{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T13:55:39Z","timestamp":1760622939913,"version":"3.37.3"},"reference-count":7,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,3,3]],"date-time":"2015-03-03T00:00:00Z","timestamp":1425340800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2016,9]]},"abstract":"Abstract<\/jats:title>Introduction<\/jats:title>There are several papers on the sonographic features of mediastinal lymph nodes affected by several diseases, but none gives the importance and clinical utility of the features.<\/jats:p><\/jats:sec>Objective<\/jats:title>In order to find out which lymph node should be sampled in a particular nodal station during endobronchial ultrasound, we investigated the diagnostic performances of certain sonographic features and proposed an algorithmic approach.<\/jats:p><\/jats:sec>Methods<\/jats:title>We retrospectively analyzed 1051 lymph nodes and randomly assigned them into a preliminary experimental and a secondary study group. The diagnostic performances of the sonographic features (gray scale, echogeneity, shape, size, margin, presence of necrosis, presence of calcification and absence of central hilar structure) were calculated, and an algorithm for lymph node sampling was obtained with decision tree analysis in the experimental group. Later, a modified algorithm was applied to the patients in the study group to give the accuracy.<\/jats:p><\/jats:sec>Results<\/jats:title>The demographic characteristics of the patients were not statistically significant between the primary and the secondary groups. All of the features were discriminative between malignant and benign diseases. The modified algorithm sensitivity, specificity, and positive and negative predictive values and diagnostic accuracy for detecting metastatic lymph nodes were 100%, 51.2%, 50.6%, 100% and 67.5%, respectively.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>In this retrospective analysis, the standardized sonographic classification system and the proposed algorithm performed well in choosing the node that should be sampled in a particular station during endobronchial ultrasound.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.12267","type":"journal-article","created":{"date-parts":[[2015,1,26]],"date-time":"2015-01-26T09:15:21Z","timestamp":1422263721000},"page":"606-613","source":"Crossref","is-referenced-by-count":21,"title":["The sonographic features of malignant mediastinal lymph nodes and a proposal for an algorithmic approach for sampling during endobronchial ultrasound"],"prefix":"10.1111","volume":"10","author":[{"given":"Ibrahim Onur","family":"Alici","sequence":"first","affiliation":[{"name":"Lung Transplantation Center Turkiye Yuksek Ihtisas Education and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6160-3778","authenticated-orcid":false,"given":"Nilg\u00fcn","family":"Y\u0131lmaz Demirci","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Diseases Gazi University Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayd\u0131n","family":"Y\u0131lmaz","sequence":"additional","affiliation":[{"name":"Interventional Pulmonology Unit Atat\u00fcrk Chest Diseases and Thoracic Surgery Education and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jale","family":"Karakaya","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Hacettepe University Faculty of Medicine Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esra","family":"\u00d6zayd\u0131n","sequence":"additional","affiliation":[{"name":"Department of Pathology Atat\u00fcrk Chest Diseases and Thoracic Surgery Education and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,3,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e3181a0d82e"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.09-2006"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440\u20101843.2012.02223.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-1016"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-0252"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440\u20101843.2012.02256"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2012.03.012"}],"container-title":["The Clinical Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcrj.12267","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/crj.12267","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T12:41:32Z","timestamp":1695472892000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/crj.12267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,3]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.1111\/crj.12267"],"URL":"https:\/\/doi.org\/10.1111\/crj.12267","archive":["Portico"],"relation":{},"ISSN":["1752-6981","1752-699X"],"issn-type":[{"type":"print","value":"1752-6981"},{"type":"electronic","value":"1752-699X"}],"subject":[],"published":{"date-parts":[[2015,3,3]]}}}