{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T16:29:26Z","timestamp":1780590566901,"version":"3.54.1"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,5,22]],"date-time":"2015-05-22T00:00:00Z","timestamp":1432252800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>Studies assessing hiatal hernia (<jats:styled-content style=\"fixed-case\">HH<\/jats:styled-content>)\u2010related effects on lung volumes derived by body plethysmography are limited. We aimed to evaluate the effect of hernia size on lung volumes (including assessment by body plethysmography) and the relationship to functional capacity, as well as the impact of corrective surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Seventy\u2010three patients (70\u2009\u00b1\u200910 years; 54 female) with large <jats:styled-content style=\"fixed-case\">HH<\/jats:styled-content> [mean\u2009\u00b1\u2009standard deviation, intra\u2010thoracic stomach (<jats:styled-content style=\"fixed-case\">ITS<\/jats:styled-content>) (%): 63\u2009\u00b1\u200920%; type <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> in 65\/73] had respiratory function data (spirometry, 73\/73; body plethysmography, 64\/73; diffusing capacity, 71\/73) and underwent <jats:styled-content style=\"fixed-case\">HH<\/jats:styled-content> surgery. Respiratory function was analysed in relation to hernia size (groups <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>: \u226450, 50%\u201375% and \u226575% <jats:styled-content style=\"fixed-case\">ITS<\/jats:styled-content>, respectively) and functional capacity. Post\u2010operative changes were quantified in a subgroup.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Total lung capacity (<jats:styled-content style=\"fixed-case\">TLC<\/jats:styled-content>) and vital capacity (<jats:styled-content style=\"fixed-case\">VC<\/jats:styled-content>) correlated inversely with hernia size (<jats:styled-content style=\"fixed-case\">TLC<\/jats:styled-content>: 97\u2009\u00b1\u200911%, 96\u2009\u00b1\u200913%, 88\u2009\u00b1\u200910% predicted in groups <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>, respectively, <jats:italic>P<\/jats:italic>\u2009=\u20090.01; <jats:styled-content style=\"fixed-case\">VC<\/jats:styled-content>: 110\u2009\u00b1\u200917%, 111\u2009\u00b1\u200914%, 98\u2009\u00b1\u200914% predicted, <jats:italic>P<\/jats:italic>\u2009=\u20090.02); however, mean values were normal and only 14% had abnormal lung volumes. Surgery increased <jats:styled-content style=\"fixed-case\">TLC<\/jats:styled-content> (93\u2009\u00b1\u200911% vs 97\u2009\u00b1\u200910% predicted) and <jats:styled-content style=\"fixed-case\">VC<\/jats:styled-content> (105\u2009\u00b1\u200915% vs 116\u2009\u00b1\u200918%), and decreased residual volume\/total lung capacity (<jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">TLC<\/jats:styled-content>) ratio (39\u2009\u00b1\u20097% vs 37\u2009\u00b1\u20096%) (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01 for all). Respiratory changes were modest relative to the marked functional class improvement. Among parameters that improved following <jats:styled-content style=\"fixed-case\">HH<\/jats:styled-content> surgery, decreased <jats:styled-content style=\"fixed-case\">TLC<\/jats:styled-content> and forced expiratory volume in 1\u2009s and increased <jats:styled-content style=\"fixed-case\">RV<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">TLC<\/jats:styled-content> ratio correlated with poorer functional class pre\u2010operatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Increasing <jats:styled-content style=\"fixed-case\">HH<\/jats:styled-content> size correlates with reduced <jats:styled-content style=\"fixed-case\">TLC<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">VC<\/jats:styled-content>. Surgery improves lung volumes and gas trapping; however, the changes are mild and within the normal range.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.12314","type":"journal-article","created":{"date-parts":[[2015,4,27]],"date-time":"2015-04-27T09:12:23Z","timestamp":1430125943000},"page":"139-150","source":"Crossref","is-referenced-by-count":17,"title":["Changes in lung volumes and gas trapping in patients with large hiatal hernia"],"prefix":"10.1111","volume":"11","author":[{"given":"Christopher","family":"Naoum","sequence":"first","affiliation":[{"name":"Department of Cardiology Concord Repatriation General Hospital The University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard","family":"Kritharides","sequence":"additional","affiliation":[{"name":"Department of Cardiology Concord Repatriation General Hospital The University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alvin","family":"Ing","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Concord Repatriation General Hospital The University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory L.","family":"Falk","sequence":"additional","affiliation":[{"name":"Department of Upper GI Surgery Concord Repatriation General Hospital The University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Yiannikas","sequence":"additional","affiliation":[{"name":"Department of Cardiology Concord Repatriation General Hospital The University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,5,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2012.04.058"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(02)03718-9"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2011.10.025"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-011-1768-0"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000193639"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000193640"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.07.013"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00034805"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00035005"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00034905"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.5.2101039"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00035205"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(11)60966-X"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-013-2397-9"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-013-3173-3"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.40.1.60"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2006.10.018"},{"key":"e_1_2_7_19_1","first-page":"335","article-title":"Obesity and respiratory diseases","volume":"3","author":"Zammit C","year":"2010","journal-title":"Int J Gen Med"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.3.857"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840200409"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-007-6627-3_23"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.158.6.9804105"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.06.00037005"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-198406000-00025"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arbres.2011.06.019"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-198009000-00019"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.108.5.1186"},{"key":"e_1_2_7_29_1","unstructured":"Australian Centre for Asthma Monitoring.Asthma in Australia 2011. 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