{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T22:00:17Z","timestamp":1759960817026},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,1,10]],"date-time":"2014-01-10T00:00:00Z","timestamp":1389312000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Fifty percent of patients with primary ciliary dyskinesia (<jats:styled-content style=\"fixed-case\">PCD<\/jats:styled-content>) have situs inversus. Diffuse panbronchiolitis (<jats:styled-content style=\"fixed-case\">DPB<\/jats:styled-content>) might be one of the characteristic features of the lung in <jats:styled-content style=\"fixed-case\">PCD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reported a case of <jats:styled-content style=\"fixed-case\">PCD<\/jats:styled-content> without situs inversus, yet complicated with <jats:styled-content style=\"fixed-case\">DPB<\/jats:styled-content>, and did literature review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A 34\u2010year\u2010old nonsmoking <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hinese woman with 6\u2010year primary infertility suffered from recurrent episodes of respiratory tract infections since childhood. Lung auscultation revealed end\u2010inspiratory coarse crackles. Pulmonary function tests demonstrated mild obstructive ventilation functional impairment. Lung biopsy showed respiratory bronchiolitis. Nasal mucosa cilia showed the absence of both outer and inner dynein arms of the microtubules. Saccharin test was positive. Chest images showed bronchiectasis and bronchiolitis but no situs inversus. Paranasal sinus computed tomography (<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>) showed maxillary sinusitis and ethmoid sinusitis. A culture of bronchoalveolar lavage fluid was positive for <jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>seudomonas aeruginosa<\/jats:italic>. Her conditions improved in clinical symptoms and <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> images after 2 months of treatment with azithromycin. Literature review revealed that very rare patients were diagnosed as <jats:styled-content style=\"fixed-case\">PCD<\/jats:styled-content> complicated with diffuse <jats:styled-content style=\"fixed-case\">DPB<\/jats:styled-content>, and all of them had situs inversus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The association of <jats:styled-content style=\"fixed-case\">DPB<\/jats:styled-content> might be one of the characteristic features of the lung in <jats:styled-content style=\"fixed-case\">PCD<\/jats:styled-content>. Further studies on the concurrence of these two diseases are suggested so as to elucidate the mechanism of both.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.12089","type":"journal-article","created":{"date-parts":[[2013,12,6]],"date-time":"2013-12-06T10:47:19Z","timestamp":1386326839000},"page":"425-430","source":"Crossref","is-referenced-by-count":7,"title":["Primary ciliary dyskinesia complicated with diffuse panbronchiolitis: a case report and literature review"],"prefix":"10.1111","volume":"8","author":[{"given":"Wei","family":"Chen","sequence":"first","affiliation":[{"name":"Shanghai Institute of Respiratory Diseases Zhongshan Hospital Shanghai Medical College of Fudan University  Shanghai China"},{"name":"Department of Respiratory Medicine Huai'an First People's Hospital Nanjing Medical University  Huai'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changzhou","family":"Shao","sequence":"additional","affiliation":[{"name":"Shanghai Institute of Respiratory Diseases Zhongshan Hospital Shanghai Medical College of Fudan University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanlin","family":"Song","sequence":"additional","affiliation":[{"name":"Shanghai Institute of Respiratory Diseases Zhongshan Hospital Shanghai Medical College of Fudan University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunxue","family":"Bai","sequence":"additional","affiliation":[{"name":"Shanghai Institute of Respiratory Diseases Zhongshan Hospital Shanghai Medical College of Fudan University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,1,10]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.98.12040982"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/LBR.0b013e318203cc4e"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.06.00131805"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-012-1785-6"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2002.tb03299.x"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-37132007000500017"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2006.096958"},{"key":"e_1_2_4_9_1","first-page":"201","article-title":"Primary ciliary dyskinesia. 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