{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T20:26:42Z","timestamp":1790368002823,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,6,22]],"date-time":"2016-06-22T00:00:00Z","timestamp":1466553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Common variable immunodeficiency (CVID) is one of the most common primary immunodeficiencies, which is characterized by reduced serum immunoglobulin levels and B\u2010lymphocyte dysfunction. There are many clinical manifestations of this disease, the most common of which are recurrent respiratory tract infections. Among the most recently recognized autoimmune manifestation of CVID is a disease described as granulomatous\u2010lymphocytic interstitial lung disease (GLILD), where CVID coexists with a small airway lymphoproliferative disorder, mimicking follicular bronchiolitis, or lymphocytic interstitial pneumonitis (LIP) on histology specimens. We herein describe the clinical and radiological features of GLILD in a 55\u2010year\u2010old woman where the diagnosis of CVID was actively pursued and eventually confirmed after her lung biopsy showed characteristic features of GLILD. The patient had dramatic response to treatment with IVIG and corticosteroids for 3 months followed by Mycophenolate mofetil for maintenance therapy.<\/jats:p>","DOI":"10.1111\/crj.12511","type":"journal-article","created":{"date-parts":[[2016,5,31]],"date-time":"2016-05-31T11:48:37Z","timestamp":1464695317000},"page":"337-343","source":"Crossref","is-referenced-by-count":30,"title":["Granulomatous\u2010lymphocytic interstitial lung disease as the first manifestation of common variable immunodeficiency"],"prefix":"10.1111","volume":"12","author":[{"given":"Basheer","family":"Tashtoush","sequence":"first","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Cleveland Clinic Florida Weston Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roya","family":"Memarpour","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Cleveland Clinic Florida Weston Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Ramirez","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Cleveland Clinic Florida Weston Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Bejarano","sequence":"additional","affiliation":[{"name":"Department of Pathology Cleveland Clinic Florida Weston Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinesh","family":"Mehta","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Cleveland Clinic Florida Weston Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,6,22]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"577","article-title":"Common variable immunodeficiency. 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