{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T16:56:27Z","timestamp":1778172987661,"version":"3.51.4"},"reference-count":6,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,1,27]],"date-time":"2019-01-27T00:00:00Z","timestamp":1548547200000},"content-version":"vor","delay-in-days":26,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Risks of endotracheal tube cuff (ETTC) over inflation must be balanced with the need to achieve a minimum pressure of 20\u00a0cm H<jats:sub>2<\/jats:sub>O. Methods have been developed to estimate adequate ETTC pressurization but do not provide accurate endotracheal tube cuff pressure (ETCP) measurements. Hence, different sized syringes may play a role in determining ETCP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Determine optimal syringe size for recommended ETCP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Two hundred patients were randomized to use of either a 10\u2010mL syringe (standard syringe) or a 5\u2010mL syringe (study group) for ETTC inflation. Following the insertion of the endotracheal tube, the ETTC was inflated per the attending anesthesiologist. Within 10 minutes of intubation, ETCP was measured with a hospital\u2010provided manometer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The percentage of in range cuff pressures for the 5\u2010mL group was 10.53% and 6.78% for the 10\u2010mL group. 84.21% (<jats:italic>n<\/jats:italic>\u00a0=\u00a064) of the study group and 91.53% (<jats:italic>n<\/jats:italic>\u00a0=\u00a054) of the control group had cuff pressures exceeding 30 cmH<jats:sub>2<\/jats:sub>O. Although our study did not demonstrate that syringe size was predictive of ideal cuff pressure ranges, the average cuff pressure for the 5\u2010mL group was 55.8\u00a0cm H<jats:sub>2<\/jats:sub>O versus 68.8\u00a0cm H<jats:sub>2<\/jats:sub>O in the 10\u2010mL group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although both 5\u2010 and 10\u2010mL syringes resulted in elevated cuff pressures after intubation, 5\u2010mL syringes resulted in a lower degree of elevation. Use of a 5\u2010mL syringe should be considered when inflating the endotracheal cuff to possibly reduce patient harm secondary to elevated cuff pressures. Further studies assessing smaller syringe sizes to reduce cuff pressures are warranted.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.12984","type":"journal-article","created":{"date-parts":[[2018,12,23]],"date-time":"2018-12-23T10:14:23Z","timestamp":1545560063000},"page":"66-69","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Subglottic perioperative airway\u2014tube inflation via randomized evaluation with variable syringe size (Spair\u2010Tire) study"],"prefix":"10.1111","volume":"13","author":[{"suffix":"II","given":"George W.","family":"Williams","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Neurosurgery, Division of Critical Care Medicine The University of Texas Health Science Center at Houston (UTHealth) McGovern Medical School Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos A.","family":"Artime","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology The University of Texas Health Science Center at Houston (UTHealth) McGovern Medical School Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar L.","family":"Mancillas","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology The University of Texas Health Science Center at Houston (UTHealth) McGovern Medical School Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tariq A.","family":"Syed","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology The University of Texas Health Science Center at Houston (UTHealth) McGovern Medical School Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Tyrone","family":"Burnett","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology The University of Texas Health Science Center at Houston (UTHealth) McGovern Medical School Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Russell","family":"Graham","sequence":"additional","affiliation":[{"name":"Memorial Hermann Hospital\u2010Texas Medical Center Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Tam","sequence":"additional","affiliation":[{"name":"The University of Texas Health Science Center at Houston (UTHealth) McGovern Medical School Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carin A.","family":"Hagberg","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology The University of Texas Health Science Center at Houston (UTHealth) McGovern Medical School Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,1,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2253-4-8"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.288.6422.965"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.4037\/ajcc2011661"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9185.83682"},{"issue":"2","key":"e_1_2_9_6_1","first-page":"166","article-title":"Laboratory evaluation of 4 brands of endotracheal tube cuff inflator","volume":"49","author":"Blanch PB","year":"2004","journal-title":"Respir Care"},{"issue":"6","key":"e_1_2_9_7_1","first-page":"443","article-title":"A comparison of endotracheal tube cuff pressures using estimation techniques and direct intracuff measurement","volume":"71","author":"Stewart SL","year":"2003","journal-title":"AANA J"}],"container-title":["The Clinical Respiratory 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