"key":"e_1_2_10_84_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules15117861"},{"key":"e_1_2_10_85_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-019-1472-x"},{"key":"e_1_2_10_86_1","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.issn.0366-6999.20122380"},{"key":"e_1_2_10_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2012.10.004"},{"key":"e_1_2_10_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbb.2015.09.013"},{"key":"e_1_2_10_89_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules21050548"},{"key":"e_1_2_10_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.113915"},{"key":"e_1_2_10_91_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/3531995"},{"key":"e_1_2_10_92_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41418-019-0380-z"},{"key":"e_1_2_10_93_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-59898-0"},{"key":"e_1_2_10_94_1","doi-asserted-by":"publisher","DOI":"10.1089\/jmf.2019.4552"},{"key":"e_1_2_10_95_1","doi-asserted-by":"publisher","DOI":"10.18388\/abp.2012_2088"},{"key":"e_1_2_10_96_1","doi-asserted-by":"publisher","DOI":"10.1080\/21655979.2021.2000742"},{"key":"e_1_2_10_97_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300060513507392"},{"key":"e_1_2_10_98_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0035753"},{"key":"e_1_2_10_99_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-19-1500"},{"key":"e_1_2_10_100_1","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci13010145"},{"key":"e_1_2_10_101_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox10060862"},{"key":"e_1_2_10_102_1","doi-asserted-by":"publisher","DOI":"10.4014\/jmb.2103.03057"},{"key":"e_1_2_10_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2023.113644"},{"key":"e_1_2_10_104_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina57090898"},{"key":"e_1_2_10_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2015.01.041"},{"key":"e_1_2_10_106_1","doi-asserted-by":"publisher","DOI":"10.1002\/dta.2128"},{"key":"e_1_2_10_107_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546517716631"},{"key":"e_1_2_10_108_1","doi-asserted-by":"publisher","DOI":"10.1177\/0963689719861922"},{"key":"e_1_2_10_109_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.22690"},{"key":"e_1_2_10_110_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.918565"},{"key":"e_1_2_10_111_1","doi-asserted-by":"publisher","DOI":"10.1089\/cell.2023.0019"},{"key":"e_1_2_10_112_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2009.104"},{"key":"e_1_2_10_113_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-017-0719-7"},{"key":"e_1_2_10_114_1","doi-asserted-by":"publisher","DOI":"10.1302\/2046-3758.32.2000187"},{"key":"e_1_2_10_115_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2023.110566"},{"key":"e_1_2_10_116_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10863-023-09991-6"},{"key":"e_1_2_10_117_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/9501747"},{"key":"e_1_2_10_118_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-023-08495-1"},{"key":"e_1_2_10_119_1","doi-asserted-by":"publisher","DOI":"10.2174\/0929867326666190503121546"},{"key":"e_1_2_10_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.111228"},{"key":"e_1_2_10_121_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-43308-w"},{"key":"e_1_2_10_122_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2023.12.038"},{"key":"e_1_2_10_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.11.025"},{"key":"e_1_2_10_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2023.105179"},{"key":"e_1_2_10_125_1","doi-asserted-by":"publisher","DOI":"10.2147\/JIR.S403819"},{"key":"e_1_2_10_126_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41418-017-0012-4"},{"key":"e_1_2_10_127_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1063-4584(03)00150-X"},{"key":"e_1_2_10_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2020.110452"},{"key":"e_1_2_10_129_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2022.1001212"},{"key":"e_1_2_10_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2024.116548"},{"key":"e_1_2_10_131_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-023-01369-w"},{"key":"e_1_2_10_132_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1435139"},{"key":"e_1_2_10_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2024.102248"},{"key":"e_1_2_10_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2024.105088"},{"key":"e_1_2_10_135_1","doi-asserted-by":"publisher","DOI":"10.1111\/febs.16059"},{"key":"e_1_2_10_136_1","doi-asserted-by":"publisher","DOI":"10.1097\/CAD.0000000000000825"},{"key":"e_1_2_10_137_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41401-023-01062-1"},{"key":"e_1_2_10_138_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.4c00555"},{"key":"e_1_2_10_139_1","doi-asserted-by":"publisher","DOI":"10.1080\/08923973.2023.2300508"},{"key":"e_1_2_10_140_1","doi-asserted-by":"publisher","DOI":"10.5114\/reum\/172211"},{"key":"e_1_2_10_141_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2023.07.007"},{"key":"e_1_2_10_142_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2009.02186.x"},{"key":"e_1_2_10_143_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.791376"},{"key":"e_1_2_10_144_1","doi-asserted-by":"publisher","DOI":"10.1111\/febs.16772"},{"key":"e_1_2_10_145_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2023.110131"},{"issue":"5","key":"e_1_2_10_146_1","first-page":"543","article-title":"A Randomized Clinical Trial of High\u2010Dosage Coenzyme Q10 in Early Parkinson Disease: No Evidence of Benefit","volume":"71","author":"Beal M. F.","year":"2014","journal-title":"Journal of the American Medical Association Neurology"},{"key":"e_1_2_10_147_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jot.2023.02.005"},{"key":"e_1_2_10_148_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-023-03673-0"},{"key":"e_1_2_10_149_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2022.104258"},{"key":"e_1_2_10_150_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-022-05065-4"},{"key":"e_1_2_10_151_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-022-01547-5"},{"key":"e_1_2_10_152_1","article-title":"miR\u20101 Inhibits the Ferroptosis of Chondrocyte by Targeting CX43 and Alleviates Osteoarthritis Progression","author":"Zhou M.","year":"2023","journal-title":"Journal of Immunology Research"},{"key":"e_1_2_10_153_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199410063311401"},{"key":"e_1_2_10_154_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2017.03.009"},{"key":"e_1_2_10_155_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells11030529"},{"key":"e_1_2_10_156_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-017-0510-9"},{"key":"e_1_2_10_157_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcot.2022.101772"},{"key":"e_1_2_10_158_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2014.09.030"}],"container-title":["Cell Proliferation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cpr.13779","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T11:38:19Z","timestamp":1741693099000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cpr.13779"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,3]]},"references-count":157,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["10.1111\/cpr.13779"],"URL":"https:\/\/doi.org\/10.1111\/cpr.13779","archive":["Portico"],"relation":{},"ISSN":["0960-7722","1365-2184"],"issn-type":[{"value":"0960-7722","type":"print"},{"value":"1365-2184","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,3]]},"assertion":[{"value":"2024-07-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13779"}}