{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:28:24Z","timestamp":1788827304276,"version":"build-2803163510"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,7,8]],"date-time":"2015-07-08T00:00:00Z","timestamp":1436313600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Pulmonary infiltration and pleural effusion caused by permeability syndrome are the hallmark of pulmonary manifestation of dengue cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective and Methods<\/jats:title><jats:p>We report a 95\u2010year\u2010old chronic obstructive pulmonary disease case having dengue shock syndrome. Chest X\u2010ray examination revealed diffuse lung infiltration. However, bilateral pneumotoceles were unexpectedly found in computed tomography (CT) images. Dengue virus type 2 infection was confirmed by virus culture, serology and reverse transcriptase\u2010polymerase chain reaction. Profound shock with bilateral lung infiltration developed rapidly in 2 days with supportive care and empirical ampicillin\/ sulbactam. Bronchoscopy revealed a whitish plaque over bilateral upper bronchi. Biopsy via bronchoscopy revealed moulds with vascular invasion. Culture of bronchial alveolar lavage yielded <jats:italic>Aspergillus flavus<\/jats:italic>. The patient died despite amphotericin B treatment, which was started since finding the whitish plaque with bronchoscopy examination.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results and Conclusion<\/jats:title><jats:p>Besides to considering capillary leakage syndrome, our case report and literature review alert clinicians that CT and bronchoscopy may help to identify the true pathogen though all cases with concurrent dengue and Aspergillus infections had fatal outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.12323","type":"journal-article","created":{"date-parts":[[2015,6,15]],"date-time":"2015-06-15T09:15:22Z","timestamp":1434359722000},"page":"248-253","source":"Crossref","is-referenced-by-count":5,"title":["Fatal invasive aspergillosis: a rare co\u2010infection with an unexpected image presentation in a patient with dengue shock syndrome"],"prefix":"10.1111","volume":"11","author":[{"given":"Hui\u2010Ching","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Kaohsiung Medical University Hospital, Kaohsiung Medical University  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ko","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Kaohsiung Municipal Hsiao\u2010Kang Hospital  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po\u2010Liang","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Kaohsiung Medical University Hospital, Kaohsiung Medical University  Kaohsiung Taiwan"},{"name":"Department of Medicine, School of Medicine, College of Medicine Kaohsiung Medical University  Kaohsiung Taiwan"},{"name":"Division of Clinical Microbiology, Department of Laboratory Medicine Kaohsiung Medical University Hospital, Kaohsiung Medical University  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun\u2010Bow","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Pathology Kaohsiung Municipal Hsiao\u2010Kang Hospital  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huang\u2010Chi","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Kaohsiung Municipal Hsiao\u2010Kang Hospital  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,7,8]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2460"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2011.10-0476"},{"key":"e_1_2_4_4_1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.4269\/ajtmh.2007.77.151","article-title":"Acute respiratory failure in adult patients with dengue virus infection","volume":"77","author":"Wang CC","year":"2007","journal-title":"Am J Trop Med Hyg"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.6.2408-2416.2003"},{"key":"e_1_2_4_6_1","first-page":"642","article-title":"Current advances in dengue diagnosis","volume":"11","author":"Shu PY","year":"2004","journal-title":"Clin Diagn Lab Immunol"},{"key":"e_1_2_4_7_1","first-page":"315","volume-title":"PCR Protocols","author":"White TJ","year":"1990"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02464387"},{"key":"e_1_2_4_9_1","first-page":"1106","article-title":"Infection\u2010associated hemophagocytic syndrome among patients with dengue shock syndrome and invasive aspergillosis: a case series and review of the literature","volume":"42","author":"Larbcharoensub N","year":"2011","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"e_1_2_4_10_1","first-page":"389","article-title":"Invasive nosocomial aspergillosis associated with heart failure and complete heart block following recovery from dengue shock syndrome","volume":"8","author":"Kohli U","year":"2007","journal-title":"Pediatr Crit Care Med"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-200007000-00006"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2009.03015.x"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.10198"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.icb.7100008"},{"key":"e_1_2_4_15_1","first-page":"63","article-title":"Shift from a Th1\u2010type response to Th2\u2010type in dengue haemorrhagic fever","volume":"76","author":"Chaturvedi UC","year":"1999","journal-title":"Curr Sci India"},{"key":"e_1_2_4_16_1","doi-asserted-by":"crossref","first-page":"221","DOI":"10.4269\/ajtmh.2005.72.221","article-title":"Clinical characteristics and risk factors for concurrent bacteremia in adults with dengue hemorrhagic fever","volume":"72","author":"Lee IK","year":"2005","journal-title":"Am J Trop Med Hyg"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10238-012-0191-8"}],"container-title":["The Clinical Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcrj.12323","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcrj.12323","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/crj.12323","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T16:19:22Z","timestamp":1695572362000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/crj.12323"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,8]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1111\/crj.12323"],"URL":"https:\/\/doi.org\/10.1111\/crj.12323","archive":["Portico"],"relation":{},"ISSN":["1752-6981","1752-699X"],"issn-type":[{"value":"1752-6981","type":"print"},{"value":"1752-699X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,8]]}}}