{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T16:14:16Z","timestamp":1782231256310,"version":"3.54.5"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,11,14]],"date-time":"2019-11-14T00:00:00Z","timestamp":1573689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Respiratory J"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Idiopathic pulmonary fibrosis (IPF) is the most common and severe form of idiopathic interstitial pneumonia, accounted for 20% of cases of interstitial lung disease (ILD). In this study, we sought to compare the lung changes of IPF using a lung ultrasound (LUS) protocol of 12 zones with \u201ccurrent standard\u201d high resolution computed tomography (HRCT) diagnostic method and overlap it with the functional pulmonary test as a complete clinical and imaging evaluation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty\u2010one patients were included in the study and performed HRCT and pulmonary functional tests (PFT). A 12\u2010lung zones' LUS protocol was used and compared with HRCT and PFT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The HRCT total fibrotic score had a correlation coefficient of 0.454 (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.005) with predicted FVC and 0.713 with predicted DLCO (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). Both the median of the number of B\u2010lines and the average of the thickness of the pleural line obtained in the LUS assessment had a positively and statistically significant correlation with the HRCT fibrotic score <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001. The pleural thickness of 2.4\u00a0mm is the cut\u2010off value of the mild form of fibrosis with a sensitivity of 0.958 and a specificity of 0.994.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>B\u2010lines and the average thickness of the pleural line as LUS markers of the fibrotic interstitial syndrome are highly and positively correlated with HRCT score, FVC and DLCO. LUS as a complementary method in the clinical management of IPF could be used more often by skilled clinicians to assess patients in terms of possible diagnosis and monitoring of IPF.<\/jats:p><\/jats:sec>","DOI":"10.1111\/crj.13101","type":"journal-article","created":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T20:43:54Z","timestamp":1572641034000},"page":"54-63","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Ultrasound mapping of lung changes in idiopathic pulmonary fibrosis"],"prefix":"10.1111","volume":"14","author":[{"given":"Diana","family":"Manolescu","sequence":"first","affiliation":[{"name":"Department of Radiology University of Medicine and Pharmacy \u201cVictor Babes\u201d Timisoara Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2083-0581","authenticated-orcid":false,"given":"Cristian","family":"Oancea","sequence":"additional","affiliation":[{"name":"Department of Pulmonology University of Medicine and Pharmacy \u201cVictor Babes\u201d Timisoara Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bogdan","family":"Timar","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Medical Informatics University of Medicine and Pharmacy \u201cVictor Babes\u201d Timisoara Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Traila","sequence":"additional","affiliation":[{"name":"Department of Pulmonology University of Medicine and Pharmacy \u201cVictor Babes\u201d Timisoara Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Malita","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Medicine and Pharmacy \u201cVictor Babes\u201d Timisoara Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florica","family":"Birsasteanu","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Medicine and Pharmacy \u201cVictor Babes\u201d Timisoara Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Voicu","family":"Tudorache","sequence":"additional","affiliation":[{"name":"Department of Pulmonology University of Medicine and Pharmacy \u201cVictor Babes\u201d Timisoara Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,11,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60052-4"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmr.2017.07.017"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2009-040GL"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201807-1255ST"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-012-2513-4"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2006.02.013"},{"issue":"2","key":"e_1_2_9_8_1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.15403\/jgld.2014.1121.252.lsf","article-title":"Liver stiffness evaluation by transient elastography in type 2 diabetes mellitus patients with ultrasound\u2010proven steatosis","volume":"25","author":"Sporea I","year":"2016","journal-title":"J Gastroin Liver Dis"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.156.5.96-07096"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2004.02.012"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kep263"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2011-201072"},{"key":"e_1_2_9_13_1","first-page":"S87","article-title":",Brickmann K et al. 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