{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:47:33Z","timestamp":1787014053828,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,1,12]],"date-time":"2017-01-12T00:00:00Z","timestamp":1484179200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Pulmonary hypertension (PH) is common complication in advanced lung disease. Echocardiography provides additional information and may be useful to assess PH probability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The usefulness of combination of well\u2010known echocardiographic parameters in detecting PH in patients with advanced lung disease referred for lung transplantation was evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study population consisted of 37 consecutive patients with idiopathic pulmonary fibrosis (IPF), 20 patients with chronic obstructive pulmonary disease (COPD), and 8 patients with other interstitial lung diseases. PH was defined as mean pulmonary arterial pressure (mPAP) \u226525 mm Hg diagnosed by cardiac catheterization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      PH was present in 67.6% of enrolled IPF patients, 30% of enrolled COPD patients, and 75% of patients with other interstitial lung diseases. The receiver operating characteristics (ROC) curve analysis demonstrated right ventricular systolic pressure (RVSP\n                      <jats:bold>)<\/jats:bold>\n                      \u226543 mm Hg to be the threshold for PH prediction (n\u2009=\u200937, sensitivity 92.3%, specificity 81.8%, area under curve (AUC) 0.84, 95% confidence interval (CI) 0.67\u20101.0;\n                      <jats:italic>P =<\/jats:italic>\n                      .019). Right ventricular outflow tract (RVOT) diameter \u226534 mm and tricuspid annular plane systolic excursion (TAPSE) \u226418 mm had acceptable sensitivity, specificity and AUC (n\u2009=\u200965, 62.2%, 89.3%, 0.77, 95% CI 0.66\u20100.89;\n                      <jats:italic>P =<\/jats:italic>\n                      .11 and n\u2009=\u200962, 77.1%, 66.7%, 0.74, CI 0.61\u20100.87;\n                      <jats:italic>P =<\/jats:italic>\n                      .27, respectively). Combination of RVSP, RVOT and TAPSE, obtained in 36 patients, increased the sensitivity and negative predictive value (NPV) to 100%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In patients with advanced lung diseases referred for lung transplantation the combination of RVSP, RVOT diameter, and TAPSE may be helpful in PH exclusion.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/crj.12608","type":"journal-article","created":{"date-parts":[[2017,1,4]],"date-time":"2017-01-04T03:26:52Z","timestamp":1483500412000},"page":"930-938","source":"Crossref","is-referenced-by-count":30,"title":["Pulmonary hypertension in advanced lung diseases: Echocardiography as an important part of patient evaluation for lung transplantation"],"prefix":"10.1111","volume":"12","author":[{"given":"Jolanta","family":"Nowak","sequence":"first","affiliation":[{"name":"3rd Department of Cardiology SMDZ in Zabrze, Medical University of Silesia in Katowice, Silesian Centre for Heart Diseases Zabrze Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3880-5325","authenticated-orcid":false,"given":"Bartosz","family":"Hudzik","sequence":"additional","affiliation":[{"name":"3rd Department of Cardiology SMDZ in Zabrze, Medical University of Silesia in Katowice, Silesian Centre for Heart Diseases Zabrze Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dariusz","family":"Jastrz\u0229bski","sequence":"additional","affiliation":[{"name":"Department of Lung Diseases and Tuberculosis SMDZ in Zabrze, Medical University of Silesia in Katowice Zabrze Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacek T.","family":"Niedziela","sequence":"additional","affiliation":[{"name":"3rd Department of Cardiology SMDZ in Zabrze, Medical University of Silesia in Katowice, Silesian Centre for Heart Diseases Zabrze Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Rozentryt","sequence":"additional","affiliation":[{"name":"3rd Department of Cardiology SMDZ in Zabrze, Medical University of Silesia in Katowice, Silesian Centre for Heart Diseases Zabrze Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacek","family":"Wojarski","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery and Transplantology SMDZ in Zabrze, Medical University of Silesia in Katowice, Silesian Centre for Heart Diseases Zabrze Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Ochman","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery and Transplantology SMDZ in Zabrze, Medical 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