{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:25:49Z","timestamp":1776731149078,"version":"3.51.2"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,8,14]],"date-time":"2017-08-14T00:00:00Z","timestamp":1502668800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002560","name":"Soonchunhyang University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002560","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>A limited number of studies have investigated the relationships among fatigue, insomnia and obstructive sleep apnea (OSA). This study evaluated the factors affecting fatigue severity in patients with OSA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We investigated 633 OSA patients who were diagnosed by polysomnography. All patients completed sleep questionnaires including self\u2010reported sleep duration, the Fatigue Severity Scale (FSS), the Korean version of Epworth Sleepiness Scale (K\u2010ESS), Insomnia Severity Index (ISI), Korean version of Pittsburgh Sleep Quality Index (K\u2010PSQI) and Beck Depression Inventory\u20102 (BDI\u20102).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The subjects had a mean age of 48.7\u2009\u00b1\u200910.5 years and 72.5% (n\u2009=\u2009459) were men. The subjects were distributed as follows: 160 with mild, 168 with moderate and 305 with severe OSA. A multiple regression model found that age (\u03b2\u2009=\u2009\u22120.146, <jats:italic>P<\/jats:italic>\u2009=\u2009.005), K\u2010ESS (\u03b2\u2009=\u20090.689, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), 8\u2009\u2264\u2009ISI score\u2009&lt;\u200915 (\u03b2\u2009=\u20093.801, <jats:italic>P<\/jats:italic>\u2009=\u2009.006), 15\u2009\u2264\u2009ISI score (\u03b2\u2009=\u20094.565, <jats:italic>P<\/jats:italic>\u2009=\u2009.009), and K\u2010PSQI (\u03b2\u2009=\u20090.684, <jats:italic>P<\/jats:italic>\u2009=\u2009.002) were predictors of a higher FSS score. BDI\u20102 (\u03b2\u2009=\u20090.007, <jats:italic>P<\/jats:italic>\u2009=\u2009.918), apnea\u2010hypopnea index (AHI) (\u03b2\u2009=\u2009\u22120.006, <jats:italic>P<\/jats:italic>\u2009=\u2009.895), arousal index (\u03b2\u2009=\u20090.034, <jats:italic>P<\/jats:italic>\u2009=\u2009.415), and nadir O<jats:sub>2<\/jats:sub> saturation (\u03b2\u2009=\u2009\u22120.044, <jats:italic>P<\/jats:italic>\u2009=\u2009.655) were not associated with FSS score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our findings indicate that fatigue severity is more likely to be associated with younger age, sleepiness and insomnia, but less likely to be directly related to OSA severity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.12682","type":"journal-article","created":{"date-parts":[[2017,8,4]],"date-time":"2017-08-04T11:16:25Z","timestamp":1501845385000},"page":"1045-1051","source":"Crossref","is-referenced-by-count":15,"title":["Factors affecting fatigue severity in patients with obstructive sleep apnea"],"prefix":"10.1111","volume":"11","author":[{"given":"Soo A","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Soonchunhyang University College of Medicine, Cheonan Hospital Cheonan South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian B","family":"Koo","sequence":"additional","affiliation":[{"name":"Department of Neurology Yale University School of Medicine New Haven Connecticut"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Do Eui","family":"Kim","sequence":"additional","affiliation":[{"name":"Sleep Disorders Center Department of Neurology, Soonchunhyang University College of Medicine, Cheonan Hospital Cheonan South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young","family":"Hwangbo","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine Soonchunhyang University College of Medicine Cheonan South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6343-6520","authenticated-orcid":false,"given":"Kwang Ik","family":"Yang","sequence":"additional","affiliation":[{"name":"Sleep Disorders Center Department of Neurology, Soonchunhyang University College of Medicine, Cheonan Hospital Cheonan South 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