{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T16:22:18Z","timestamp":1790266938702,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,11,18]],"date-time":"2015-11-18T00:00:00Z","timestamp":1447804800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Institute of Tuberculosis and Lung Diseases Research in Warsaw"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to identify the frequency and prevalence of comorbidities in sarcoid patients and to assess their influence on overall mortality in the cohort of patients with sarcoidosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>A cohort of 557 patients with histologically confirmed sarcoidosis diagnosed between 2007 and 2011 and a group of non\u2010sarcoid controls were observed. All patients were carefully observed for comorbidities and mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>291 males (52.2%) and 266 females (47.8%) with mean age 48.4\u2009\u00b1\u200912.0 years in sarcoidosis group and a group of 100 controls with mean age (49.25\u2009\u00b1\u200910.3) were observed. The mean number of comorbidities in both groups was similar (0.9\u2009\u00b1\u20090.99 vs 0.81\u2009\u00b1\u20090.84 NS). The frequency of thyroid disease was significantly higher in sarcoidosis group comparing to controls at the time of diagnosis (OR\u2009=\u20093.62 <jats:italic>P<\/jats:italic>\u2009=\u20090.0144). During the observation period (median 58.0 months), 16 patients died (2.9%). The mean number of comorbidities was significantly higher in the groups of non\u2010survivors as compared to survivors (2.8\u2009\u00b1\u20091.0, vs 0.8\u2009\u00b1\u20090.9), <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The comorbidity burden has strong impact on mortality in sarcoidosis. Thyroid diseases are more frequent in sarcoidosis than in non\u2010sarcoid controls.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.12398","type":"journal-article","created":{"date-parts":[[2015,10,16]],"date-time":"2015-10-16T09:02:45Z","timestamp":1444986165000},"page":"648-656","source":"Crossref","is-referenced-by-count":42,"title":["The influence of comorbidities on mortality in sarcoidosis: a observational prospective cohort study"],"prefix":"10.1111","volume":"11","author":[{"given":"Adam","family":"Nowi\u0144ski","sequence":"first","affiliation":[{"name":"2nd Department of Respiratory Medicine National Institute of Tuberculosis and Lung Diseases Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elzbieta","family":"Pu\u015bci\u0144ska","sequence":"additional","affiliation":[{"name":"2nd Department of Respiratory Medicine National Institute of Tuberculosis and Lung Diseases Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Goljan","sequence":"additional","affiliation":[{"name":"2nd Department of Respiratory Medicine National Institute of Tuberculosis and Lung Diseases Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Peradzynska","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Medical University of Warsaw Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Bednarek","sequence":"additional","affiliation":[{"name":"2nd Department of Respiratory Medicine National Institute of Tuberculosis and Lung Diseases Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damian","family":"Korzybski","sequence":"additional","affiliation":[{"name":"2nd Department of Respiratory Medicine National Institute of Tuberculosis and Lung Diseases Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dariusz","family":"Kami\u0144ski","sequence":"additional","affiliation":[{"name":"2nd Department of Respiratory Medicine National Institute of Tuberculosis and Lung Diseases Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Stok\u0142osa","sequence":"additional","affiliation":[{"name":"2nd Department of Respiratory Medicine National Institute of Tuberculosis and Lung Diseases Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Czystowska","sequence":"additional","affiliation":[{"name":"2nd Department of Respiratory Medicine National Institute of Tuberculosis and Lung Diseases Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawel","family":"\u015aliwi\u0144ski","sequence":"additional","affiliation":[{"name":"4th Department of Respiratory Medicine National Institute of Tuberculosis and Lung Diseases Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorota","family":"G\u00f3recka","sequence":"additional","affiliation":[{"name":"2nd Department of Respiratory Medicine National Institute of Tuberculosis and Lung Diseases Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,11,18]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.160.2.ats4-99"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1513\/pats.200608-155MS"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201201-0034OC"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2009.131078"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/postgradmedj-2013-132186"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.83.1.128"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5261.1165"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00133805"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.128.4.2099"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.97.10122794"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00128008"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1781(92)90005-N"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(74)90160-0"},{"key":"e_1_2_7_16_1","first-page":"29","article-title":"Sarcoidosis: epidemiology and prognosis. 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