{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T11:20:48Z","timestamp":1768908048496,"version":"3.49.0"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,11,10]],"date-time":"2016-11-10T00:00:00Z","timestamp":1478736000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aim of this study was to evaluate the relationship of the pre\u2010treatment blood neutrophil\/lymphocyte count ratio (NLR) with the maximum standard uptake value (SUVmax) of primary masses on positron emission tomography\/computed tomography (PET\/CT) taken before treatment in patients diagnosed with malignant pleural mesothelioma (MPM) and to evaluate the contribution to prognosis. A retrospective evaluation was made of 73 patients diagnosed with MPM in our hospital between January 2006 and January 2014. The SUVmax value of the primary mass on pre\u2010treatment PET\/CT, the haemogram parameters (Hb, Hct, NLR, MPV, PLT) at the time of diagnosis, the progression history, the date of the final visit, and the date of death of exitus patients was recorded from patient files PET\/CT. The study group comprised 37 males (50.7%) with a mean age of 56.1\u2009\u00b1\u200911.4 years. The median survival time of these patients was 13 months. The survival time of the patient group aged &lt;55 years was significantly longer (<jats:italic>P<\/jats:italic>\u2009=\u2009.006). Although the survival time of patients with NLR\u2009&lt;\u20093 and SUVmax\u2009&lt;\u20095 was longer, the difference was not statistically significant (<jats:italic>P<\/jats:italic>\u2009=\u2009.63, <jats:italic>P<\/jats:italic>\u2009=\u20090.08). A statistically significant difference was determined between the mean (or median) SUVmax values of the patient groups with NLR\u2009&lt;\u20093 and NLR \u22653 (<jats:italic>P<\/jats:italic>\u2009=\u2009.019) with the SUVmax value of the NLR\u2009&lt;\u20093 group found to be low. In conclusion, in patients with MPM, NLR \u22653 and high SUVmax values at the time of diagnosis can be considered an indicator of poor prognosis but are not a guide in the prediction of progression.<\/jats:p>","DOI":"10.1111\/crj.12574","type":"journal-article","created":{"date-parts":[[2016,10,21]],"date-time":"2016-10-21T18:09:49Z","timestamp":1477073389000},"page":"646-651","source":"Crossref","is-referenced-by-count":9,"title":["Relation between neutrophil\/lymphocyte ratio and primary tumor metabolic activity in patients with malign pleural mesothelioma"],"prefix":"10.1111","volume":"12","author":[{"given":"Berna Ak\u0131nc\u0131","family":"\u00d6zy\u00fcrek","sequence":"first","affiliation":[{"name":"Chest Diseases Clinic Ataturk Chest Diseases and Chest Surgery Education and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6zlem","family":"\u00d6zmen","sequence":"additional","affiliation":[{"name":"Nuclear Medicine Clinic Ataturk Chest Diseases and Chest Surgery Education and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tu\u011f\u00e7e \u015eahin","family":"\u00d6zdemirel","sequence":"additional","affiliation":[{"name":"Chest Diseases Clinic Ataturk Chest Diseases and Chest Surgery Education and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yurdanur","family":"Erdo\u011fan","sequence":"additional","affiliation":[{"name":"Chest Diseases Clinic Ataturk Chest Diseases and Chest Surgery Education and Research Hospital Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bekir","family":"Kaplan","sequence":"additional","affiliation":[{"name":"TC Ministry of Health, General Directorate of Health Research Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tu\u011fba","family":"Kaplan","sequence":"additional","affiliation":[{"name":"Chest Diseases Ulus 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