{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T08:45:56Z","timestamp":1772268356926,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,11,24]],"date-time":"2017-11-24T00:00:00Z","timestamp":1511481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction and Objectives<\/jats:title><jats:p>Endosonography has become standard of care in the diagnostic work\u2010up of mediastinal lymphadenopathy and peribronchial lung lesions, but its success rate in some specific settings\/conditions may be hampered by limited needle flexibility and size. We report on our initial experience with the 19G Flex needle, characterized by larger size and greater flexibility as compared with the currently available cytology needles.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective review of prospectively collected data on the first 13 consecutive patients submitted to endosonography with the 19G Flex needle. Patients were included if they had: (<jats:italic>a<\/jats:italic>) suspicion of a histologically complex disease (ie, lymphoma); (<jats:italic>b<\/jats:italic>) suspicion of an advanced lung cancer possibly requiring extensive genotyping; (<jats:italic>c<\/jats:italic>) a lesion whose sampling with a 22G needle had failed because of lack of visibility when the needle was loaded into the scope.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The 13 patients enrolled had a mean age of 58.15\u2009\u00b1\u200917 years and a male to female ratio of 8:5. Target lesions (mean size 18.6\u2009\u00b1\u20096.4 mm) were lymphadenopathies (9 patients), lung lesions (3 patients) and a pleural nodule (1 patient). Histology core\/s and a definite diagnosis (adenocarcinoma, 4 cases; lymphoma, 2; mesothelioma, 2, metastases from extrathoracic tumors, 2; non\u2010small\u2010cell lung cancer not otherwise specifiable, 1; small cell carcinoma, 1; sarcoidosis, 1) were obtained in 100% of patients. A single case of self\u2010resolving bleeding was the only complication we observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Preliminary results obtained with the dedicated Flex 19G needle are promising, as sample size\/quality is satisfactory and the needle influence on scope flexibility is minimal.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.12736","type":"journal-article","created":{"date-parts":[[2017,11,4]],"date-time":"2017-11-04T05:36:41Z","timestamp":1509773801000},"page":"1725-1731","source":"Crossref","is-referenced-by-count":7,"title":["Endobronchial ultrasound\u2010guided transbronchial needle aspiration with the flexible 19\u2010gauge needle"],"prefix":"10.1111","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1067-4696","authenticated-orcid":false,"given":"Rocco","family":"Trisolini","sequence":"first","affiliation":[{"name":"Interventional Pulmonology Unit, Policlinico S. Orsola\u2010Malpighi and Ospedale Maggiore Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filippo","family":"Natali","sequence":"additional","affiliation":[{"name":"Interventional Pulmonology Unit, Policlinico S. Orsola\u2010Malpighi and Ospedale Maggiore Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Ferrari","sequence":"additional","affiliation":[{"name":"Interventional Pulmonology Unit, Policlinico S. Orsola\u2010Malpighi and Ospedale Maggiore Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanina","family":"Livi","sequence":"additional","affiliation":[{"name":"Interventional Pulmonology Unit, Policlinico S. Orsola\u2010Malpighi and Ospedale Maggiore Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Paioli","sequence":"additional","affiliation":[{"name":"Interventional Pulmonology Unit, Policlinico S. Orsola\u2010Malpighi and Ospedale Maggiore Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Micaela","family":"Romagnoli","sequence":"additional","affiliation":[{"name":"Interventional Pulmonology Unit, Policlinico S. Orsola\u2010Malpighi and Ospedale Maggiore Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Cancellieri","sequence":"additional","affiliation":[{"name":"Pathology Unit, Policlinico S. 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