{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:24:25Z","timestamp":1740147865878,"version":"3.37.3"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,3,24]],"date-time":"2018-03-24T00:00:00Z","timestamp":1521849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001078","name":"Queensland Emergency Medicine Research Foundation","doi-asserted-by":"publisher","award":["EMPJ\u2010108R21\u20102014"],"award-info":[{"award-number":["EMPJ\u2010108R21\u20102014"]}],"id":[{"id":"10.13039\/501100001078","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Shortness of breath is a common presenting symptom to the emergency department (ED) that can arise from a myriad of possible diagnoses. Asthma is one of the major causes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study was to describe the demographic features, clinical characteristics, management and outcomes of adults with an ED diagnosis of asthma who presented to an ED in the Asia Pacific region with a principal symptom of dyspnea.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Planned sub\u2010study of patients with an ED diagnosis of asthma identified in the Asia, Australia and New Zealand Dyspnoea in Emergency Departments (AANZDEM) study. AANZDEM was a prospective cohort study conducted in 46 EDs in Australia, New Zealand, Singapore, Hong Kong and Malaysia over three 72\u00a0hour periods in May, August and October 2014. Primary outcomes were patient epidemiology, clinical features, treatment and outcomes (hospital length of stay (LOS) and mortality).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 3044 patients with dyspnea, 387 (12.7%) patients had an ED diagnosis of asthma. The median age was 45\u00a0years, 60.1% were female, 16.1% were active or recent smokers and 30.4% arrived by ambulance. Inhaled bronchodilator therapy was initiated in 88.1% of patients, and 66.9% received both inhaled bronchodilators and systemic corticosteroids. After treatment in the ED, 65.4% were discharged. No death was reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Asthma is common among patients presenting with a principal symptom of dyspnea in the ED of the Asia Pacific region. There was a suboptimal adherence to international guidelines on investigations and treatments of acute asthma exacerbations presenting an opportunity to improve the efficiency of care.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.12782","type":"journal-article","created":{"date-parts":[[2018,2,23]],"date-time":"2018-02-23T05:59:18Z","timestamp":1519365558000},"page":"2117-2125","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Asthma among adult patients presenting with dyspnea to the emergency department: An observational study"],"prefix":"10.1111","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2134-7842","authenticated-orcid":false,"given":"Win Sen","family":"Kuan","sequence":"first","affiliation":[{"name":"Emergency Medicine Department National University Hospital, National University Health System Singapore, Singapore"},{"name":"Department of Surgery, Yong Loo Lin School of Medicine National University of Singapore Singapore, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Craig","sequence":"additional","affiliation":[{"name":"Emergency Department Monash Medical Centre Clayton Victoria Australia"},{"name":"School of Clinical Sciences Monash University Clayton Victoria Australia"},{"name":"Murdoch Children's Research Institute Parkville Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4655-5023","authenticated-orcid":false,"given":"Anne\u2010Maree","family":"Kelly","sequence":"additional","affiliation":[{"name":"Joseph Epstein Centre for Emergency Medicine Research at Western Health Sunshine Victoria Australia"},{"name":"Faculty of Medicine, Dentistry and Health Sciences The University of Melbourne Parkville Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerben","family":"Keijzers","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Gold Coast University Hospital Gold Coast Queensland Australia"},{"name":"School of Medicine Bond University Gold Coast Queensland Australia"},{"name":"School of Medicine Griffith University Gold Coast Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon","family":"Klim","sequence":"additional","affiliation":[{"name":"Joseph Epstein Centre for Emergency Medicine Research at Western Health Sunshine Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin A","family":"Graham","sequence":"additional","affiliation":[{"name":"Chinese University of Hong Kong, Prince of Wales Hospital Shatin Hong Kong SAR"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Auckland City Hospital Auckland New Zealand"},{"name":"Department of Surgery University of Auckland Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Holdgate","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Liverpool Hospital Sydney New South Wales Australia"},{"name":"University of New South Wales (Southwest Clinical School) Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Lawoko","sequence":"additional","affiliation":[{"name":"Industry Doctoral Training Centre, ATN Universities Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Said","family":"Laribi","sequence":"additional","affiliation":[{"name":"School of Medicine Francois Rabelais University Tours France"},{"name":"Emergency Medicine Department Tours University Hospital Tours France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,24]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_10_2_1","DOI":"10.1164\/rccm.201111-2042ST"},{"unstructured":"World Health Organisation.Fact Sheets Asthma. 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