{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T20:26:45Z","timestamp":1792268805844,"version":"4.4.0"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,2,24]],"date-time":"2016-02-24T00:00:00Z","timestamp":1456272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Endobronchial ultrasound\u2010guided transbronchial needle aspiration (EBUS\u2010TBNA) is a new, minimally invasive, bronchoscopic technique used in the evaluation of inthrathoracic lymph nodes.Use of sedation drugs before the procedure differs among centres. There is no standardization about sedation before EBUS\u2010TBNA.We used a policy decision to shift from use of propofol with midazolam vs midazolam alone in a large tertiary hospital to evaluate the diagnostic yield and safety of EBUS\u2010TBNA procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Files of all the patients who were performed EBUS\u2010TBNA between the dates of September 2010 and May 2014 were surveyed. All the EBUS\u2010TBNA cases were performed under sedation of propofol and midazolam with an accompanying anesthesiologist in the beginning, however, sedation is applied with midazolam without an accompanying anesthesiologist after April 2013 due to changes in sedation policy. The diagnostic yield and complication rates were compared by chi\u2010squared analysis between two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The files of 340 EBUS\u2010TBNA performed patients were evaluated. Of the patients 274 eligible patients were analysed. 152 patients who fulfilled the inclusion criteria were analysed in propofol\u2010midazolam (P) sedated group and 122 patients were analysed in midazolam (M) group. There is no statistically significant difference between two different sedated groups in terms of age and gender. Diagnostic value was detected as 77.6% in P group and 85.7% in M group and the difference was not statistically significant. No difference between complication rates of both groups was observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Both sedation\u2010types for performing EBUS\u2010TBNA showed similar diagnostic value and complication rates in our study. Propofol with midazolam application requires with an accompanying anaesthesiologist, therefore, it increases cost. EBUS\u2010TBNA procedures had been performed in safe with no decrease in diagnostic yield under moderate sedation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.12442","type":"journal-article","created":{"date-parts":[[2015,12,31]],"date-time":"2015-12-31T16:00:41Z","timestamp":1451577641000},"page":"935-941","source":"Crossref","is-referenced-by-count":20,"title":["A comparison of propofol\u2013midazolam and midazolam alone for sedation in endobronchial ultrasound\u2010guided transbronchial needle aspiration: a retrospective cohort study"],"prefix":"10.1111","volume":"11","author":[{"given":"Selahattin","family":"\u00d6zta\u015f","sequence":"first","affiliation":[{"name":"Chest Department S\u00fcreyyapa\u015fa Chest Disease and Thoracic Surgery Education and Research Hospital \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00dclk\u00fc","family":"Aka Akt\u00fcrk","sequence":"additional","affiliation":[{"name":"Chest Department S\u00fcreyyapa\u015fa Chest Disease and Thoracic Surgery Education and Research Hospital \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Levent A.","family":"Alpay","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Department S\u00fcreyyapa\u015fa Chest Disease and Thoracic Surgery Education and Research Hospital \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burhan","family":"Meydan","sequence":"additional","affiliation":[{"name":"Anestesiology Department S\u00fcreyyapa\u015fa Chest Disease and Thoracic Surgery Education and Research Hospital \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamza","family":"Og\u00fcn","sequence":"additional","affiliation":[{"name":"Chest Department S\u00fcreyyapa\u015fa Chest Disease and Thoracic Surgery Education and Research Hospital \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mah\u015fuk","family":"Taylan","sequence":"additional","affiliation":[{"name":"Chest Department Dicle University Diyarbak\u0131r Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Yal\u00e7\u0131nsoy","sequence":"additional","affiliation":[{"name":"Chest Department Malatya \u0130n\u00f6n\u00fc University Medicine Faculty Malatya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haluk C.","family":"\u00c7al\u0131\u015f\u0131r","sequence":"additional","affiliation":[{"name":"Chest Department Private Acibadem Hospital \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Metin","family":"G\u00f6rg\u00fcner","sequence":"additional","affiliation":[{"name":"Chest Department Private Emsay Hospital \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilek","family":"Ernam","sequence":"additional","affiliation":[{"name":"Chest Department S\u00fcreyyapa\u015fa Chest Disease and Thoracic Surgery Education and Research Hospital \u0130stanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,2,24]]},"reference":[{"issue":"6","key":"e_1_2_6_2_1","first-page":"702","article-title":"Patient satisfaction during endobronchial ultrasound\u2010guided transbronchial needle aspiration performed under conscious sedation","volume":"55","author":"Steinfort DP","year":"2010","journal-title":"Respir Care."},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2007.09.017"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0623"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.10-3361"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.03.00118302"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/145.1.233"},{"issue":"1","key":"e_1_2_6_8_1","first-page":"11","article-title":"British Thoracic Society guidelines on diagnostic flexible bronchoscopy","volume":"56","author":"British Thoracic Society Bronchoscopy Gu\u0131idelines Committee, a subcommittee of the Standards of Care Committee of the British Thoracic Society.","year":"2001","journal-title":"Thorax."},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5920.656"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.111.6.1718"},{"issue":"3","key":"e_1_2_6_11_1","first-page":"1","article-title":"British Thoracic Society guideline for advanced diagnostic and therapeutic flexible bronchoscopy in adults","volume":"66","author":"DuRand IA","year":"2011","journal-title":"Thorax"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00180808"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2003.019836"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00121610"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201209-074OC"},{"issue":"2","key":"e_1_2_6_16_1","first-page":"A94","article-title":"Patient satisfaction during endobronchial ultrasound\u2010guided transbronchial needle aspiration performed under mild conscious sedation (abstract)","volume":"67","author":"Jeyabalan A","year":"2012","journal-title":"Thorax."},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rca.2013.01.006"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201409-1615OC"}],"container-title":["The Clinical Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcrj.12442","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcrj.12442","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/crj.12442","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T13:51:34Z","timestamp":1695563494000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/crj.12442"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,24]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1111\/crj.12442"],"URL":"https:\/\/doi.org\/10.1111\/crj.12442","archive":["Portico"],"relation":{},"ISSN":["1752-6981","1752-699X"],"issn-type":[{"value":"1752-6981","type":"print"},{"value":"1752-699X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,24]]}}}