{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T10:45:10Z","timestamp":1761648310295},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,1,24]],"date-time":"2016-01-24T00:00:00Z","timestamp":1453593600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label \/><jats:p>Pleural epithelioid haemangioendothelioma (EHE) is a rare tumour that originates in the vascular endothelium with an intermediate degree of malignancy between haemangioma and angiosarcoma. Smoking and asbestos exposure are unproven risk factors and diagnosis is usually confirmed by thoracoscopy, since pleural fluid (PF) cytology is often not conclusive. Immunohistochemistry can also help to confirm the diagnosis. We report an 85\u2010year\u2010old patient with bilateral pleural EHE diagnosed by thoracoscopy, who debuted with a spontaneous bilateral haemothorax, the second described so far, and we conducted a thorough review of the literature to describe the clinical, radiological and prognostic features, as well as the PF, of this rare tumour.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.12421","type":"journal-article","created":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T07:06:55Z","timestamp":1448953615000},"page":"1079-1085","source":"Crossref","is-referenced-by-count":9,"title":["Spontaneous bilateral haemothorax as presentation of primary pleural epithelioid haemangioendothelioma"],"prefix":"10.1111","volume":"11","author":[{"given":"Luc\u00eda","family":"Ferreiro","sequence":"first","affiliation":[{"name":"Department of Pulmonology University of Santiago Hospital Complex Santiago de Compostela Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther","family":"San\u2010Jos\u00e9","sequence":"additional","affiliation":[{"name":"Department of Clinical Analysis University of Santiago Hospital Complex Santiago de Compostela Spain"},{"name":"Interdisciplinary Pulmonology Research Group Health Research Institute of Santiago (IDIS), University of Santiago Hospital Complex Santiago de Compostela Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Su\u00e1rez\u2010Antelo","sequence":"additional","affiliation":[{"name":"Department of Pulmonology University of Santiago Hospital Complex Santiago de Compostela Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ihab","family":"Abdulkader","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Santiago Hospital Complex Santiago de Compostela Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anxo","family":"Mart\u00ednez\u2010de\u2010Alegr\u00eda","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Santiago Hospital Complex Santiago de Compostela Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco\u2010Javier","family":"Gonz\u00e1lez\u2010Barcala","sequence":"additional","affiliation":[{"name":"Department of Pulmonology University of Santiago Hospital Complex Santiago de Compostela Spain"},{"name":"Interdisciplinary Pulmonology Research Group Health Research Institute of Santiago (IDIS), University of Santiago Hospital Complex Santiago de Compostela Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Vald\u00e9s","sequence":"additional","affiliation":[{"name":"Department of Pulmonology University of Santiago Hospital Complex Santiago de Compostela Spain"},{"name":"Interdisciplinary Pulmonology Research Group Health Research Institute of Santiago (IDIS), University of Santiago Hospital Complex Santiago de Compostela Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,1,24]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.175.6.1751545"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr.01.2012.5527"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-194309000-00014"},{"issue":"5","key":"e_1_2_5_5_1","first-page":"459","article-title":"Unusual thoracic manifestations of epithelioid hemangioendothelioma","volume":"111","author":"Yousem SA","year":"1987","journal-title":"Arch Pathol Lab Med."},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199612000-00001"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3003.1999.14a40.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.55.10.860"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-37132004000100012"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2004.018937"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0873-2159(15)30440-2"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-005-0059-3"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.20620"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2008.49.6.1036"},{"issue":"2","key":"e_1_2_5_15_1","first-page":"73","article-title":"Hemangioendotelioma epitelioide de pleura. Presentacion de un caso con hemotorax","volume":"8","author":"Martinez D","year":"2008","journal-title":"Rev Arg Med Resp."},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2009.11.008"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.09-2439"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0873-2159(15)30044-1"},{"issue":"3","key":"e_1_2_5_19_1","first-page":"135","article-title":"Primary pleural haemangioendothelioma in an Italian female patient: a case report and review of the literature","volume":"73","author":"Bocchino M","year":"2010","journal-title":"Monaldi Arch Chest Dis."},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1752-699X.2010.00221.x"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.05.070"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2011.04.003"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-012-9377-9"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocs.12094"},{"issue":"1","key":"e_1_2_5_25_1","first-page":"82","article-title":"Endothelial cell markers CD31, CD34, and BNH9 antibody to H\u2010 and Y\u2010antigens \u2013 evaluation of their specificity and sensitivity in the diagnosis of vascular tumors and comparison with von Willebrand factor","volume":"7","author":"Miettinen M","year":"1994","journal-title":"Mod Pathol."},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/gcc.20886"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/88.3.286"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199001000-00007"}],"container-title":["The Clinical Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcrj.12421","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcrj.12421","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/crj.12421","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T13:49:55Z","timestamp":1695563395000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/crj.12421"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1,24]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1111\/crj.12421"],"URL":"https:\/\/doi.org\/10.1111\/crj.12421","archive":["Portico"],"relation":{},"ISSN":["1752-6981","1752-699X"],"issn-type":[{"value":"1752-6981","type":"print"},{"value":"1752-699X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1,24]]}}}