{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T01:24:19Z","timestamp":1770513859165,"version":"3.49.0"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Sleep\u2010disordered breathing (SDB) and atrial fibrillation (AF) are associated. This study investigated the impact of AF intervention on 6\u2010month home sleep testing data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixty\u2010seven patients (aged 66 to 86, 53% male) with persistent AF were randomized (1:1:1) to direct current cardioversion (DCCV) (22 patients), permanent pacemaker (PPM) + atrioventricular node ablation (AVNA) + DCCV (22 patients) or AF ablation (23 patients). Baseline and 6\u2010month multichannel home sleep tests with the Watch\u2010PAT200 (Itamar Medical Lts., Caesarea, Israel) were recorded. Implantable cardiac monitors (ICMs) (Medtronic Reveal XT, Minneapolis, Minnesota) in the DCCV and AF ablation groups, and PPM Holters in the \u2018pace and ablate\u2019 group were utilized to assess cardiac rhythm beat\u2010to\u2010beat throughout the study period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence of moderate\u2010to\u2010severe SDB [apnoea\u2010hypopnoea index (AHI) \u2265 15\/h] was 60%. At 6\u00a0months there was no change in AHI, Epworth sleepiness scale, sleep time, % REM sleep, respiratory desaturation index or central apnoeic events. Twenty\u2010five patients (15 AF ablation, 9 DCCV and 1 following DCCV post\u2010AVNA) maintained SR at 6\u00a0months confirmed on ICMs in these patients. AHI fell from 29.8\u00a0\u00b1\u00a026.6\/h to 22.2\u00a0\u00b1\u00a020.4\/h; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.049.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>SDB is highly prevalent in patients with persistent AF. Restoration of sinus rhythm, and the associated long\u2010term recovery of haemodynamics, is associated with a significant reduction in AHI. This implicates reversal of fluid shift from the lower limbs to the neck region, a key mechanism in the pathogenesis of SDB.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.13008","type":"journal-article","created":{"date-parts":[[2019,2,22]],"date-time":"2019-02-22T03:49:53Z","timestamp":1550807393000},"page":"280-288","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The effect of atrial fibrillation intervention on nocturnal respiratory events in elderly patients with persistent AF"],"prefix":"10.1111","volume":"13","author":[{"given":"William","family":"Eysenck","sequence":"first","affiliation":[{"name":"Cardiology Research Department Eastbourne General Hospital Eastbourne United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil","family":"Sulke","sequence":"additional","affiliation":[{"name":"Cardiology Research Department Eastbourne General Hospital Eastbourne United 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