{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T11:45:33Z","timestamp":1695642333509},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,2,15]],"date-time":"2016-02-15T00:00:00Z","timestamp":1455494400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Chronic obstructive pulmonary disease (COPD) remains a globally significant cause of mortality, although COPD mortality varies from country to country, and across different regions within each country. The primary objective of this study was to determine the mortality rates of COPD patients who present with acute respiratory failure (ARF) to a tertiary care referral center in different stages of their follow\u2010up (ICU, in\u2010hospital and after discharge). The secondary objective was to determine factors associated with mortality in this group of patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Medical records of consecutive COPD patients over a 10\u2010year period were reviewed.The study included 147 patients. Of these, 72 were treated initially with noninvasive positive pressure ventilation (NIPPV), and 12 of these required intubation after NIPPV failed. Therefore, 86 patients were intubated for invasive mechanical ventilation (IMV), while NIPPV was succesful in 60 patients. Survival time was independently associated with advanced age, high APACHE II score, co\u2010morbidity and the need for IMV. The cumulative mortality was 27% in the medical ICU and 31% in hospital following ICU discharge. The mortality rate at 1, 2 and 5 years was 54%, 66% and 84%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>COPD patients admitted to the ICU for ARF have an approximately 70% chance of leaving hospital alive, but half of these may die in the first 6 months after discharge. The risk factors related to mortality were advanced age, high APACHE II score, co\u2010morbidity and IMV requirement.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.12450","type":"journal-article","created":{"date-parts":[[2016,1,18]],"date-time":"2016-01-18T22:44:37Z","timestamp":1453157077000},"page":"975-982","source":"Crossref","is-referenced-by-count":4,"title":["Long\u2010term outcome of chronic obstructive pulmonary disease patients with acute respiratory failure following intensive care unit discharge in <scp>T<\/scp>urkey"],"prefix":"10.1111","volume":"11","author":[{"given":"Serpil","family":"Ocal","sequence":"first","affiliation":[{"name":"Hacettepe University, Faculty of Medicine Medical Intensive Care Unit Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ebru","family":"Ortac Ersoy","sequence":"additional","affiliation":[{"name":"Hacettepe University, Faculty of Medicine Medical Intensive Care Unit Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ozge","family":"Ozturk","sequence":"additional","affiliation":[{"name":"Hacettepe University, Faculty of Medicine Department of Chest Diseases Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mutlu","family":"Hayran","sequence":"additional","affiliation":[{"name":"Hacettepe University, Faculty of Medicine Department of Preventive Oncology Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arzu","family":"Topeli","sequence":"additional","affiliation":[{"name":"Hacettepe University, Faculty of Medicine Medical Intensive Care Unit Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lutfi","family":"Coplu","sequence":"additional","affiliation":[{"name":"Hacettepe University, Faculty of Medicine Department of Chest Diseases Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,15]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-2918"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61377-4"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2005.040527"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.14-0655"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000233859.01815.38"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201106-1094OC"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31828a2bd8"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200703-456SO"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.92.6.971"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.95.2.398"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.104.4.1222"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.104.3.854"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1995.03530230038027"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0954-6111(98)90088-9"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199801000-00019"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001340050879"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.119.6.1840"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.2.459"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-2896(04)75528-3"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2007.091249"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.128.2.518"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2010.02.006"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-37132011000200012"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S37611"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.94.07091645"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.154.4.8887592"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.57.1.29"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2007.06.028"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/2049-6958-6-2-92"},{"key":"e_1_2_5_31_1","unstructured":"KocabasA HanciogluA TurkyilmazS.Prevalance of COPD in Adana Turkey (BOLD\u2010Turkey study. In Proceedings of the American Thoracic Society2006; 3: A543."},{"key":"e_1_2_5_32_1","first-page":"3","article-title":"Kronik obstruktif akci\u011fer hastal\u0131\u011f\u0131 \u00fczerinde epidemiyolojik bir ara\u015ft\u0131rma","volume":"24","author":"Baykal Y.","year":"1976","journal-title":"T\u00fcberk\u00fcloz veToraks."},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.14-1216"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199710000-00018"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-004-2320-7"},{"key":"e_1_2_5_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2004.01.009"},{"key":"e_1_2_5_37_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/56.3.M146"},{"key":"e_1_2_5_38_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00114307"},{"key":"e_1_2_5_39_1","doi-asserted-by":"publisher","DOI":"10.1513\/pats.200708-142ET"}],"container-title":["The Clinical Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcrj.12450","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcrj.12450","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/crj.12450","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T13:50:45Z","timestamp":1695563445000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/crj.12450"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,15]]},"references-count":38,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1111\/crj.12450"],"URL":"https:\/\/doi.org\/10.1111\/crj.12450","archive":["Portico"],"relation":{},"ISSN":["1752-6981","1752-699X"],"issn-type":[{"value":"1752-6981","type":"print"},{"value":"1752-699X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,15]]}}}