{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:33:47Z","timestamp":1761863627092},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,9,27]],"date-time":"2016-09-27T00:00:00Z","timestamp":1474934400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Pulmonary thromboembolism (PTE) remains under\u2010diagnosed fatal disease at emergency units suggesting the need for alternative, easy, and noninvasive bedside diagnostic approaches.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine the diagnostic role of gray\u2010scale and color Doppler transthoracic ultrasonography (TUS) in patients with PTE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>Blinded to 64 multi\u2010detectors CT pulmonary angiography (MDCTPA) examination as a gold standard, 60 patients with clinically suspected PTE underwent gray\u2010scale and then color Doppler TUS examination. Results were compared and diagnostic accuracy of TUS was assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty patients proved to have PTE by MDCTPA. TUS showed typical lesions in 33 patients with the mean of 2 lesions per patient. Most lesions were hypoechoic, wedge\u2010 shaped, and pleural\u2010 based and the majority (80%) was located in the lower lobes. Consolidation with little perfusion was detected by Color Doppler ultrasound in 97% of lesions. Isolated central PTE was significantly higher in TUS negative patients. For gray \u2013scale TUS, sensitivity, specificity, positive and negative predictive values and accuracy were 82%, 90%, 94%, 72%, and 85%. Meanwhile the sensitivity, specificity, positive and negative predictive values and accuracy of color Doppler TUS were 80%, 95%, 97%, 70% and 87%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>TUS is a reliable diagnostic bedside test for PTE in critically ill and immobile patients. Adding color Doppler to gray\u2013scale TUS increases the specificity and accuracy and consequently the confidence in the diagnosis of peripheral pulmonary infarctions and differentiates them from other pulmonary lesions that allow initiation of anticoagulants.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.12547","type":"journal-article","created":{"date-parts":[[2016,9,8]],"date-time":"2016-09-08T23:30:08Z","timestamp":1473377408000},"page":"474-482","source":"Crossref","is-referenced-by-count":7,"title":["Acute pulmonary thromboembolism in emergency room: gray\u2010scale versus color doppler ultrasound evaluation"],"prefix":"10.1111","volume":"12","author":[{"given":"Maha Kamel","family":"Ghanem","sequence":"first","affiliation":[{"name":"Chest Department Assiut University Hospital  Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hoda Ahmed","family":"Makhlouf","sequence":"additional","affiliation":[{"name":"Chest Department Assiut University Hospital  Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali Abdel\u2010Azeem","family":"Hasan","sequence":"additional","affiliation":[{"name":"Chest Department Assiut University Hospital  Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed Atef","family":"Alkarn","sequence":"additional","affiliation":[{"name":"Chest Department Assiut University Hospital  Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,9,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.120.6.1977"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0885066610392658"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.47.1085"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2003.22.7.673"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199612123352407"},{"key":"e_1_2_10_7_1","first-page":"1487","article-title":"Diagnosis of pulmonary embolism by transthoracic sonography. 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