{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T22:16:04Z","timestamp":1765232164208,"version":"3.37.3"},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,8,4]],"date-time":"2014-08-04T00:00:00Z","timestamp":1407110400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2016,3]]},"abstract":"Abstract<\/jats:title>H<\/jats:italic><\/jats:styled-content>istoplasma capsulatum<\/jats:italic> can rarely affect the trachea. We report the case of a 68\u2010year\u2010old woman with rheumatoid arthritis on immunosuppressive therapy who presented with fevers, worsening shortness of breath, nonproductive cough and subjective throat hoarseness and fullness. Chest computed tomography demonstrated no tracheal findings. Bronchoscopy found mucosal irregularity, nodularity and vesicular regions in the proximal trachea extending seven centimeters distal to the vocal cords. Also seen was an edematous, exudative left vocal cord with polyps and an ulcerative lesion. Silver staining and culture and wash of the tracheal biopsy revealed H<\/jats:italic><\/jats:styled-content>istoplasma capsulatum<\/jats:italic>. She was treated with oral itraconazole then briefly on intravenous amphotericin for rising H<\/jats:italic><\/jats:styled-content>istoplasma<\/jats:italic> urinary antigen levels. She continued treatment 24 months following diagnosis with minimal dyspnea. H<\/jats:italic><\/jats:styled-content>istoplasma<\/jats:italic> tracheitis has been proposed as an indicator of disseminated infection. However, our patient did not demonstrate other organ manifestations. H<\/jats:italic><\/jats:styled-content>istoplasma<\/jats:italic> tracheitis should be considered in a differential diagnosis of tracheal lesions even in the absence of systemic involvement.<\/jats:p>","DOI":"10.1111\/crj.12185","type":"journal-article","created":{"date-parts":[[2014,7,11]],"date-time":"2014-07-11T08:55:42Z","timestamp":1405068942000},"page":"255-258","source":"Crossref","is-referenced-by-count":3,"title":["Nondisseminated histoplasmosis of the trachea"],"prefix":"10.1111","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7998-4131","authenticated-orcid":false,"given":"Nicholas","family":"Bhojwani","sequence":"first","affiliation":[{"name":"Department of Radiology University Hospitals Case Medical Center Cleveland OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason Brett","family":"Hartman","sequence":"additional","affiliation":[{"name":"School of Medicine Case Western Reserve University Cleveland OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David C.","family":"Taylor","sequence":"additional","affiliation":[{"name":"Department of Pathology Mount Carmel Health System Columbus OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Herbert","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease Mount Carmel Health System Columbus OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Corriveau","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Mount Carmel Health System Columbus OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,8,4]]},"reference":[{"key":"e_1_2_2_2_1","first-page":"893","article-title":"Molecular evolution of the fungi: human pathogens","volume":"9","author":"Bowman BH","year":"1992","journal-title":"Mol Biol Evol"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-824898"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-94-3-331"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198001000-00001"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0b013e318144b1d9"},{"key":"e_1_2_2_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197205000-00008"},{"key":"e_1_2_2_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/srin.2001.24242"},{"key":"e_1_2_2_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198107000-00001"},{"key":"e_1_2_2_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2003.12.045"},{"key":"e_1_2_2_11_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.09-0236"}],"container-title":["The Clinical Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcrj.12185","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/crj.12185","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T02:39:34Z","timestamp":1696300774000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/crj.12185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,4]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["10.1111\/crj.12185"],"URL":"https:\/\/doi.org\/10.1111\/crj.12185","archive":["Portico"],"relation":{},"ISSN":["1752-6981","1752-699X"],"issn-type":[{"type":"print","value":"1752-6981"},{"type":"electronic","value":"1752-699X"}],"subject":[],"published":{"date-parts":[[2014,8,4]]}}}